Risk Factors Associated With the Development of Acute Peripancreatic Fluid Collections on Follow-Up Imaging After Acute Pancreatitis: What Physicians Need to Know

Risk Factors Associated With the Development of Acute Peripancreatic Fluid Collections on Follow-Up Imaging After Acute Pancreatitis: What Physicians Need to Know

This study aims to identify various risk factors for acute peripancreatic fluid collections (APFCs) in patients presenting with acute pancreatitis (AP). A blinded retrospective case-control study was conducted at a tertiary care hospital in Riyadh. Data from 327 patients who presented with AP betwee...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) Vol. 15; no. 12; p. e50471
Main Authors: Molla, Nouran W, Zaini, Renad H, Alfaiz, Fahad A, Alkhayatt, Ahmad M, AlJohani, Majed A, Alomar, Mohammed O, Aljohani, Abdulaziz A, BinMayouf, Mohammed S, Alyamani, Abduljabbar A, Alsergani, Abdullah H
Format: Journal Article
Language:English
Published: United States Cureus Inc 13-12-2023
Cureus
Subjects:
Age
Comorbidity
Cysts
Data collection
Diabetes
Endoscopy
Etiology
Gastroenterology
Gender
General Surgery
Hospitals
Hypertension
Liver cirrhosis
Medical records
Metabolic disorders
Pancreatitis
Patients
Radiology
Regression analysis
Risk factors
predictors
apfc
acute peripancreatic fluid collections
risk factors
radiology
acute pancreatitis
retrospective
pancreatitis
follow-up imaging
incidence
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Summary:This study aims to identify various risk factors for acute peripancreatic fluid collections (APFCs) in patients presenting with acute pancreatitis (AP). A blinded retrospective case-control study was conducted at a tertiary care hospital in Riyadh. Data from 327 patients who presented with AP between January 2008 and 2021 were analyzed. Following the application of inclusion/exclusion criteria, the final sample size consisted of 82 patients. Patients were divided into cases and controls based on the presence or absence of APFCs, respectively. APFCs were defined as fluid collections in the peripancreatic region that develop within four weeks of presentation without well-defined walls or solid internal components. Demographic, clinical, and laboratory variables were collected and subjected to multivariate binary regression analysis to assess the odds of developing APFCs. A total of 34 patients were categorized as cases, while 48 patients were controls. A significant association was found between age (P=0.022), total bilirubin (P=0.012), lipase level (P<0.001), albumin level (P=0.038), and lactate dehydrogenase (LDH) (P=0.037) on admission and the odds of developing APFCs. Older age, higher levels of bilirubin and lipase, and low levels of albumin and LDH were found to be risk factors for developing APFCs. No other variables were found to be significant. The findings of this study may provide insight into how often clinicians can expect APFCs in patients presenting with AP.
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ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.50471