Search Results - "Zaenker, Kurt S"

Neutrophil granulocytes promote the migratory activity of MDA-MB-468 human breast carcinoma cells via ICAM-1 by Strell, Carina, Lang, Kerstin, Niggemann, Bernd, Zaenker, Kurt S., Entschladen, Frank

“…Tumor infiltrating neutrophil granulocytes do not only exhibit tumor eliminating functions but also promote tumor progression. We have recently shown that…”
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Targeted Intraoperative Radiotherapy Impairs the Stimulation of Breast Cancer Cell Proliferation and Invasion Caused by Surgical Wounding by BELLETTI, Barbara, VAIDYA, Jayant S, VERONESI, Andrea, CANZONIERI, Vincenzo, TROVO, Mauro G, ZAENKER, Kurt S, COLOMBATTI, Alfonso, BALDASSARRE, Gustavo, MASSARUT, Samuele, D'ANDREA, Sara, ENTSCHLADEN, Frank, RONCADIN, Mario, LOVAT, Francesca, BERTON, Stefania, PERIN, Tiziana, CANDIANI, Ezio, RECCANELLO, Sonia

“…Purpose: After apparently successful excision of breast cancer, risk of local recurrence remains high mainly in the area surrounding the original tumor,…”
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Lipopolysaccharide (LPS) Promotes Apoptosis in Human Breast Epithelial × Breast Cancer Hybrids, but Not in Parental Cells by Fried, Sabrina, Tosun, Songuel, Troost, Gabriele, Keil, Silvia, Zaenker, Kurt S, Dittmar, Thomas

“…Toll-like receptors (TLRs) belong to the group of pathogen recognition receptors known to play a crucial role in the innate immune system. In cancer, TLR…”
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Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs by Lang, Kerstin, Drell, Theodore L., Lindecke, Antje, Niggemann, Bernd, Kaltschmidt, Christian, Zaenker, Kurt S., Entschladen, Frank

“…The active migration of tumor cells, a crucial requirement for metastasis development and cancer progression, is regulated by signal substances including…”
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Functional dichotomy of plasmacytoid dendritic cells: Antigen-specific activation of T cells versus production of type I interferon by Jaehn, Peter S, Zaenker, Kurt S, Schmitz, Juergen, Dzionek, Andrzej

“…Human plasmacytoid dendritic cells (PDC) are believed to link innate and adaptive immunity by producing type I interferon (IFN-I) and triggering adaptive T…”
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Enhanced Dendritic Cell-Induced Immune Responses Mediated by the Novel C-Type Lectin Receptor mDCAR1 by Kaden, Stefan A, Kurig, Stefanie, Vasters, Katrin, Hofmann, Kay, Zaenker, Kurt S, Schmitz, Juergen, Winkels, Gregor

“…The dendritic cell (DC) immunoreceptors (DCIR) and DC-immunoactivating receptors (DCAR) represent a subfamily of cell surface C-type lectin receptors (CLR),…”
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The cancer's nervous tooth: Considering the neuronal crosstalk within tumors by Entschladen, Frank, Palm, Daniel, Niggemann, Bernd, Zaenker, Kurt S

“…Abstract The nervous system is a superordinate organ in the body that controls the function of virtually all other organs and tissues. In the past, the role of…”
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Lipopolysaccharide Promotes Apoptosis in Human Breast Epithelial x Breast Cancer Hybrids, but Not in Parental Cells by Fried, Sabrina, Tosun, Songuel, Troost, Gabriele, Keil, Silvia, Zaenker, Kurt S, Dittmar, Thomas

“…Toll-like receptors (TLRs) belong to the group of pathogen recognition receptors known to play a crucial role in the innate immune system. In cancer, TLR…”
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Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells by Zhao, Wanzhou, Entschladen, Frank, Liu, Hongyan, Niggemann, Bernd, Fang, Qicheng, Zaenker, Kurt S, Han, Rui

“…The aim of the study was to investigate the antitumor and/or preventive effect of BC-4, an isomeric compound isolated from the plant Boswellia carteri Birdw…”
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Immunotherapy of Melanoma Targeting Human High Molecular Weight Melanoma-Associated Antigen: Potential Role of Nonimmunological Mechanisms by CHANG, CHIEN-CHUNG, CAMPOLI, MICHAEL, LUO, WEI, ZHAO, WANZHOU, ZAENKER, KURT S., FERRONE, SOLDANO

“…: Induction of humoral anti‐human high molecular weight melanoma‐associated antigen (anti‐HMW‐MAA) immunity following active specific immunotherapy is…”
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Emerging Role of IL-4–Induced Gene 1 as a Prognostic Biomarker Affecting the Local T-Cell Response in Human Cutaneous Melanoma by Ramspott, Jan Philipp, Bekkat, Fériel, Bod, Lloyd, Favier, Maryline, Terris, Benoit, Salomon, Anne, Djerroudi, Lounes, Zaenker, Kurt S., Richard, Yolande, Molinier-Frenkel, Valérie, Castellano, Flavia, Avril, Marie-Françoise, Prévost-Blondel, Armelle

“…Several studies have emphasized the importance of immune composition of the melanoma microenvironment for clinical outcome. The contribution of IL4I1, a…”
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Phosphatidylinositol 3-Kinase in the G Protein-Coupled Receptor–Induced Chemokinesis and Chemotaxis of MDA-MB-468 Breast Carcinoma Cells: A Comparison with Leukocytes by Bastian, Philipp, Posch, Birte, Lang, Kerstin, Niggemann, Bernd, Zaenker, Kurt S, Hatt, Hanns, Entschladen, Frank

“…The polarization of tumor cells and leukocytes into a front end and a rear end is a crucial prerequisite for their autonomous, directed movement…”
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The norepinephrine‐driven metastasis development of PC‐3 human prostate cancer cells in BALB/c nude mice is inhibited by β‐blockers by Palm, Daniel, Lang, Kerstin, Niggemann, Bernd, Drell, Theodore L., Masur, Kai, Zaenker, Kurt S., Entschladen, Frank

“…The development of metastases is a decisive step in the course of a cancer disease. The detection of metastases in cancer patients is correlated with a poor…”
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Tumour-cell migration, invasion, and metastasis: navigation by neurotransmitters by Entschladen, Frank, Drell, 4th, Theodore L, Lang, Kerstin, Joseph, Jan, Zaenker, Kurt S

“…Cancer starts as a localised disease, which, if detected early, can often be treated successfully by removal of the primary tumour. A pernicious progression is…”
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Sweetness in the enigmatic life of cancer cells by Zaenker, Kurt S

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Fusion in cancer: an explanatory model for aneuploidy, metastasis formation, and drug resistance by Mohr, Marieke, Zaenker, Kurt S, Dittmar, Thomas

“…Aneuploidy, metastasis formation, and drug resistance are major issues to overcome in most cancers. If there exists common underlying proceedings for the…”
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c‐erbB‐2/EGFR as dominant heterodimerization partners determine a motogenic phenotype in human breast cancer cells by Brandt, Burkhard H., Roetger, Antje, Dittmar, Thomas, Nikolai, Gerd, Seeling, Matthes, Merschjann, Anja, Nofer, Jerzy‐Roch, Dehmer‐Möller, Gunda, Junker, Ralf, Assmann, Gerd, Zaenker, Kurt S.

“…ABSTRACTSeparate mechanisms for oncogenesis and metastasis have been postulated. We show here that prolonged and invasive cell migration, a key mechanism in…”
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Adhesion molecules and chemokines: the navigation system for circulating tumor (stem) cells to metastasize in an organ-specific manner by Dittmar, Thomas, Heyder, Christoph, Gloria-Maercker, Eva, Hatzmann, Wolfgang, Zänker, Kurt S.

“…To date, cancer is still the second most prevalent cause of death after cardiovascular diseases in the industrialized word, whereby the primary cause of cancer…”
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Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes by JOSEPH, Jan, NIGGEMANN, Bernd, ZAENKER, Kurt S, ENTSCHLADEN, Frank

“…Cell migration is of paramount importance in physiological processes such as immune surveillance, but also in the pathological processes of tumor cell…”
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Double-stranded RNA induces S100 gene expression by a cycloheximide-sensitive factor by Voss, Andreas, Gescher, Kirsten, Hensel, Andreas, Nacken, Wolfgang, Zänker, Kurt S., Kerkhoff, Claus

“…► S100A8/A9 gene induction in keratinocytes by TLR3 ligand polyI:C. ► Confirmation in organotypic epithelial “raft” culture after herpes simplex virus…”
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