Search Results - "Zaggia, Barbara"
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Validation of the prognostic role of the “Helsinki Score” in 225 cases of adrenocortical carcinoma
Published in Human pathology (01-04-2017)“…Adrenocortical carcinoma patient prognosis is extremely variable and poorly predictable. The newly introduced Helsinki Score is the first so far proposed…”
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Retrospective Evaluation of the Outcome of Open Versus Laparoscopic Adrenalectomy for Stage I and II Adrenocortical Cancer
Published in European urology (01-05-2010)“…Abstract Background Although there is consensus that laparoscopy is the standard of care for the resection of benign adrenal tumours, there is controversy…”
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Pitfalls in the diagnosis of adrenocortical tumors: a lesson from 300 consultation cases
Published in Human pathology (01-12-2015)“…Summary The correct pathologic classification of adrenocortical carcinoma (ACC) is relevant to establish an early therapeutic strategy of this rare malignancy…”
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Gemcitabine plus metronomic 5-fluorouracil or capecitabine as a second-/third-line chemotherapy in advanced adrenocortical carcinoma: a multicenter phase II study
Published in Endocrine-related cancer (01-06-2010)“…Adrenocortical carcinoma (ACC) is a rare neoplasm characterized by poor prognosis. First-line systemic treatments in advanced disease include mitotane, either…”
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Prospective evaluation of mitotane toxicity in adrenocortical cancer patients treated adjuvantly
Published in Endocrine-related cancer (01-12-2008)“…Toxicity of adjuvant mitotane treatment is poorly known; thus, our aim was to assess prospectively the unwanted effects of adjuvant mitotane treatment and…”
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Evaluation of Midnight Salivary Cortisol as a Predictor Factor for Common Carotid Arteries Intima Media Thickness in Patients with Clinically Inapparent Adrenal Adenomas
Published in International Journal of Endocrinology (01-01-2015)“…Purpose. The aim of the present study was to investigate the atherosclerotic vascular damage in a consecutive series of patients with AI and to correlate it…”
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Long-Term Outcomes of Adjuvant Mitotane Therapy in Patients With Radically Resected Adrenocortical Carcinoma
Published in The journal of clinical endocrinology and metabolism (01-04-2017)“…In 2007, a retrospective case-control study provided evidence that adjuvant mitotane prolongs recurrence-free survival (RFS) in patients with radically…”
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Practical treatment using mitotane for adrenocortical carcinoma
Published in Current opinion in endocrinology, diabetes, and obesity (01-06-2014)“…Description of novel findings about the mechanism of action of mitotane and its activity as an adjunctive postoperative measure, or for treatment of advanced…”
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Topoisomerase 2α and thymidylate synthase expression in adrenocortical cancer
Published in Endocrine-related cancer (01-07-2017)“…Topoisomerase II alpha (TOP2A) and thymidylate synthase (TS) are known prognostic parameters in several tumors and also predictors of efficacy of…”
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Effects of mitotane on the hypothalamic–pituitary–adrenal axis in patients with adrenocortical carcinoma
Published in European journal of endocrinology (01-10-2017)“…Objective Mitotane, a drug used to treat adrenocortical cancer (ACC), inhibits multiple enzymatic steps of adrenocortical steroid biosynthesis, potentially…”
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Influence of the CYP2B6 polymorphism on the pharmacokinetics of mitotane
Published in Pharmacogenetics and genomics (01-06-2013)“…OBJECTIVEThe aim of this study was to assess the potential impact of the pharmacogenetic variability of CYP2B6 and ABCB1 genes on the pharmacokinetics of…”
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Prognostic factors of overall survival of stage III or IV adrenocortical carcinomas (ACC): A multicenter ENS@T study
Published in Journal of clinical oncology (20-05-2014)“…Abstract only…”
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Growth hormone values after an oral glucose load do not add clinically useful information in patients with acromegaly on long-term somatostatin receptor ligand treatment
Published in Endocrine (01-02-2014)“…The optimal method of assessing GH status in acromegalic patients receiving medical therapy with somatostatin analogs (SSA) has been matter of debate. The aim…”
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The combined low-dose dexamethasone suppression corticotropin-releasing hormone test as a tool to rule out Cushing's syndrome
Published in European journal of endocrinology (01-11-2008)“…ObjectiveIt remains to be evaluated whether the combined low-dose dexamethasone suppression corticotropin-releasing hormone test (LDDST-CRH test) may add to…”
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Diagnosi e terapia del carcinoma corticosurrenalico
Published in L'Endocrinologo (01-02-2014)“…Sommario Il carcinoma corticosurrenalico (CCS) è un tumore raro e molto aggressivo. Al momento attuale non sono stati individuati approcci terapeutici…”
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Rapporto tra acromegalia e neoplasia: fantasia o realtà?
Published in L'Endocrinologo (01-03-2007)Get full text
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