Search Results - "Zahid, Saadia"

Ursolic acid and rosmarinic acid ameliorate alterations in hippocampal neurogenesis and social memory induced by amyloid beta in mouse model of Alzheimer's disease by Mirza, Fatima Javed, Zahid, Saadia

“…Alzheimer's disease (AD) is a multifaceted neurodegenerative disorder characterized by substantial neuronal damage which manifests in the form of deficits in…”
Get full text

An in silico approach to identify potential downstream targets of miR-153 involved in Alzheimer's disease by Amber, Sanila, Zahid, Saadia

“…In recent years, microRNAs (miRNAs) have emerged as key players in the pathophysiology of multiple diseases including Alzheimer's disease (AD). Messenger RNA…”
Get full text

Molecular Docking and Molecular Dynamics Studies Reveal Secretory Proteins as Novel Targets of Temozolomide in Glioblastoma Multiforme by Sumera, Anwer, Farha, Waseem, Maaz, Fatima, Areeba, Malik, Nishat, Ali, Amjad, Zahid, Saadia

“…Glioblastoma multiforme (GBM) is a tumor of glial origin and is the most malignant, aggressive and prevalent type, with the highest mortality rate in adult…”
Get full text

A quantitative meta-analysis of vitamin C in the pathophysiology of Alzheimer’s disease by Hamid, Maryam, Mansoor, Sumaiya, Amber, Sanila, Zahid, Saadia

“…Purpose Alzheimer’s disease (AD) is a multifaceted neurodegenerative disorder with many complex pathways feeding into its pathogenesis and progression. Vitamin…”
Get full text

Rosmarinus officinalis and Methylphenidate Exposure Improves Cognition and Depression and Regulates Anxiety-Like Behavior in AlCl3-Induced Mouse Model of Alzheimer’s Disease by Malik, Nishat, Amber, Sanila, Zahid, Saadia

“…Alzheimer’s disease (AD) is a neurological illness that causes severe cognitive impairment. AD patients also experience at least one of the neuropsychiatric…”
Get full text

Neuroprotective Effects of Carnosic Acid: Insight into Its Mechanisms of Action by Mirza, Fatima Javed, Zahid, Saadia, Holsinger, R M Damian

“…Carnosic acid is a diterpenoid abundantly present in plants belonging to the genus and of the family accounting for their application in traditional medicine…”
Get full text

Editorial: The role of natural products in neurological disorders by Tsolaki, Magda, Arcan, Chrisa, Zahid, Saadia

Get full text

Multitargeted Molecular Docking and Dynamic Simulation Studies of Bioactive Compounds from Rosmarinus officinalis against Alzheimer’s Disease by Mirza, Fatima Javed, Zahid, Saadia, Amber, Sanila, Sumera, Sumera, Jabeen, Hira, Asim, Noreen, Ali Shah, Syed Adnan

“…Alzheimer’s disease (AD) has been associated with the hallmark features of cholinergic dysfunction, amyloid beta (Aβ) aggregation and impaired synaptic…”
Get full text

Alterations in adult hippocampal neurogenesis, aberrant protein s-nitrosylation, and associated spatial memory loss in streptozotocin-induced diabetes mellitus type 2 mice by Noor, Aneeqa, Zahid, Saadia

“…Epidemiological and biochemical studies conducted over the past two decades have established a strong link between type 2 diabetes mellitus (T2DM) and…”
Get full text

The Geroprotective Drug Candidate CMS121 Alleviates Diabetes, Liver Inflammation, and Renal Damage in db/db Leptin Receptor Deficient Mice by Zahid, Saadia, Dafre, Alcir L, Currais, Antonio, Yu, Jingting, Schubert, David, Maher, Pamela

“…db/db mice, which lack leptin receptors and exhibit hyperphagia, show disturbances in energy metabolism and are a model of obesity and type 2 diabetes. The…”
Get full text

Effect of oxidative stress and calcium deregulation on FAM26F (CALHM6) expression during hepatitis B virus infection by Jabeen, Kehkshan, Malik, Uzma, Mansoor, Sajid, Shahzad, Shaheen, Zahid, Saadia, Javed, Aneela

“…Family with sequence similarity 26, member F (FAM26F) is an important innate immunity modulator playing a significant role in diverse immune responses,…”
Get full text

The neurogenic effects of rosmarinic acid in a mouse model of type 2 diabetes mellitus by Ali, Mahnoor, Zahid, Saadia

“…There is emerging evidence for a dysregulation of insulin signaling in the brains of patients with Alzheimer’s disease (AD) with overlapping molecular features…”
Get full text

Phosphoproteome profiling of substantia nigra and cortex regions of Alzheimer's disease patients by Zahid, Saadia, Oellerich, Michael, Asif, Abdul R, Ahmed, Nikhat

“…J. Neurochem. (2012) 121, 954–963. Alzheimer’s disease (AD) is the most common form of dementia and cognitive impairment usually characterized by widespread…”
Get full text

Differential Expression of Proteins in Brain Regions of Alzheimer’s Disease Patients by Zahid, Saadia, Oellerich, Michael, Asif, Abdul R., Ahmed, Nikhat

“…Alzheimer’s disease (AD), a progressive neurodegenerative disorder and the most common form of dementia and cognitive impairment is usually characterized by…”
Get full text

Methylphenidate and Rosmarinus officinalis improves cognition and regulates inflammation and synaptic gene expression in AlCl3-induced neurotoxicity mouse model by Khalid, Anibah, Abbasi, Umme Aimen, Amber, Sanila, Sumera, Mirza, Fatima Javed, Asif, Muhammad, Javed, Aneela, Zahid, Saadia

“…Methylphenidate (MPH), a psychotropic medication is commonly used for children with attention deficit hyperactivity disorder (ADHD). In this study we…”
Get full text

Syzygium aromaticum ethanol extract reduces AlCl3-induced neurotoxicity in mice brain through regulation of amyloid precursor protein and oxidative stress gene expression by Amber, Sanila, Ali Shah, Syed, Ahmed, Touqeer, Zahid, Saadia

“…Objective: To investigate the neuroprotective effects of Syzygium aromaticum (S. aromaticum) extract (500 mg/kg) on AlCl3 (300 mg/kg)-induced mouse model of…”
Get full text

Ameliorative effects of probiotics in AlCl3-induced mouse model of Alzheimer’s disease by Hamid, Maryam, Zahid, Saadia

“…In recent years, gut microbiome alterations have been linked with complex underlying mechanisms of neurodegenerative disorders including Alzheimer’s disease…”
Get full text

Ameliorative effects of probiotics in AlCl.sub.3-induced mouse model of Alzheimer's disease by Hamid, Maryam, Zahid, Saadia

“…In recent years, gut microbiome alterations have been linked with complex underlying mechanisms of neurodegenerative disorders including Alzheimer's disease…”
Get full text

The Role of Synapsins in Neurological Disorders by Mirza, Fatima Javed, Zahid, Saadia

“…Synapsins serve as flagships among the presynaptic proteins due to their abundance on synaptic vesicles and contribution to synaptic communication. Several…”
Get full text

A review of the role of synaptosomal-associated protein 25 (SNAP-25) in neurological disorders by Noor, Aneeqa, Zahid, Saadia

“…Synaptosomal-associated protein 25 kDa (SNAP-25) is one of the key proteins involved in the formation of neural soluble N-ethylmaleimide-sensitive factor…”
Get full text