Search Results - "Zagrean, Leon"
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Melatonin's Impact on Antioxidative and Anti-Inflammatory Reprogramming in Homeostasis and Disease
Published in Biomolecules (Basel, Switzerland) (20-08-2020)“…There is a growing consensus that the antioxidant and anti-inflammatory properties of melatonin are of great importance in preserving the body functions and…”
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Multicellular Crosstalk Between Exosomes and the Neurovascular Unit After Cerebral Ischemia. Therapeutic Implications
Published in Frontiers in neuroscience (06-11-2018)“…Restorative strategies after stroke are focused on the remodeling of cerebral endothelial cells and brain parenchymal cells. The latter, i.e., neurons, neural…”
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The Anatomical and Functional Heterogeneity of the Mediodorsal Thalamus
Published in Brain sciences (01-09-2020)“…The mediodorsal nucleus (MD) represents just one piece of a complex relay structure situated within the brain, called the thalamus. MD is characterized by its…”
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Getting an Early Start in Understanding Perinatal Asphyxia Impact on the Cardiovascular System
Published in Frontiers in pediatrics (26-02-2020)“…Perinatal asphyxia (PA) is a burdening pathology with high short-term mortality and severe long-term consequences. Its incidence, reaching as high as 10 cases…”
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Cardioprotective Mechanisms of Interrupted Anesthetic Preconditioning with Sevoflurane in the Setting of Ischemia/Reperfusion Injury in Rats
Published in Applied sciences (01-02-2022)“…Background: Anesthetic preconditioning (AP) is known to mimic ischemic preconditioning. The purpose of this study was to investigate the effects of an…”
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Ethanol exposed maturing rat cerebellar granule cells show impaired energy metabolism and increased cell death after oxygen-glucose deprivation
Published in Neural regeneration research (01-03-2019)“…Alcohol, a widely abused drug, has deleterious effects on the immature nervous system. This study investigates the effect of chronic in vitro ethanol exposure…”
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Electrical Stimulation in the Claustrum Area Induces a Deepening of Isoflurane Anesthesia in Rat
Published in Brain sciences (01-11-2019)“…The role of the claustrum in consciousness and vigilance states was proposed more than two decades ago; however, its role in anesthesia is not yet understood,…”
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Correlation between Heart Rate Variability and Claustrum Stimulation – Hypothesis, Experimental Studies and Future Perspectives
Published in Revista română de cardiologie (01-09-2021)“…Heart rate variability (HRV) has long been associated with cardiovascular risk, especially after a myocardial infarction, but also in general. HRV reflects and…”
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Brain chondroitin/dermatan sulfate, from cerebral tissue to fine structure: extraction, preparation, and fully automated chip-electrospray mass spectrometric analysis
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2012)“…Chondroitin sulfate (CS) and dermatan sulfate (DS) glycosaminoglycans (GAGs) are covalently linked to proteins, building up a wide range of proteoglycans, with…”
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Reduced Interhemispheric Coherence after Cerebellar Vermis Output Perturbation
Published in Brain sciences (01-09-2020)“…Motor coordination and motor learning are well-known roles of the cerebellum. Recent evidence also supports the contribution of the cerebellum to the…”
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Compassion vs. empathy. Necessary distinctions in approaching medical care
Published in Revista medicală Română (30-09-2021)“…The incidence of the fatigue caused by medical care brings to attention the emotional reactions to suffering and their possible effects on caregivers. In this…”
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Towards an electroencephalographic measure of awareness based on the reactivity of oscillatory macrostates to hearing a subject's own name
Published in The European journal of neuroscience (01-03-2024)“…We proposed that the brain's electrical activity is composed of a sequence of alternating states with repeating topographic spectral distributions on scalp…”
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Free will – an approach from the perspective of neuroscience
Published in Practica medicală (2006) (30-09-2021)“…Free will designates the possibility of conscious and free choice of the subject, as well as his real possibility to act. The topic has a special medical and…”
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Burst-Suppression EEG Reactivity to Photic Stimulation-A Translational Biomarker in Hypoxic-Ischemic Brain Injury
Published in Biomolecules (Basel, Switzerland) (06-08-2024)“…The reactivity of an electroencephalogram (EEG) to external stimuli is impaired in comatose patients showing burst-suppression (BS) patterns following…”
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Behavioral and molecular effects of prenatal continuous light exposure in the adult rat
Published in Brain research (01-11-2016)“…Abstract Disruption of the maternal environment during pregnancy leads to behavioral changes and diseases in the adult offspring. To explore the influence of…”
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Reduced Interhemispheric Coherence in Cerebellar Kainic Acid-Induced Lateralized Dystonia
Published in Frontiers in neurology (23-11-2020)“…The execution of voluntary muscular activity is controlled by the primary motor cortex, together with the cerebellum and basal ganglia. The synchronization of…”
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Taurine and Its Derivatives: Analysis of the Inhibitory Effect on Platelet Function and Their Antithrombotic Potential
Published in Journal of clinical medicine (27-01-2022)“…Taurine is a semi-essential, the most abundant free amino acid in the human body, with a six times higher concentration in platelets than any other amino acid…”
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Effects of Exogenous Androgens on Platelet Activity and Their Thrombogenic Potential in Supraphysiological Administration: A Literature Review
Published in Journal of clinical medicine (04-01-2021)“…Anabolic androgenic steroids (AAS), simply called "androgens", represent the most widespread drugs used to enhance performance and appearance in a sporting…”
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THE DEFAULT EEG MACROSTATE REACTIVITY TO PHOTIC STIMULATION DEPENDS ON ANAESTHETIC DEPTH IN RATS
Published in IBRO neuroscience reports (01-10-2023)Get full text
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EEG REACTIVITY DURING DEEP ANESTHESIA IS INCREASED IN A RAT MODEL OF ABSENCE EPILEPSY
Published in IBRO neuroscience reports (01-10-2023)Get full text
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