Search Results - "Zaitsu, Masaaki"
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The Efficacy of the Hepatocyte Spheroids for Hepatocyte Transplantation
Published in Cell transplantation (2021)“…The safety and short-term efficacy of hepatocyte transplantation (HCTx) have been widely proven. However, issues such as reduced viability and/or function of…”
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Occupational disparities in tumor grade and cytosolic HMGB1 expression in renal cell cancer
Published in Journal of occupational health (01-01-2022)“…Objectives We sought to examine occupational disparities in tumor grade and cytosolic expression of high‐mobility group box‐1 (HMGB1) among renal cell cancer…”
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Functional roles of graft-infiltrating lymphocytes during early-phase post-transplantation in mouse cardiac transplantation models
Published in Transplant international (01-12-2021)“…Immunological behavior of graft-infiltrating lymphocytes (GILs) determines the graft fate (i.e., rejection or acceptance). Nevertheless, the functional…”
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Outcome of Living-Donor Liver Transplantation Using Grafts from Donors Treated for Fatty Liver
Published in Annals of transplantation (10-01-2020)Get full text
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Immunosuppressive effects of DTCM-G, a novel inhibitor of the mTOR downstream signaling pathway
Published in Transplantation (27-02-2013)“…A newly developed compound, 3-[(dodecylthiocarbonyl)methyl]-glutarimide (DTCM-G), has been shown to inhibit nuclear translocation of c-Fos/c-Jun in a murine…”
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Novel anti-inflammatory agent 3-[(dodecylthiocarbonyl)-methyl]-glutarimide ameliorates murine models of inflammatory bowel disease
Published in Inflammation research (01-03-2016)“…Objective and design To examine the effect of 3-[(dodecylthiocarbonyl)-methyl]-glutarimide (DTCM-G), a novel anti-inflammatory agent that inhibits…”
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Antagonist Anti-CD28 Therapeutics for the Treatment of Autoimmune Disorders
Published in Antibodies (Basel) (01-12-2017)“…The effector functions of T lymphocytes are responsible for most autoimmune disorders and act by directly damaging tissues or by indirectly promoting…”
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A pilot study of operational tolerance with a regulatory T‐cell‐based cell therapy in living donor liver transplantation
Published in Hepatology (Baltimore, Md.) (01-08-2016)“…Potent immunosuppressive drugs have significantly improved early patient survival after liver transplantation (LT). However, long‐term results remain…”
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Early graft‐infiltrating lymphocytes are not associated with graft rejection in a mouse model of skin transplantation
Published in Scandinavian journal of immunology (01-10-2024)“…Graft‐infiltrating lymphocytes (GILs) play an important role in promoting rejection after organ transplantation. We recently reported that GILs that…”
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Novel immunological approach to asses donor reactivity of transplant recipients using a humanized mouse model
Published in Human immunology (01-07-2020)“…In organ transplantation, a reproducible and robust immune-monitoring assay has not been established to determine individually tailored immunosuppressants…”
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The Immune Monitoring for Operationally Tolerant Recipients Following a Regulatory T cell-based Cell Therapy
Published in Transplantation (01-07-2018)“…BACKGROUND AND AIMWe have firstly demonstrated that regulatory T cell (Treg)-enriched cell therapy efficiently promotes an operational tolerance in 7 of 10…”
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Selective blockade of CD28 on human T cells facilitates regulation of alloimmune responses
Published in JCI insight (05-10-2017)“…T cells are central to the detrimental alloresponses that develop in autoimmunity and transplantation, with CD28 costimulatory signals being key to T cell…”
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3-[(Dodecylthiocarbonyl)Methyl]-Glutarimide Attenuates Graft Arterial Disease by Suppressing Alloimmune Responses and Vascular Smooth Muscle Cell Proliferation
Published in Transplantation (01-05-2015)“…BACKGROUNDGraft arterial disease (GAD) is a major cause of late graft loss after organ transplantation. Alloimmune responses and vascular remodeling eventually…”
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Cell mediated rejection
Published in Methods in molecular biology (Clifton, N.J.) (2013)“…Rejection is the major barrier to successful transplantation and usually results from the integration of multiple mechanisms. Activation of elements of the…”
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Dendritic Cells Conditioned With NK026680 Prolong Cardiac Allograft Survival in Mice
Published in Transplantation (27-06-2012)“…Pharmacologically modulated dendritic cells (DCs) can potentially regulate alloimmune responses. We examined the characteristics of immunoregulatory DCs…”
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Immunomodulatory Effect of Nuclear Factor-κB Inhibition by Dehydroxymethylepoxyquinomicin in Combination With Donor-Specific Blood Transfusion
Published in Transplantation (27-04-2012)“…Nuclear factor-κB (NF-κB) is a key molecule in alloimmune responses, however, its role in tolerance induction is not clear. We have previously reported that…”
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Small intestinal intussusceptions due to the placement of a percutaneous endoscopic jejunostomy tube
Published in BMJ case reports (2011)“…Percutaneous endoscopic jejunostomy (PEJ) has been developed and is considered to be a better method than percutaneous endoscopic gastrostomy for preventing…”
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Small intestinal intussusceptions due to the placement of a percutaneous endoscopic jejunostomy tube
Published in BMJ Case Reports (2011)“…Percutaneous endoscopic jejunostomy (PEJ) has been developed and is considered to be a better method than percutaneous endoscopic gastrostomy for preventing…”
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