Search Results - "Zahraoui, Ahmed"
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Secretion of VGF relies on the interplay between LRRK2 and post-Golgi v-SNAREs
Published in Cell reports (Cambridge) (28-03-2023)“…The neuropeptide VGF was recently proposed as a neurodegeneration biomarker. The Parkinson’s disease-related protein leucine-rich repeat kinase 2 (LRRK2)…”
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2
Tight Junction, a Platform for Trafficking and Signaling Protein Complexes
Published in The Journal of cell biology (27-11-2000)“…Epithelial cells are associated laterally in a sheet, with the apical surface facing the lumina, often covered by microvilli, and the basolateral side…”
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3
Rab13 Regulates PKA Signaling during Tight Junction Assembly
Published in The Journal of cell biology (26-04-2004)“…The GTPase Rab13 regulates the assembly of functional epithelial tight junctions (TJs) through a yet unknown mechanism. Here, we show that expression of the…”
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4
MICAL-like1 mediates epidermal growth factor receptor endocytosis
Published in Molecular biology of the cell (15-09-2011)“…Small GTPase Rabs are required for membrane protein sorting/delivery to precise membrane domains. Rab13 regulates epithelial tight junction assembly and…”
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5
Role of Tetanus Neurotoxin Insensitive Vesicle-Associated Membrane Protein (TI-VAMP) in Vesicular Transport Mediating Neurite Outgrowth
Published in The Journal of cell biology (15-05-2000)“…How vesicular transport participates in neurite outgrowth is still poorly understood. Neurite outgrowth is not sensitive to tetanus neurotoxin thus does not…”
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6
A novel tetanus neurotoxin-insensitive vesicle-associated membrane protein in SNARE complexes of the apical plasma membrane of epithelial cells
Published in Molecular biology of the cell (01-06-1998)“…The importance of soluble N-ethyl maleimide (NEM)-sensitive fusion protein (NSF) attachment protein (SNAP) receptors (SNAREs) in synaptic vesicle exocytosis is…”
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7
The small GTPase Rab13 regulates assembly of functional tight junctions in epithelial cells
Published in Molecular biology of the cell (01-06-2002)“…Junctional complexes such as tight junctions (TJ) and adherens junctions are required for maintaining cell surface asymmetry and polarized transport in…”
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8
Subcellular Localization of Tetanus Neurotoxin-Insensitive Vesicle-Associated Membrane Protein (VAMP)/VAMP7 in Neuronal Cells: Evidence for a Novel Membrane Compartment
Published in The Journal of neuroscience (15-11-1999)“…The clostridial neurotoxin-insensitive soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptors, tetanus neurotoxin-insensitive…”
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9
Expression, localization and functional role of small GTPases of the Rab3 family in insulin-secreting cells
Published in Journal of cell science (01-09-1996)“…We examined the presence of small molecular mass GTP-binding proteins of the Rab3 family in different insulin-secreting cells. Rab3B and Rab3C were identified…”
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Identification of Small GTP-Binding Rab Proteins in Human Platelets: Thrombin-Induced Phosphorylation of Rab3B, Rab6, and Rab8 Proteins
Published in Proceedings of the National Academy of Sciences - PNAS (15-08-1993)“…The activation of platelets by specific agonists is a tightly regulated mechanism that leads to the secretion of the dense- and α-granule contents. Platelets…”
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11
Insulin and okadaic acid induce Rab4 redistribution in adipocytes
Published in The Journal of biological chemistry (15-09-1993)“…Insulin stimulation of glucose transport involves the translocation of vesicles containing the glucose transporter Glut 4 to the plasma membrane. Rab proteins,…”
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12
The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking
Published in The Journal of cell biology (26-10-2015)“…Human immunodeficiency virus type 1 (HIV-1) impairs major functions of macrophages but the molecular basis for this defect remains poorly characterized. Here,…”
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13
Isoprenylation of Rab proteins possessing a C-terminal CaaX motif
Published in FEBS letters (20-09-1993)“…Rab proteins are small GTPases highly related to the yeast Ypti and Sec4 proteins involved in secretion. The Rab proteins were found associated with membranes…”
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14
MICAL-like1 in endosomal signaling
Published in Methods in enzymology (2014)“…Small GTPase Rabs are required for membrane protein sorting/delivery to precise membrane domains. Rab13 regulates tight junction assembly and polarized…”
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15
Tight junction: a co-ordinator of cell signalling and membrane trafficking
Published in Biology of the cell (01-08-2005)“…Increasing evidence indicates that the tight junction plays a role in membrane transport. Various signalling and trafficking molecules localize to the sites of…”
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16
Complete coding sequences of the ras related rab 3 and 4 cDNAs
Published in Nucleic acids research (11-02-1988)“…Partial nucleotide sequences of rab3 and rab4 cDNAs, isolated from a rat brain library, have been recently published. Here, the authors present their complete…”
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Differentiation of the epithelial apical junctional complex during mouse preimplantation development: a role for rab13 in the early maturation of the tight junction
Published in Mechanisms of development (01-10-2000)“…We have investigated the mechanisms by which the epithelial apicolateral junctional complex (AJC) is generated during trophectoderm differentiation in the…”
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18
Properties of Rab13 interaction with protein kinase A
Published in Methods in enzymology (2005)“…The small GTPase Rab13 localizes to tight junctions in epithelial cells and regulates the recruitment of claudin1 and ZO-1, two proteins required for the…”
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19
Chromosome assignment of four RAS-related RAB genes
Published in Human genetics (01-02-1991)“…The human RAB genes share structural and biochemical properties with the RAS gene superfamily. The encoded RAB proteins show 38 to 75% amino acid identity with…”
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Tight junctions, a platform regulating cell proliferation and polarity
Published in M.S. Médecine sciences (01-05-2004)“…Tight junctions (TJ) are specialized plasma membrane microdomains that encircle the apical pole of each epithelial and endothelial cell, separating apical from…”
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