Search Results - "Zakaroff, Alexia"

Cytokine storm induced by a PD1 inhibitor in a renal transplant patient by Del Bello, Arnaud, Zakaroff, Alexia G., Meyer, Nicolas, Delas, Audrey, Faguer, Stanislas, Kamar, Nassim, Belliere, Julie

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Body fat reduction without cardiovascular changes in mice after oral treatment with the MAO inhibitor phenelzine by Carpéné, Christian, Mercader, Josep, Le Gonidec, Sophie, Schaak, Stéphane, Mialet‐Perez, Jeanne, Zakaroff‐Girard, Alexia, Galitzky, Jean

“…Background and Purpose Phenelzine is an antidepressant drug known to increase the risk of hypertensive crisis when dietary tyramine is not restricted. However,…”
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Notch activation shifts the fate decision of senescent progenitors toward myofibrogenesis in human adipose tissue by Boulet, Nathalie, Briot, Anaïs, Jargaud, Valentin, Estève, David, Rémaury, Anne, Belles, Chloé, Viana, Pénélope, Fontaine, Jessica, Murphy, Lucie, Déon, Catherine, Guillemot, Marie, Pech, Catherine, Veeranagouda, Yaligara, Didier, Michel, Decaunes, Pauline, Mouisel, Etienne, Carpéné, Christian, Iacovoni, Jason S., Zakaroff‐Girard, Alexia, Grolleau, Jean‐Louis, Galitzky, Jean, Ledoux, Séverine, Guillemot, Jean‐Claude, Bouloumié, Anne

“…Senescence is a key event in the impairment of adipose tissue (AT) function with obesity and aging but the underlying molecular and cellular players remain to…”
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Preadipocytes in the human subcutaneous adipose tissue display distinct features from the adult mesenchymal and hematopoietic stem cells by Sengenès, Coralie, Lolmède, Karine, Zakaroff-Girard, Alexia, Busse, Rudi, Bouloumié, Anne

“…The stroma‐vascular fraction (SVF) of human adipose tissue has recently been described to be composed of endothelial cells identified as CD34+/CD31+ cells,…”
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Randomized Clinical Trial: Effects of β-Hydroxy-β-Methylbutyrate (HMB)-Enriched vs. HMB-Free Oral Nutritional Supplementation in Malnourished Cirrhotic Patients by Espina, Silvia, Sanz-Paris, Alejandro, Gonzalez-Irazabal, Yolanda, Pérez-Matute, Patricia, Andrade, Fernando, Garcia-Rodriguez, Beatriz, Carpéné, Christian, Zakaroff, Alexia, Bernal-Monterde, Vanesa, Fuentes-Olmo, Javier, Arbones-Mainar, Jose M

“…β-Hydroxy-β-methylbutyrate (HMB) supplementation increases muscle and strength mass in some muscle-wasting disorders. Malnutrition and sarcopenia are often…”
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Human White and Brite Adipogenesis is Supported by MSCA1 and is Impaired by Immune Cells by Estève, David, Boulet, Nathalie, Volat, Fanny, Zakaroff‐Girard, Alexia, Ledoux, Séverine, Coupaye, Muriel, Decaunes, Pauline, Belles, Chloé, Gaits‐Iacovoni, Frederique, Iacovoni, Jason S., Rémaury, Anne, Castel, Benjamin, Ferrara, Pascual, Heymes, Christophe, Lafontan, Max, Bouloumié, Anne, Galitzky, Jean

“…Obesity‐associated inflammation contributes to the development of metabolic diseases. Although brite adipocytes have been shown to ameliorate metabolic…”
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Immune Cell Toll-like Receptor 4 Mediates the Development of Obesity- and Endotoxemia-Associated Adipose Tissue Fibrosis by Vila, Isabelle K., Badin, Pierre-Marie, Marques, Marie-Adeline, Monbrun, Laurent, Lefort, Corinne, Mir, Lucile, Louche, Katie, Bourlier, Virginie, Roussel, Balbine, Gui, Philippe, Grober, Jacques, Štich, Vladimír, Rossmeislová, Lenka, Zakaroff-Girard, Alexia, Bouloumié, Anne, Viguerie, Nathalie, Moro, Cedric, Tavernier, Geneviève, Langin, Dominique

“…Adipose tissue fibrosis development blocks adipocyte hypertrophy and favors ectopic lipid accumulation. Here, we show that adipose tissue fibrosis is…”
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TGFbeta family members are key mediators in the induction of myofibroblast phenotype of human adipose tissue progenitor cells by macrophages by Bourlier, Virginie, Sengenès, Coralie, Zakaroff-Girard, Alexia, Decaunes, Pauline, Wdziekonski, Brigitte, Galitzky, Jean, Villageois, Phi, Esteve, David, Chiotasso, Patrick, Dani, Christian, Bouloumié, Anne

“…The present study was undertaken to characterize the remodeling phenotype of human adipose tissue (AT) macrophages (ATM) and to analyze their paracrine effects…”
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Subcutaneous Stromal Cells and Visceral Adipocyte Size Are Determinants of Metabolic Flexibility in Obesity and in Response to Weight Loss Surgery by Ledoux, Séverine, Boulet, Nathalie, Belles, Chloé, Zakaroff-Girard, Alexia, Bernard, Arnaud, Germain, Albéric, Decaunes, Pauline, Briot, Anaïs, Galitzky, Jean, Bouloumié, Anne

“…Adipose tissue (AT) expansion either through hypertrophy or hyperplasia is determinant in the link between obesity and metabolic alteration. The present study…”
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Inhibition of human preadipocyte proteasomal activity by HIV protease inhibitors or specific inhibitor lactacystin leads to a defect in adipogenesis, which involves matrix metalloproteinase-9 by De Barros, Sandra, Zakaroff-Girard, Alexia, Lafontan, Max, Galitzky, Jean, Bourlier, Virginie

“…In a previous publication, we reported that human immunodeficiency virus (HIV) protease inhibitors (PIs) inhibited the differentiation of human preadipocytes…”
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Natriuretic peptide-dependent lipolysis in fat cells is a primate specificity by Sengenès, Coralie, Zakaroff-Girard, Alexia, Moulin, Agnès, Berlan, Michel, Bouloumié, Anne, Lafontan, Max, Galitzky, Jean

“…We have recently demonstrated that natriuretic peptides (NPs), which are known for regulation of blood pressure via membrane guanylyl cyclase (GC) receptors,…”
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Protease inhibitor treatments reveal specific involvement of matrix metalloproteinase-9 in human adipocyte differentiation by Bourlier, Virginie, Zakaroff-Girard, Alexia, De Barros, Sandra, Pizzacalla, Christophe, de Saint Front, Véronique Durand, Lafontan, Max, Bouloumié, Anne, Galitzky, Jean

“…We previously showed that human and murine 3T3-F442A preadipocytes produced and released matrix metalloproteinases (MMPs) 2 and 9 and that a treatment by MMP…”
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Effects of the amino acid derivatives, β-hydroxy-β-methylbutyrate, taurine, and N-methyltyramine, on triacylglycerol breakdown in fat cells by Leroux, Mélanie, Lemery, Tristan, Boulet, Nathalie, Briot, Anaïs, Zakaroff, Alexia, Bouloumié, Anne, Andrade, Fernando, Pérez-Matute, Patricia, Arbones-Mainar, Jose M., Carpéné, Christian

“…Various amino acid (AA) metabolites are used as supplements to facilitate metabolic control and enhance responsiveness of insulin-sensitive tissues…”
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Effects of a longitudinal training program on responses to exercise in overweight men by Crampes, F, Marion-Latard, F, Zakaroff-Girard, A, Glisezinski, I. de, Harant, I, Thalamas, C, Stich, V, Riviere, D, Lafontan, M, Berlan, M

“…Objective: The aim of this study was to determine how training modifies metabolic responses and lipid oxidation in overweight young male subjects. Research…”
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α2‐adrenergic receptor‐mediated release of lysophosphatidic acid by adipocytes: A paracrine signal for preadipocyte growth by Pagès, Céline, Valet, Philippe, Jeanneton, Olivier, Zakaroff‐Girard, Alexia, Barbe, Pierre, Record, Michel, Wolf, Claude, Chevy, Françoise, Lafontan, Max, Saulnier‐Blache, Jean Sébastien

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Specific macrophage subtypes influence the progression of rhabdomyolysis-induced kidney injury by Belliere, Julie, Casemayou, Audrey, Ducasse, Laure, Zakaroff-Girard, Alexia, Martins, Frédéric, Iacovoni, Jason S, Guilbeau-Frugier, Céline, Buffin-Meyer, Bénédicte, Pipy, Bernard, Chauveau, Dominique, Schanstra, Joost P, Bascands, Jean-Loup

“…Rhabdomyolysis can be life threatening if complicated by AKI. Macrophage infiltration has been observed in rat kidneys after glycerol-induced rhabdomyolysis,…”
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MO278: Immunolandscaping of Rhabdomyolysis-Induced Acute Kidney Injury by Rao, Snigdha, Casemayou, Audrey, Buleon, Marie, Feuillet, Guylene, Riant, Elodie, Zakaroff-Girard, Alexia, Martins, Frédéric, Gonzalez-Fuentes, Ignacio, Sébastien Saulnier Blache, Jean, Schanstra, Joost, Belliere, Julie

“…Abstract BACKGROUND AND AIMS Acute kidney injury (AKI) accounts for 13.3 million cases per year worldwide and further responsible for 1.7 million deaths per…”
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Interplay Between Human Adipocytes and T Lymphocytes in Obesity: CCL20 as an Adipochemokine and T Lymphocytes as Lipogenic Modulators by Duffaut, Carine, Zakaroff-Girard, Alexia, Bourlier, Virginie, Decaunes, Pauline, Maumus, Marie, Chiotasso, Patrick, Sengenès, Coralie, Lafontan, Max, Galitzky, Jean, Bouloumié, Anne

“…OBJECTIVE—Adipose tissue (AT) plays a major role in the low-grade inflammatory state associated with obesity. The aim of the present study was to characterize…”
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5715 IMMUNE LANDSCAPING IN RHABDOMYOLYSIS INDUCED ACUTE KIDNEY INJURY IDENTIFIES SENESCENCE AS A POTENTIAL TARGET by Rao, Snigdha N, Zahm, Margot, Buleon, Marie, Casemayou, Audrey, Faguer, Stanislas, Feuillet, Guylene, Iacovoni, Jason, Joffre, Olivier, Gonzalez-Fuentes, Ignacio, Martins, Frédéric, Riant, Elodie, Zakaroff-Girard, Alexia, Schanstra, Joost, Blache, Jean Sébastien Saulnier, Belliere, Julie

“…Abstract Background and Aims Worldwide, acute kidney injury (AKI) has an incidence of 13.3 million cases per year leading to 1.7 million deaths. Rhabdomyolysis…”
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Single-cell RNA sequencing identifies senescence as therapeutic target in rhabdomyolysis-induced acute kidney injury by Rao, Snigdha N, Zahm, Margot, Casemayou, Audrey, Buleon, Marie, Faguer, Stanislas, Feuillet, Guylène, Iacovoni, Jason S, Joffre, Olivier P, Gonzalez-Fuentes, Ignacio, Lhuillier, Emeline, Martins, Frédéric, Riant, Elodie, Zakaroff-Girard, Alexia, Schanstra, Joost P, Saulnier-Blache, Jean Sébastien, Belliere, Julie

“…ABSTRACT Background The role of macrophages in the development of rhabdomyolysis-induced acute kidney injury (RM-AKI) has been established, but an in-depth…”
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