Search Results - "Zajic, S."

Rifampin's Acute Inhibitory and Chronic Inductive Drug Interactions: Experimental and Model-Based Approaches to Drug-Drug Interaction Trial Design by Reitman, ML, Chu, X, Cai, X, Yabut, J, Venkatasubramanian, R, Zajic, S, Stone, JA, Ding, Y, Witter, R, Gibson, C, Roupe, K, Evers, R, Wagner, JA, Stoch, A

“…We studied the time course for the reversal of rifampin's effect on the pharmacokinetics of oral midazolam (a cytochrome P450 (CYP) 3A4 substrate) and digoxin…”
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Effect of the Cathepsin K Inhibitor Odanacatib on Bone Resorption Biomarkers in Healthy Postmenopausal Women: Two Double-Blind, Randomized, Placebo-Controlled Phase I Studies by Stoch, SA, Zajic, S, Stone, J, Miller, DL, Van Dyck, K, Gutierrez, MJ, De Decker, M, Liu, L, Liu, Q, Scott, BB, Panebianco, D, Jin, B, Duong, LT, Gottesdiener, K, Wagner, JA

“…Inhibition of cathepsin K (CatK) is a potential new treatment for osteoporosis. In two double‐blind, randomized, placebo‐controlled phase I studies,…”
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Model based meta analysis to characterize the dose-efficacy profile of recombinant FSH for controlled ovarian stimulation by Zhang, D, Stegmann, B.J, Zajic, S, Gheyas, F, Guan, Y, Jadhav, P

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Surgical Treatment of Choledocholythiasis – Five Years’ Experience 2017-2021 by Isailovic, N., Jovanovic, M., Zajic, S., Milosavljevic, I.

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Theoretic Criteria for Antibody Penetration into Solid Tumors and Micrometastases by Thurber, Greg M, Zajic, Stefan C, Wittrup, K. Dane

“…Targeting tumors with antibody-based therapeutics is a complex task presenting multiple kinetic barriers. Antibody internalization and clearance inhibit uptake…”
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The Absolute Bioavailability and Effect of Food on the Pharmacokinetics of Odanacatib: A Stable-Label i.v./Oral Study in Healthy Postmenopausal Women by Zajic, Stefan, Rossenu, Stefaan, Hreniuk, David, Kesisoglou, Filippos, McCrea, Jacqueline, Liu, Fang, Sun, Li, Witter, Rose, Gauthier, Don, Helmy, Roy, Joss, Darrick, Ni, Tong, Stoltz, Randall, Stone, Julie, Stoch, S Aubrey

“…A stable-label i.v./oral study design was conducted to investigate the pharmacokinetics (PK) of odanacatib. Healthy, postmenopausal women received oral doses…”
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Coadministration of Rifampin Significantly Reduces Odanacatib Concentrations in Healthy Subjects by Stoch, S. Aubrey, Ballard, Jeanine, Gibson, Christopher, Kesisoglou, Filippos, Witter, Rose, Kassahun, Kelem, Zajic, Stefan, Mehta, Anish, Brandquist, Christine, Dempsey, Cynthia, Stypinski, Daria, Reitman, Marc L.

“…This open‐label 2‐period study assessed the effect of multiple‐dose administration of rifampin, a strong cytochrome P450 3A (CYP3A) and P‐glycoprotein inducer,…”
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Odanacatib Pharmacokinetics Comparison Between Chinese and Non‐Chinese Postmenopausal Women by Chen, Xia, Jiang, Ji, Hu, Pei, Zajic, Stefan, Liu, Wen, McCrea, Jacqueline, Liu, Fang, Witter, Rose, Mangin, Eric, Stoch, S. Aubrey

“…Odanacatib (ODN), an oral selective inhibitor of cathepsin K, was an investigational agent previously in development for the treatment of osteoporosis. In this…”
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Quasi-Experimental Research as An Epistemological-Methodological Approach in Education Research by Osmanović Zajić, Jelena, Maksimović, Jelena

“…Pedagogy as a social-humanistic science that deals with upbringing and education expresses its complexity through a plurality of ideas, understandings and…”
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Influence of Residual Water on the Adsorption of Atmospheric Gases in Li−X Zeolite:  Experiment and Simulation by Hutson, Nick D, Zajic, Stefan C, Yang, Ralph T

“…Li−LSX zeolite (Si/Al = 1.0) is currently the best sorbent in use in the separation of air by adsorption processes. In this present work we have synthesized…”
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Prediction of fully developed turbulent convection with minimal explicit empiricism by Churchill, Stuart W., Zajic, Stefan C.

“…From a purely theoretical analogy between energy and momentum transfer in fully developed turbulent Convection, an expression without explicit empiricism, and…”
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