Search Results - "Zahedi, René Peiman"
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Systematic and quantitative comparison of digest efficiency and specificity reveals the impact of trypsin quality on MS-based proteomics
Published in Journal of proteomics (02-02-2012)“…Trypsin is the most frequently used proteolytic enzyme in mass spectrometry-based proteomics. Beside its good availability, it also offers some major…”
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Highly Sensitive Phosphoproteomics by Tailoring Solid-Phase Extraction to Electrostatic Repulsion-Hydrophilic Interaction Chromatography
Published in Analytical chemistry (Washington) (03-02-2015)“…In the past decade, several strategies for comprehensive phosphoproteome analysis have been introduced. Most of them combine different phosphopeptide…”
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Catch me if you can: Mass spectrometry-based phosphoproteomics and quantification strategies
Published in Proteomics (Weinheim) (01-02-2011)“…Phosphorylation of proteins is one of the most prominent PTMs and for instance a key regulator of signal transduction. In order to improve our understanding of…”
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Multidimensional electrostatic repulsion–hydrophilic interaction chromatography (ERLIC) for quantitative analysis of the proteome and phosphoproteome in clinical and biomedical research
Published in Biochimica et biophysica acta (01-05-2015)“…Quantitative proteomics and phosphoproteomics have become key disciplines in understanding cellular processes. Fundamental research can be done using cell…”
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Differential proteomic comparison of breast cancer secretome using a quantitative paired analysis workflow
Published in BMC cancer (18-04-2019)“…Worldwide, breast cancer is the main cause of cancer mortality in women. Most cases originate in mammary ductal cells that produce the nipple aspirate fluid…”
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Assembly of nuclear pore complexes mediated by major vault protein
Published in Journal of cell science (15-03-2009)“…During interphase growth of eukaryotic cells, nuclear pore complexes (NPCs) are continuously incorporated into the intact nuclear envelope (NE) by mechanisms…”
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Biochemical and pathological changes result from mutated Caveolin-3 in muscle
Published in Skeletal muscle (28-08-2018)“…Caveolin-3 (CAV3) is a muscle-specific protein localized to the sarcolemma. It was suggested that CAV3 is involved in the connection between the extracellular…”
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Two-dimensional benzyldimethyl-n-hexadecylammonium chloride/SDS-PAGE for membrane proteomics
Published in Proteomics (Weinheim) (01-09-2005)Get full text
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Revealing phosphoproteins playing role in tobacco pollen activated in vitro
Published in Proteomics (Weinheim) (01-11-2012)“…The transition between the quiescent mature and the metabolically active germinating pollen grain most probably involves changes in protein phosphorylation…”
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Simultaneous Metabolite, Protein, Lipid Extraction (SIMPLEX): A Combinatorial Multimolecular Omics Approach for Systems Biology
Published in Molecular & cellular proteomics (01-04-2016)“…Interconnected molecular networks are at the heart of signaling pathways that mediate adaptive plasticity of eukaryotic cells. To gain deeper insights into the…”
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Comprehensive Mutational Analysis Reveals p6Gag Phosphorylation To Be Dispensable for HIV-1 Morphogenesis and Replication
Published in Journal of Virology (01-01-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Two‐dimensional benzyldimethyl‐n‐hexadecylammonium chloride/SDS‐PAGE for membrane proteomics
Published in Proteomics (Weinheim) (01-09-2005)“…Despite the importance of membranes in any living system, the global analysis of membrane subproteomes is still a common obstacle. In particular, the widely…”
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The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia
Published in Cell reports (Cambridge) (14-02-2017)“…Oxygen-dependent HIF1α hydroxylation and degradation are strictly controlled by PHD2. In hypoxia, HIF1α partly escapes degradation because of low oxygen…”
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Phosphoproteomics Profiling of Tobacco Mature Pollen and Pollen Activated in vitro
Published in Molecular & cellular proteomics (01-04-2016)“…Tobacco mature pollen has extremely desiccated cytoplasm, and is metabolically quiescent. Upon re-hydration it becomes metabolically active and that results in…”
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Myopathy in Marinesco–Sjögren syndrome links endoplasmic reticulum chaperone dysfunction to nuclear envelope pathology
Published in Acta neuropathologica (01-05-2014)“…Marinesco–Sjögren syndrome (MSS) features cerebellar ataxia, mental retardation, cataracts, and progressive vacuolar myopathy with peculiar myonuclear…”
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Recent advances in yeast organelle and membrane proteomics
Published in Proteomics (Weinheim) (01-10-2009)“…Yeast proteome research comprises two different aspects: with respect to systemic fungal infections (fungemias), invasive candidiasis, for instance by Candida…”
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Nuclear envelopes from amphibian oocytes — from morphology to protein inventory
Published in European journal of cell biology (01-03-2005)Get full text
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good, the bad, the ugly: Validating the mass spectrometric analysis of modified peptides
Published in Proteomics (Weinheim) (01-03-2011)“…Mass spectrometric characterization of protein modifications is usually based on single peptides. With the advent of large-scale PTM-focussed MS studies, vast…”
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The Human Platelet Membrane Proteome Reveals Several New Potential Membrane Proteins
Published in Molecular & cellular proteomics (01-11-2005)“…We present the first focused proteome study on human platelet membranes. Due to the removal of highly abundant cytoskeletal proteins a wide spectrum of known…”
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Comprehensive Mutational Analysis Reveals p6 Gag Phosphorylation To Be Dispensable for HIV-1 Morphogenesis and Replication
Published in Journal of virology (15-01-2013)“…The structural polyprotein Gag of human immunodeficiency virus type 1 (HIV-1) is necessary and sufficient for formation of virus-like particles. Its C-terminal…”
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