Search Results - "Zahoor, A"
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Cofilin Mediates LPS-Induced Microglial Cell Activation and Associated Neurotoxicity Through Activation of NF-κB and JAK–STAT Pathway
Published in Molecular neurobiology (01-02-2018)“…Microglial cells are activated in response to different types of injuries or stress in the CNS. Such activation is necessary to get rid of the injurious agents…”
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2
Transcription Factors and Plants Response to Drought Stress: Current Understanding and Future Directions
Published in Frontiers in plant science (14-07-2016)“…Increasing vulnerability of plants to a variety of stresses such as drought, salt and extreme temperatures poses a global threat to sustained growth and…”
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3
Sustaining Protein Nutrition Through Plant-Based Foods
Published in Frontiers in nutrition (Lausanne) (18-01-2022)“…Proteins are essential components of the human diet. Dietary proteins could be derived from animals and plants. Animal protein, although higher in demand, is…”
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Inhibition of iron‐induced cofilin activation and inflammation in microglia by a novel cofilin inhibitor
Published in Journal of neurochemistry (18-11-2024)“…Abstract Neuroinflammatory conditions linked to iron dysregulation pose significant challenges in neurodegenerative diseases. Iron‐loaded microglia are…”
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Age-dependent sex differences in cofilin1 pathway (LIMK1/SSH1) and its association with AD biomarkers after chronic systemic inflammation in mice
Published in Neurobiology of aging (01-12-2024)“…Chronic systemic inflammation (CSI) results in neuroinflammation and neurodegeneration. Cofilin1 is a stress protein that activates microglia and induces…”
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Revisiting Alternaria-host interactions: New insights on its pathogenesis, defense mechanisms and control strategies
Published in Scientia horticulturae (01-12-2023)“…•Alternaria leaf blight is a serious problem in agriculture and horticulture.•Alternaria host interactions (pathogenesis, toxicity, immune response and…”
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The GSK3β inhibitor, TDZD-8, rescues cognition in a zebrafish model of okadaic acid-induced Alzheimer's disease
Published in Neurochemistry international (01-01-2019)“…Currently, no treatments exist that are able to directly treat against Alzheimer's disease (AD), and we are facing an inevitable increase in the near future of…”
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Intracerebral Hemorrhage and Diabetes Mellitus: Blood-Brain Barrier Disruption, Pathophysiology and Cognitive Impairments
Published in CNS & neurological disorders drug targets (01-01-2021)“…There is a surge in diabetes incidence, with an estimated 463 million individuals been diagnosed worldwide. Diabetes Mellitus (DM) is a major stroke-related…”
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Effect of cow manure biochar on maize productivity under sandy soil condition
Published in Soil use and management (01-06-2011)“…In this study, we performed a greenhouse experiment to investigate the effect of cow manure biochar on maize yield, nutrient uptake and physico‐chemical…”
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Ginkgo biloba prevents transient global ischemia-induced delayed hippocampal neuronal death through antioxidant and anti-inflammatory mechanism
Published in Neurochemistry international (01-01-2013)“…► EGb 761 shows antioxidant properties against tBCCAO-induced hippocampal cell death. ► The neuroprotective effects are partially through Nrf2/HO1 and VEGF…”
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Progress on siRNA-based gene therapy targeting secondary injury after intracerebral hemorrhage
Published in Gene therapy (01-02-2023)“…Intracerebral hemorrhage (ICH) is a life-threatening condition with a high mortality rate. For survivors, quality of life is determined by primary and…”
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12
Genomic Selection in the Era of Next Generation Sequencing for Complex Traits in Plant Breeding
Published in Frontiers in genetics (27-12-2016)“…Genomic selection (GS) is a promising approach exploiting molecular genetic markers to design novel breeding programs and to develop new markers-based models…”
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Recent advances in artificial intelligence, mechanistic models, and speed breeding offer exciting opportunities for precise and accelerated genomics‐assisted breeding
Published in Physiologia plantarum (01-07-2023)“…Given the challenges of population growth and climate change, there is an urgent need to expedite the development of high‐yielding stress‐tolerant crop…”
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Astrocytes in functional recovery following central nervous system injuries
Published in The Journal of physiology (01-07-2024)“…Astrocytes are increasingly recognised as partaking in complex homeostatic mechanisms critical for regulating neuronal plasticity following central nervous…”
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Cofilin Inhibition Restores Neuronal Cell Death in Oxygen–Glucose Deprivation Model of Ischemia
Published in Molecular neurobiology (01-03-2016)“…Ischemia is a condition associated with decreased blood supply to the brain, eventually leading to death of neurons. It is associated with a diverse cascade of…”
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16
Community structure, spatial distribution, diversity and functional characterization of culturable endophytic fungi associated with Glycyrrhiza glabra L
Published in Fungal biology (01-05-2019)“…A total of 266 endophytic fungal isolates were recovered from 1019 tissue segments of Glycyrrhiza glabra collected from four different locations in the…”
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Withania somnifera Improves Ischemic Stroke Outcomes by Attenuating PARP1-AIF-Mediated Caspase-Independent Apoptosis
Published in Molecular neurobiology (01-12-2015)“…Withania somnifera (WS), popularly known as “Ashwagandha” has been used for centuries as a nerve tonic. Its protective effect has been elucidated in many…”
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Development and validation of LC-MS/MS method for determining the metabolic stability, pharmacokinetics, and dose proportionality of a novel anti-inflammatory cofilin inhibitor
Published in Journal of pharmaceutical and biomedical analysis (20-03-2023)“…A novel small molecule cofilin inhibitor (SZ-3) has recently become the focus of investigation for targeting neuroinflammation in different neurodegenerative…”
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CRISPR/Cas approach: A new way of looking at plant-abiotic interactions
Published in Journal of plant physiology (01-05-2018)“…•CRISPR-Cas system has an immense potential for the development of specialized crops resilient to abiotic stress are discussed.•Besides, being efficient, easy…”
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Behavioural, genomics and proteomic approach to examine Alzheimer's disease in zebrafish
Published in Comparative biochemistry and physiology. Toxicology & pharmacology (01-09-2023)“…Globally around 24 million elderly population are dealing with dementia, and this pathological characteristic is commonly seen in people suffering from…”
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