Search Results - "Zajac, D J"

Increase in visceral and subcutaneous abdominal fat in men with prostate cancer treated with androgen deprivation therapy by Hamilton, E. J., Gianatti, E., Strauss, B. J., Wentworth, J., Lim-Joon, D., Bolton, D., Zajac, J. D., Grossmann, M.

“…Summary Objective  Androgen deprivation therapy (ADT) for prostate cancer is associated with increases in fat mass and risk of type 2 diabetes; however, the…”
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Structural Decay of Bone Microarchitecture in Men with Prostate Cancer Treated with Androgen Deprivation Therapy by Hamilton, E. J, Ghasem-Zadeh, A, Gianatti, E, Lim-Joon, D, Bolton, D, Zebaze, R, Seeman, E, Zajac, J. D, Grossmann, M

“…Context: Androgen deprivation therapy (ADT) used in the treatment of prostate cancer reduces bone mineral density (BMD) and predisposes to fractures. The…”
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Female Mice Haploinsufficient for an Inactivated Androgen Receptor (AR) Exhibit Age-Dependent Defects That Resemble the AR Null Phenotype of Dysfunctional Late Follicle Development, Ovulation, and Fertility by Walters, K. A, Allan, C. M, Jimenez, M, Lim, P. R, Davey, R. A, Zajac, J. D, Illingworth, P, Handelsman, D. J

“…The role of classical genomic androgen receptor (AR) mediated actions in female reproductive physiology remains unclear. Female mice homozygous for an in-frame…”
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Genomic actions of the androgen receptor are required for normal male sexual differentiation in a mouse model by Notini, A J, Davey, R A, McManus, J F, Bate, K L, Zajac, J D

“…Androgens mediate their effects in target cells via the androgen receptor (AR), which acts predominantly as a ligand-dependent transcription factor. In…”
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Cardiovascular risk and bone loss in men undergoing androgen deprivation therapy for non‐metastatic prostate cancer: implementation of standardized management guidelines by Cheung, A. S., Pattison, D., Bretherton, I., Hoermann, R., Lim Joon, D., Ho, E., Jenkins, T., Hamilton, E. J., Bate, K., Chan, I., Zajac, J. D., Grossmann, M.

“…Summary Our objective was to evaluate the effectiveness of implementing standardized guidelines to mitigate metabolic and bone side effects of androgen…”
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Effect of the androgen receptor CAG repeat polymorphism on transcriptional activity: specificity in prostate and non-prostate cell lines by Beilin, J, Ball, EM, Favaloro, JM, Zajac, JD

“…The action of androgens is essential for the development of benign prostatic hyperplasia and carcinoma of the prostate. The androgen receptor is a…”
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Obesity and age as dominant correlates of low testosterone in men irrespective of diabetes status by Ng Tang Fui, M., Hoermann, R., Cheung, A. S., Gianatti, E. J., Zajac, J. D., Grossmann, M.

“…Summary Although men with type 2 diabetes (T2D) frequently have lowered testosterone levels, it is not well established whether this is ascribable to the…”
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Assessment of aspiration risk in stroke patients with quantification of voluntary cough by HAMMOND, C. A, GOLDSTEIN, L. B, ZAJAC, D. J, GRAY, L, DAVENPORT, P. W, BOLSER, D. C

“…Dysphagia and subsequent aspiration are serious complications of acute stroke that may be related to an impaired cough reflex. It was hypothesized that…”
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Men with Kennedy disease have a reduced risk of androgenetic alopecia by Sinclair, R., Greenland, K.J., Egmond, S. van, Hoedemaker, C., Chapman, A., Zajac, J.D.

“…Summary Background  Spinal and bulbar muscular atrophy or Kennedy disease (KD) is an X‐linked neurodegenerative disease caused by an expansion of a polymorphic…”
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Structural Decay of Bone Microarchitecture in Men with Prostate Cancer Treated with Androgen Deprivation Therapy by Hamilton, E. J, Ghasem-Zadeh, A, Gianatti, E, Lim-Joon, D, Bolton, D, Zebaze, R, Seeman, E, Zajac, J. D, Grossmann, M

“…J Clin Endocrinol Metab, 10.1210/jc.2010-0902…”
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Structural Decay of Bone Microarchitecture in Men with Prostate Cancer Treated with Androgen Deprivation Therapy by Hamilton, E. J, Ghasem-Zadeh, A, Gianatti, E, Lim-Joon, D, Bolton, D, Zebaze, R, Seeman, E, Zajac, J. D, Grossmann, M

“…J Clin Endocrinol Metab, 10.1210/jc.2010-0902…”
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Kennedy's disease: pathogenesis and clinical approaches by Greenland, K. J., Zajac, J. D.

“…Kennedy's disease, also known as spinal and bulbar muscular atrophy, is a progressive degenerative con­dition affecting lower motor neurons. It is one of nine…”
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Correlation of visceral adipose tissue measured by Lunar Prodigy dual X-ray absorptiometry with MRI and CT in older men by Cheung, A S, de Rooy, C, Hoermann, R, Gianatti, E J, Hamilton, E J, Roff, G, Zajac, J D, Grossmann, M

“…Quantification of abdominal visceral adipose tissue (VAT) is important to understand obesity-related comorbidities. We hypothesized that dual X-ray…”
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Symptomatic response to testosterone treatment in dieting obese men with low testosterone levels in a randomized, placebo-controlled clinical trial by Ng Tang Fui, M, Hoermann, R, Prendergast, L A, Zajac, J D, Grossmann, M

“…Background: Obese men commonly have reductions in circulating testosterone and report symptoms consistent with androgen deficiency. We hypothesized that…”
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Falls Relate to Vitamin D and Parathyroid Hormone in an Australian Nursing Home and Hostel by Stein, Mark S., Wark, John D., Scherer, Samuel C., Walton, S. Lynette, Chick, Patricia, Di Carlantonio, Margaret, Zajac, Jeffrey D., Flicker, Leon

“…OBJECTIVES: To determine whether falling relates to serum levels of vitamin D and parathyroid hormone. DESIGN: A cross‐sectional study with retrospective…”
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Transgenic mice that express Cre recombinase in osteoclasts by Chiu, W.S.M., McManus, J.F., Notini, A.J., Cassady, A.I., Zajac, J.D., Davey, R.A.

“…To study the physiological control of osteoclasts, the bone resorbing cells, we generated transgenic mice carrying the Cre recombinase gene driven by either…”
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Threshold effects of glucose transporter-4 (GLUT4) deficiency on cardiac glucose uptake and development of hypertrophy by Kaczmarczyk, SJ, Andrikopoulos, S, Favaloro, J, Domenighetti, AA, Dunn, A, Ernst, M, Grail, D, Fodero-Tavoletti, M, Huggins, CE, Delbridge, LM, Zajac, JD, Proietto, J

“…The aim of this study was to investigate the metabolic and structural consequences of a decrease in glucose transporter-4 (GLUT4) levels on the heart. The…”
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Germline dinucleotide mutation in codon 883 of the RET proto-oncogene in multiple endocrine neoplasia type 2B without codon 918 mutation by GIMM, O, MARSH, D. J, ANDREW, S. D, FRILLING, A, DAHIA, P. L. M, MULLIGAN, L. M, ZAJAC, J. D, ROBINSON, B. G, ENG, C

“…The autosomal dominant multiple endocrine neoplasia type 2 syndromes (MEN 2) comprise three clinically distinct entities, MEN 2A, familial medullary thyroid…”
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Parathyroid Hormone-Related Protein Purified from a Human Lung Cancer Cell Line by Moseley, J. M., Kubota, M., Diefenbach-Jagger, H., Wettenhall, R. E. H., Kemp, B. E., Suva, L. J., Rodda, C. P., Ebeling, P. R., Hudson, P. J., Zajac, J. D., Martin, T. J.

“…A protein with biological activities similar to parathyroid hormone (PTH) has been purified from serum-free culture medium obtained from a human lung cancer…”
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Peripheral insulin resistance develops in transgenic rats overexpressing phosphoenolpyruvate carboxykinase in the kidney by LAMONT, B. J, ANDRIKOPOULOS, S, FUNKAT, A, FAVALORO, J, YE, J. M, KRAEGEN, E. W, HOWLETT, K. F, ZAJAC, J. D, PROIETTO, J

“…To study the secondary consequences of impaired suppression of endogenous glucose production (EGP) we have created a transgenic rat overexpressing the…”
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