Search Results - "Zaharia, Oana P"

Role of Patatin-Like Phospholipase Domain-Containing 3 Gene for Hepatic Lipid Content and Insulin Resistance in Diabetes by Zaharia, Oana P, Strassburger, Klaus, Knebel, Birgit, Kupriyanova, Yuliya, Karusheva, Yanislava, Wolkersdorfer, Martin, Bódis, Kálmán, Markgraf, Daniel F, Burkart, Volker, Hwang, Jong-Hee, Kotzka, Jörg, Al-Hasani, Hadi, Szendroedi, Julia, Roden, Michael

“…The rs738409(G) single nucleotide polymorphism (SNP) in the patatin-like phospholipase domain-containing 3 ( ) gene associates with increased risk and…”
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Vitamin B12 and Folate Concentrations in Recent-onset Type 2 Diabetes and the Effect of Metformin Treatment by Kanti, Georgia, Anadol-Schmitz, Evrim, Bobrov, Pavel, Strassburger, Klaus, Kahl, Sabine, Zaharia, Oana P, Sarabhai, Theresia, Karusheva, Yanislava, Burkart, Volker, Markgraf, Daniel F, Trenkamp, Sandra, Ziegler, Dan, Szendroedi, Julia, Roden, Michael

“…Abstract Context Vitamin B12 and folate deficiency are not only linked to hematological, neurological, and cardiovascular diseases, but are also associated…”
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Comorbidities in Recent-Onset Adult Type 1 Diabetes: A Comparison of German Cohorts by Zaharia, Oana P., Lanzinger, Stefanie, Rosenbauer, Joachim, Karges, Wolfram, Müssig, Karsten, Meyhöfer, Sebastian M., Burkart, Volker, Hummel, Michael, Raddatz, Dirk, Roden, Michael, Szendroedi, Julia, Holl, Reinhard W.

“…Aims Restrictive exclusion criteria from different study populations may limit the generalizability of the observations. By comparing two differently designed…”
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Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study by Zaharia, Oana P, Strassburger, Klaus, Strom, Alexander, Bönhof, Gidon J, Karusheva, Yanislava, Antoniou, Sofia, Bódis, Kálmán, Markgraf, Daniel F, Burkart, Volker, Müssig, Karsten, Hwang, Jong-Hee, Asplund, Olof, Groop, Leif, Ahlqvist, Emma, Seissler, Jochen, Nawroth, Peter, Kopf, Stefan, Schmid, Sebastian M, Stumvoll, Michael, Pfeiffer, Andreas F H, Kabisch, Stefan, Tselmin, Sergey, Häring, Hans U, Ziegler, Dan, Kuss, Oliver, Szendroedi, Julia, Roden, Michael, Belgardt, Bengt-Frederik, Buyken, Anette, Eckel, Jürgen, Geerling, Gerd, Al-Hasani, Hadi, Herder, Christian, Hwang, Jong-Hee, Icks, Andrea, Kotzka, Jörg, Kuss, Oliver, Lammert, Eckart, Markgraf, Daniel, Müssig, Karsten, Rathmann, Wolfgang, Roden, Michael, Szendroedi, Julia, Ziegler, Dan

“…Cluster analyses have proposed different diabetes phenotypes using age, BMI, glycaemia, homoeostasis model estimates, and islet autoantibodies. We tested…”
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229-OR: Physical Fitness and Cardiovascular Risk Factors in Diabetes Subgroups by SAATMANN, NINA, ZAHARIA, OANA P., STRASSBURGER, KLAUS, PESTA, DOMINIK, BURKART, VOLKER, SZENDROEDI, JULIA, RODEN, MICHAEL

“…Physical inactivity promotes insulin resistance and increases the risk of diabetes and cardiovascular disease. Clustering based on simple clinical measures has…”
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432-P: Role of Patatin-Like Phospholipase Domain–Containing 3 Gene for Kidney Dysfunction in Diabetes Endotypes by ZAHARIA, OANA P., STRASSBURGER, KLAUS, KNEBEL, BIRGIT, KUPRIYANOVA, YULIYA, KOTZKA, JORG, BÓDIS, KÁLMÁN, SCHÖN, MARTIN, BOMBRICH, MARIA, MÖSER, CLARA, PRYSTUPA, KATSIARYNA, AL-HASANI, HADI, SCHRAUWEN-HINDERLING, VERA, JANDELEIT-DAHM, KARIN, WAGNER, ROBERT, RODEN, MICHAEL

“…Recent studies identified distinct endotypes of diabetes with differences in metabolic features and in risk for diabetes-related comorbidities. Of note,…”
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1573-P: Association of Thyroid Hormone Levels with NAFLD in Recent-Onset Diabetes by SAATMANN, NINA, SCHÖN, MARTIN, ZAHARIA, OANA P., HUTTASCH, MAXIMILIAN, STRASSBURGER, KLAUS, TRENKAMP, SANDRA, KUPRIYANOVA, YULIYA, SCHRAUWEN-HINDERLING, VERA, KAHL, SABINE, BURKART, VOLKER, WAGNER, ROBERT, RODEN, MICHAEL

“…Nonalcoholic fatty liver disease (NAFLD) is a growing health concern associated with obesity and type 2 diabetes (T2D). Thyroid hormones are important…”
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100-OR: Association of Recent Myocardial Infarction with Insulin Resistance and Fatty Liver Disease in Type 2 Diabetes by MÖSER, CLARA, ZAHARIA, OANA P., MICHLOTTI, FILIPPO C., KUPRIYANOVA, YULIYA, SCHRAUWEN-HINDERLING, VERA, BOBROV, PAVEL, BURKART, VOLKER, KELM, MALTE, SZENDROEDI, JULIA M., RODEN, MICHAEL

“…Insulin resistance and nonalcoholic fatty liver disease (NAFLD) frequently associate with type 2 diabetes (T2D) and cardiovascular disease and worsen their…”
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1325-P: Continuous Representation of Type 2 Diabetes Heterogeneity on a Tree-Like Graph Structure Stratifies Risk of Complications by SCHÖN, MARTIN, PRYSTUPA, KATSIARYNA, MORI, TIM, ZAHARIA, OANA P., BÓDIS, KÁLMÁN, KUPRIYANOVA, YULIYA, NAIR, ANAND, STROM, ALEXANDER, GUTHOFF, RAINER, BÖNHOF, GIDON J., BIRKENFELD, ANDREAS L., SEISSLER, JOCHEN, PFEIFFER, ANDREAS F., BLÜHER, MATTHIAS, BORNSTEIN, STEFAN R., SZENDROEDI, JULIA, MEYHOEFER, SVENJA, BURKART, VOLKER, SCHRAUWEN-HINDERLING, VERA, KUSS, OLIVER, PEARSON, EWAN, RODEN, MICHAEL, WAGNER, ROBERT

“…Heterogeneity in type 2 diabetes (T2D) can be represented by a tree-like structure using reverse graph-embedded dimensionality reduction. We aimed to validate…”
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1566-P: The TM6SF2 rs58542926 Polymorphism Dissociates Hepatocellular Lipids from Insulin Resistance in Recent-Onset Type 2 Diabetes by BÓDIS, KÁLMÁN, BOMBRICH, MARIA, SCHÖN, MARTIN, KNEBEL, BIRGIT, ZAHARIA, OANA P., BÖNHOF, GIDON J., KARUSHEVA, YANISLAVA, KUPRIYANOVA, YULIYA, KOTZKA, JORG, GUTHOFF, RAINER, SCHRAUWEN-HINDERLING, VERA, AL-HASANI, HADI, BURKART, VOLKER, SZENDROEDI, JULIA, WAGNER, ROBERT, MARKGRAF, DANIEL F., RODEN, MICHAEL

“…Increased hepatocellular lipid content (HCL) is generally linked to insulin resistance, which contributes to greater risk of type 2 diabetes and cardiovascular…”
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1452-P: Type 1 Diabetes Subphenotypes—A Cluster Analysis by PRYSTUPA, KATSIARYNA, FRITSCHE, ANDREAS, BÖNHOF, GIDON J., STROM, ALEXANDER, HENI, MARTIN, SEISSLER, JOCHEN, SZENDROEDI, JULIA, PFEIFFER, ANDREAS F., STUMVOLL, MICHAEL W., MEYHÖFER, SEBASTIAN M., ZAHARIA, OANA P., SAATMANN, NINA, HUTTASCH, MAXIMILIAN, STRASSBURGER, KLAUS, BURKART, VOLKER, RODEN, MICHAEL, WAGNER, ROBERT

“…Adult-onset type 1 diabetes (T1D) is a chronic disease with progressive beta-cell destruction. However, individuals with adult-onset T1D are metabolically…”
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211-LB: Branched-Chain Amino Acid Levels Negatively Associate with Postprandial ß-Cell Function in Type 1 Diabetes by KARUSHEVA, YANISLAVA, STRASSBURGER, KLAUS, MARKGRAF, DANIEL F., ZAHARIA, OANA P., BODIS, KALMAN, TURA, ANDREA, PACINI, GIOVANNI, BURKART, VOLKER, SZENDROEDI, JULIA, RODEN, MICHAEL

“…Understanding the role of insulin resistance (IR) in type 1 diabetes (T1D) may help to improve its treatment. Postprandial insulin secretion stimulates amino…”
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Metabolic Characteristics of Recently Diagnosed Adult-Onset Autoimmune Diabetes Mellitus by Zaharia, Oana P, Bobrov, Pavel, Strassburger, Klaus, Bódis, Kálmán, Karusheva, Yanislava, Scholz, Michaela, Markgraf, Daniel F, Burkart, Volker, Schloot, Nanette C, Müssig, Karsten, Szendroedi, Julia, Roden, Michael

“…Among patients diagnosed with type 2 diabetes, autoimmune diabetes often remains undetected. Metabolic features of these patients are insufficiently…”
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Diabetes clusters and risk of diabetes-associated diseases – Authors' reply by Zaharia, Oana P, Kuss, Oliver, Strassburger, Klaus, Burkart, Volker, Szendroedi, Julia, Roden, Michael

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81-OR: High Throughput Proteomics Identifies Neurofilament Light Chain (NFL) as a Novel Blood Biomarker for Detection of Diabetic Sensorimotor Polyneuropathy by MAALMI, HAIFA, STROM, ALEXANDER, HAUCK, STEFANIE M., ZAHARIA, OANA P., STRASSBURGER, KLAUS, BÖNHOF, GIDON J., RATHMANN, WOLFGANG, TRENKAMP, SANDRA, BURKART, VOLKER, SZENDROEDI, JULIA M., ZIEGLER, DAN, RODEN, MICHAEL, HERDER, CHRISTIAN

“…Background: The neurofilament light chain (NFL) is a polypeptide abundant in neuronal axons, reflecting ongoing neuroaxonal degeneration when detected in the…”
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1888-P: Impaired Insulin Clearance Relates to Increased Liver Fat Content in Recent-Onset Type 2 Diabetes and to Impaired Glucose Control in Recent-Onset Type 1 Diabetes by ANTONIOU, SOFIA, ZAHARIA, OANA P., STRASSBURGER, KLAUS, KARUSHEVA, YANISLAVA, BODIS, KALMAN, KUPRIYANOVA, YULIYA, BURKART, VOLKER, MUESSIG, KARSTEN, GASTALDELLI, AMALIA, RODEN, MICHAEL, SZENDROEDI, JULIA

“…Hepatic insulin metabolism in patients with newly diagnosed diabetes is not yet understood. Insulin clearance seems to be decreased in patients with obesity,…”
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325-OR: Early Parallel Progression of Peripheral and Cardiac Autonomic Nerve Dysfunction in Recent-Onset Type 1 Diabetes Patients by BÖNHOF, GIDON J., STROM, ALEXANDER, ZAHARIA, OANA P., SZENDROEDI, JULIA, MUESSIG, KARSTEN, RODEN, MICHAEL, ZIEGLER, DAN

“…We previously demonstrated an early parallel involvement of small and large fibers in recent-onset type 2 diabetes. Here we hypothesized that this pattern may…”
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1915-P: Targeting Remission of Type 2 Diabetes Using a Digital Education and Behavior Change Program Improves Insulin Sensitivity and Liver Fat Content in Type 2 Diabetes by PESTA, DOMINIK, ZAHARIA, OANA P., KUPRIYANOVA, YULIYA, HWANG, JONG-HEE, MARKGRAF, DANIEL F., TRENELL, MICHAEL, SZENDROEDI, JULIA, RODEN, MICHAEL

“…Recent controlled trials have demonstrated that type 2 diabetes (T2D) remission is possible with significant weight loss in people with newly diagnosed T2D…”
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Intramyocellular Triglyceride Content During the Early Course of Type 1 and Type 2 Diabetes by Schön, Martin, Zaharia, Oana P., Strassburger, Klaus, Kupriyanova, Yuliya, Bódis, Kálmán, Heilmann, Geronimo, Strom, Alexander, Bönhof, Gidon J., Michelotti, Filippo, Yurchenko, Iryna, Möser, Clara, Huttasch, Maximilian, Bombrich, Maria, Kelm, Malte, Burkart, Volker, Schrauwen-Hinderling, Vera B., Wagner, Robert, Roden, Michael, Roden, M., Al-Hasani, H., Belgardt, B., Bönhof, G.J., Burkart, V., Buyken, A.E., Geerling, G., Herder, C., Icks, A., Jandeleit-Dahm, K., Kotzka, J., Kuß, O., Lammert, E., Rathmann, W., Schrauwen-Hinderling, V., Szendroedi, J., Trenkamp, S., Wagner, R.

“…Intramyocellular lipid content (IMCL) is elevated in insulin-resistant humans, but it changes over time, and relationships with comorbidities remain unclear…”
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22-LB: Incident Myocardial Infarction Is Associated with Insulin Resistance and Liver Fibrosis Scores by M ÖSER, CLARA, ZAHARIA, OANA P., ROTHE, MAIK, HWANG, JONG-HEE, BOBROV, PAVEL, BURKART, VOLKER, B ÖNNER, FLORIAN, JUNG, CHRISTIAN, KELM, MALTE, RODEN, MICHAEL, SZENDROEDI, JULIA

“…Insulin resistance and nonalcoholic fatty liver disease associate with increased risk of cardiovascular disease and predict a worse outcome. The underlying…”
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