Comparison of bacteriolytic activity of human interleukin-2 and chicken egg lysozyme on Lactobacillus plantarum and Escherichia coli cells

The article continues studies of the recently discovered bacteriolytic activity of interleukin-2. It was detected earlier that interleukin (IL-2) possesses greater substrate specificity in comparison with chicken egg lysozyme. IL-2 disrupted the cell wall of Escherichia coli but did not lyse lysozym...

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Bibliographic Details
Published in:	Moscow University chemistry bulletin Vol. 70; no. 6; pp. 287 - 291
Main Authors:	Levashov, P. A., Matolygina, D. A., Osipova, H. E., Savin, S. S., Zaharova, G. S., Gasanova, D. A., Belogurova, N. G., Ovchinnikova, E. D., Smirnov, S. A., Tishkov, V. I., Levashov, A. V.
Format:	Journal Article
Language:	English
Published:	New York Allerton Press 01-11-2015
Subjects:	Chemistry Chemistry and Materials Science Chemistry/Food Science chicken egg lysozyme interleukin-2 bacteriolytic activity
Online Access:	Get full text
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Summary:	The article continues studies of the recently discovered bacteriolytic activity of interleukin-2. It was detected earlier that interleukin (IL-2) possesses greater substrate specificity in comparison with chicken egg lysozyme. IL-2 disrupted the cell wall of Escherichia coli but did not lyse lysozyme substrates such as the cell walls of Micrococcus luteus and Bacillus subtilis . In the present study it is demonstrated for the first time that both IL-2 and chicken egg lysozyme are capable of lysing Lactobacillus plantarum . The effects of IL-2 and chicken egg lysozyme on Lactobacillus plantarum are compared with those on Escherichia coli . The dependences of the rate of lysis on the concentration of bacteriolytic factors and pH are studied.
ISSN:	0027-1314 1935-0260
DOI:	10.3103/S0027131415060048