Search Results - "Zafir, Ayesha"

Antioxidant potential of fluoxetine in comparison to Curcuma longa in restraint-stressed rats by Zafir, Ayesha, Banu, Naheed

“…Stress plays a potential role in the onset and exacerbation of depression. Chronic restraint stress in rats, and psychosocial stress in humans, is implicated…”
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In vivo antioxidant status: A putative target of antidepressant action by Zafir, Ayesha, Ara, Anjum, Banu, Naheed

“…Oxidative stress is a critical route of damage in various psychological stress-induced disorders, such as depression. Antidepressants are widely prescribed to…”
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O-GlcNAc Signaling in the Cardiovascular System by Ngoh, Gladys A, Facundo, Heberty T, Zafir, Ayesha, Jones, Steven P

“…Cardiovascular function is regulated at multiple levels. Some of the most important aspects of such regulation involve alterations in an ever-growing list of…”
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Protein O‐GlcNAcylation Is a Novel Cytoprotective Signal in Cardiac Stem Cells by Zafir, Ayesha, Readnower, Ryan, Long, Bethany W., McCracken, James, Aird, Allison, Alvarez, Alejandro, Cummins, Timothy D., Li, Qianhong, Hill, Bradford G., Bhatnagar, Aruni, Prabhu, Sumanth D., Bolli, Roberto, Jones, Steven P.

“…Clinical trials demonstrate the regenerative potential of cardiac stem cell (CSC) therapy in the postinfarcted heart. Despite these encouraging preliminary…”
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O-GlcNAcylation Negatively Regulates Cardiomyogenic Fate in Adult Mouse Cardiac Mesenchymal Stromal Cells by Zafir, Ayesha, Bradley, James A, Long, Bethany W, Muthusamy, Senthilkumar, Li, Qianhong, Hill, Bradford G, Wysoczynski, Marcin, Prabhu, Sumanth D, Bhatnagar, Aruni, Bolli, Roberto, Jones, Steven P

“…In both preclinical and clinical studies, cell transplantation of several cell types is used to promote repair of damaged organs and tissues. Nevertheless,…”
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A New Method to Stabilize C-Kit Expression in Reparative Cardiac Mesenchymal Cells by Wysoczynski, Marcin, Dassanayaka, Sujith, Zafir, Ayesha, Ghafghazi, Shahab, Long, Bethany W, Noble, Camille, DeMartino, Angelica M, Brittian, Kenneth R, Bolli, Roberto, Jones, Steven P

“…Cell therapy improves cardiac function. Few cells have been investigated more extensively or consistently shown to be more effective than c-kit sorted cells;…”
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Modulation of in vivo oxidative status by exogenous corticosterone and restraint stress in rats by Zafir, Ayesha, Banu, Naheed

“…Physical and psychological stressors not only enhance activity of the hypothalamo-pituitary-adrenocortical axis, but also cause oxidative damage by inducing an…”
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Induction of oxidative stress by restraint stress and corticosterone treatments in rats by Zafir, Ayesha, Banu, Naheed

“…Chronic exposure to psychological stress in humans and restraint stress in experimental animals results in increased oxidative stress and resultant tissue…”
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MicroRNA-539 Is Up-regulated in Failing Heart, and Suppresses O-GlcNAcase Expression by Muthusamy, Senthilkumar, DeMartino, Angelica M., Watson, Lewis J., Brittian, Kenneth R., Zafir, Ayesha, Dassanayaka, Sujith, Hong, Kyung U., Jones, Steven P.

“…Derangements in metabolism and related signaling pathways characterize the failing heart. One such signal, O-linked β-N-acetylglucosamine (O-GlcNAc), is an…”
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Abstract 25: A Streamlined Technique to Stabilize C-kit Expression in Cardiac Mesenchymal Cells by Dassanayaka, Sujith, Long, Bethany W, Zafir, Ayesha, Ghafghazi, Shahab, Hunt, Gregory N, Noble, Camille T, DeMartino, Angelica M, Brittian, Kenneth R, Jones, Steven P, Wysoczynski, Marcin

“…Abstract only Adoptive transfer of various reparative cells attenuates cardiac dysfunction in preclinical models of heart failure. Although c-kit sorted cells…”
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Protein O‐GlcNAcylation – A Novel Cell Survival Signal in Cardiac Stem Cells by Zafir, Ayesha, Li, Qianhong, Bolli, Roberto, Jones, Steven P.

“…Abstract only Background Clinical trials demonstrate the potential efficacy of stem/progenitor cell therapy in the post‐infarcted heart. Yet, the basic biology…”
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Protein O‐GlcNAcylation Exerts Mitogenic Effects in Cardiac Progenitor Cells by Zafir, Ayesha, Li, Qianhong, Bolli, Roberto, Jones, Steven P

“…Background The limited reparative ability of CPCs requires innovative approaches. Here, we report the necessity of the cardioprotective stress signal ‐…”
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Protein O‐GlcNAcylation Promotes Post‐hypoxic Survival of Cardiac Progenitor Cells by Zafir, Ayesha, Li, Qianhong, Bolli, Roberto, Jones, Steven P

“…Background Cardiac progenitor cells (CPCs) represent a viable route to promote post‐infarct cardiac repair. We hypothesized that the auto‐protective stress…”
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Invivo antioxidant status: a putative target of antidepressant action by Zafir, Ayesha, Ara, Anjum, Banu, Naheed

“…Oxidative stress is a critical route of damage in various psychological stress-induced disorders, such as depression. Antidepressants are widely prescribed to…”
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O‐GlcNAc Signaling Regulates Cardiomyogenesis of Cardiac Progenitor Cells by Zafir, Ayesha, Hamid, Tariq, Hill, Bradford, Powell, David, Li, Qianhong, Bolli, Roberto, Jones, Steven P

“…Background Cardiac progenitor cells (CPCs) possess inherent, though poorly understood, reparative capabilities that may be important in the setting of…”
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Remedial antioxidant action of Withania somnifera on restraint stress‐induced oxidative damage by Al‐Qirim, Tariq Musbah, Zafir, Ayesha, Banu, Naheed

“…Abstract only Restraint stress is known to produce chronic physical and emotional stress, with impaired antioxidant defenses playing a key role at the…”
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Comparative anti‐oxidant potential of Rauwolfia serpentina and Withania somnifera on cardiac tissues by Al‐Qirim, Tariq Musbah, Zafir, Ayesha, Banu, Naheed

“…Herbal supplements have been shown to be effective in the management of cardiac illness, potentially by altering antioxidant defense capacity. Rauwolfia…”
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