Search Results - "Zagha, Edward"

Shaping the Cortical Landscape: Functions and Mechanisms of Top-Down Cortical Feedback Pathways by Zagha, Edward

“…Cortical feedback pathways are proposed to guide cognition and behavior according to context and goal-direction. At the cellular level, cortical feedback…”
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Addendum: Shaping the Cortical Landscape: Functions and Mechanisms of Top-Down Cortical Feedback Pathways by Zagha, Edward

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Motor cortex gates distractor stimulus encoding in sensory cortex by Zhang, Zhaoran, Zagha, Edward

“…Suppressing responses to distractor stimuli is a fundamental cognitive function, essential for performing goal-directed tasks. A common framework for the…”
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Movement and Performance Explain Widespread Cortical Activity in a Visual Detection Task by Salkoff, David B, Zagha, Edward, McCarthy, Erin, McCormick, David A

“…Abstract Recent studies in mice reveal widespread cortical signals during task performance; however, the various task-related and task-independent processes…”
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The largest group of superficial neocortical GABAergic interneurons expresses ionotropic serotonin receptors by Lee, SooHyun, Hjerling-Leffler, Jens, Zagha, Edward, Fishell, Gord, Rudy, Bernardo

“…A highly diverse population of neocortical GABAergic inhibitory interneurons has been implicated in multiple functions in information processing within…”
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Motor Cortex Feedback Influences Sensory Processing by Modulating Network State by Zagha, Edward, Casale, Amanda E., Sachdev, Robert N.S., McGinley, Matthew J., McCormick, David A.

“…Long-range corticocortical communication may have important roles in context-dependent sensory processing, yet we know very little about how these pathways…”
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K + Channels at the Axon Initial Segment Dampen Near-Threshold Excitability of Neocortical Fast-Spiking GABAergic Interneurons by Goldberg, Ethan M., Clark, Brian D., Zagha, Edward, Nahmani, Mark, Erisir, Alev, Rudy, Bernardo

“…Fast-spiking cells (FS cells) are a prominent subtype of neocortical GABAergic interneurons with important functional roles. Multiple FS cell properties are…”
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Kv3.3 Channels at the Purkinje Cell Soma Are Necessary for Generation of the Classical Complex Spike Waveform by Zagha, Edward, Lang, Eric J, Rudy, Bernardo

“…Voltage-gated potassium channel subunit Kv3.3 is prominently expressed in cerebellar Purkinje cells and is known to be important for cerebellar function, as…”
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Dendritic Kv3.3 potassium channels in cerebellar purkinje cells regulate generation and spatial dynamics of dendritic Ca2+ spikes by Zagha, Edward, Manita, Satoshi, Ross, William N, Rudy, Bernardo

“…Purkinje cell dendrites are excitable structures with intrinsic and synaptic conductances contributing to the generation and propagation of electrical…”
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Distribution of Kv3.3 potassium channel subunits in distinct neuronal populations of mouse brain by Chang, Su Ying, Zagha, Edward, Kwon, Elaine S., Ozaita, Andres, Bobik, Marketta, Martone, Maryann E., Ellisman, Mark H., Heintz, Nathaniel, Rudy, Bernardo

“…Kv3.3 proteins are pore‐forming subunits of voltage‐dependent potassium channels, and mutations in the gene encoding for Kv3.3 have recently been linked to…”
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Simulating Cortical Feedback Modulation as Changes in Excitation and Inhibition in a Cortical Circuit Model by Zagha, Edward, Murray, John D, McCormick, David A

“…Cortical feedback pathways are hypothesized to distribute context-dependent signals during flexible behavior. Recent experimental work has attempted to…”
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Erratum: Addendum: Shaping the Cortical Landscape: Functions and Mechanisms of Top-Down Cortical Feedback Pathways by Zagha, Edward

“…[This corrects the article DOI: 10.3389/fnsys.2020.00033.]…”
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Dorsolateral Striatum is a Bottleneck for Responding to Task-Relevant Stimuli in a Learned Whisker Detection Task in Mice by Zareian, Behzad, Lam, Angelina, Zagha, Edward

“…A learned sensory-motor behavior engages multiple brain regions, including the neocortex and the basal ganglia. How a target stimulus is detected by these…”
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DPP10 Modulates Kv4-mediated A-type Potassium Channels by Zagha, Edward, Ozaita, Andres, Chang, Su Ying, Nadal, Marcela S., Lin, Udele, Saganich, Michael J., McCormack, Tom, Akinsanya, Karen O., Qi, Shu Y., Rudy, Bernardo

“…A new member of a family of proteins characterized by structural similarity to dipeptidyl peptidase (DPP) IV known as DPP10 was recently identified and linked…”
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Neural control of brain state by Zagha, Edward, McCormick, David A

“…Highlights • Forebrain activity is characterized by rapid transitions between multiple states. • Brain state is controlled on multiple spatial and temporal…”
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Functional Localization of an Attenuating Filter within Cortex for a Selective Detection Task in Mice by Aruljothi, Krithiga, Marrero, Krista, Zhang, Zhaoran, Zareian, Behzad, Zagha, Edward

“…An essential feature of goal-directed behavior is the ability to selectively respond to the diverse stimuli in one's environment. However, the neural…”
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Mutational Analysis of the Repeated Open Reading Frames, ORFs 63 and 70 and ORFs 64 and 69, of Varicella-Zoster Virus by Sommer, M H, Zagha, E, Serrano, O K, Ku, C C, Zerboni, L, Baiker, A, Santos, R, Spengler, M, Lynch, J, Grose, C, Ruyechan, W, Hay, J, Arvin, A M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Goal-directed learning is multidimensional and accompanied by diverse and widespread changes in neocortical signaling by Marrero, Krista, Aruljothi, Krithiga, Delgadillo, Christian, Kabbara, Sarah, Swatch, Lovleen, Zagha, Edward

“…Abstract New tasks are often learned in stages with each stage reflecting a different learning challenge. Accordingly, each learning stage is likely mediated…”
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Waking State: Rapid Variations Modulate Neural and Behavioral Responses by McGinley, Matthew J., Vinck, Martin, Reimer, Jacob, Batista-Brito, Renata, Zagha, Edward, Cadwell, Cathryn R., Tolias, Andreas S., Cardin, Jessica A., McCormick, David A.

“…The state of the brain and body constantly varies on rapid and slow timescales. These variations contribute to the apparent noisiness of sensory responses at…”
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Competing Neural Ensembles in Motor Cortex Gate Goal-Directed Motor Output by Zagha, Edward, Ge, Xinxin, McCormick, David A.

“…Unit recordings in behaving animals have revealed the transformation of sensory to motor representations in cortical neurons. However, we still lack…”
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