Search Results - "Zaeck, Luca M."

Comparative pathogenesis of different phylogroup I bat lyssaviruses in a standardized mouse model by Klein, Antonia, Eggerbauer, Elisa, Potratz, Madlin, Zaeck, Luca M, Calvelage, Sten, Finke, Stefan, Müller, Thomas, Freuling, Conrad M

“…A plethora of bat-associated lyssaviruses potentially capable of causing the fatal disease rabies are known today. Transmitted via infectious saliva,…”
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Innate Immune Signaling and Role of Glial Cells in Herpes Simplex Virus- and Rabies Virus-Induced Encephalitis by Feige, Lena, Zaeck, Luca M, Sehl-Ewert, Julia, Finke, Stefan, Bourhy, Hervé

“…The environment of the central nervous system (CNS) represents a double-edged sword in the context of viral infections. On the one hand, the infectious route…”
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Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses by Scheibner, David, Salaheldin, Ahmed H, Bagato, Ola, Zaeck, Luca M, Mostafa, Ahmed, Blohm, Ulrike, Müller, Christin, Eweas, Ahmed F, Franzke, Kati, Karger, Axel, Schäfer, Alexander, Gischke, Marcel, Hoffmann, Donata, Lerolle, Solène, Li, Xuguang, Abd El-Hamid, Hatem S, Veits, Jutta, Breithaupt, Angele, Boons, Geert-Jan, Matrosovich, Mikhail, Finke, Stefan, Pleschka, Stephan, Mettenleiter, Thomas C, de Vries, Robert P, Abdelwhab, Elsayed M

“…Global spread and regional endemicity of H5Nx Goose/Guangdong avian influenza viruses (AIV) pose a continuous threat for poultry production and zoonotic,…”
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Genetic and Antigenetic Characterization of the Novel Kotalahti Bat Lyssavirus (KBLV) by Calvelage, Sten, Tammiranta, Niina, Nokireki, Tiina, Gadd, Tuija, Eggerbauer, Elisa, Zaeck, Luca M, Potratz, Madlin, Wylezich, Claudia, Höper, Dirk, Müller, Thomas, Finke, Stefan, Freuling, Conrad M

“…There is a growing diversity of bat-associated lyssaviruses in the Old World. In August 2017, a dead Brandt's bat ( ) tested positive for rabies and based on…”
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Light Sheet Microscopy-Assisted 3D Analysis of SARS-CoV-2 Infection in the Respiratory Tract of the Ferret Model by Zaeck, Luca M, Scheibner, David, Sehl, Julia, Müller, Martin, Hoffmann, Donata, Beer, Martin, Abdelwhab, Elsayed M, Mettenleiter, Thomas C, Breithaupt, Angele, Finke, Stefan

“…The visualization of viral pathogens in infected tissues is an invaluable tool to understand spatial virus distribution, localization, and cell tropism in…”
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Chlamydia trachomatis Cell-to-Cell Spread through Tunneling Nanotubes by Jahnke, Rico, Matthiesen, Svea, Zaeck, Luca M, Finke, Stefan, Knittler, Michael R

“…Tunneling nanotubes (TNTs) are transient cellular connections that consist of dynamic membrane protrusions. They play an important role in cell-to-cell…”
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Analysis of Nipah Virus Replication and Host Proteome Response Patterns in Differentiated Porcine Airway Epithelial Cells Cultured at the Air-Liquid Interface by Müller, Martin, Fischer, Kerstin, Woehnke, Elisabeth, Zaeck, Luca M, Prönnecke, Christoph, Knittler, Michael R, Karger, Axel, Diederich, Sandra, Finke, Stefan

“…Respiratory tract epithelium infection plays a primary role in Nipah virus (NiV) pathogenesis and transmission. Knowledge about infection dynamics and host…”
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Potential determinants of the decline in mpox cases in Belgium: A behavioral, epidemiological and seroprevalence study by De Vos, Elise, Van Gestel, Liesbeth, Brosius, Isabel, Kenyon, Chris, Vuylsteke, Bea, De Baetselier, Irith, Mariën, Joachim, Bangwen, Eugene, Couvreur, Simon, Lecompte, Amaryl, Van Beckhoven, Dominique, Hoorelbeke, Bart, Verstrepen, Babs E., Zaeck, Luca M., de Vries, Rory D., Geurts van Kessel, Corine H., Hens, Niel, Ariën, Kevin K., Vercauteren, Koen, Van Esbroek, Marjan, Van Dijck, Christophe, Liesenborghs, Laurens

“…•Integrated data sources reveal insights into 2022s mpox epidemic decline.•Mpox first affected individuals with high-, then with lower-risk sexual…”
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Point Mutations in the Glycoprotein Ectodomain of Field Rabies Viruses Mediate Cell Culture Adaptation through Improved Virus Release in a Host Cell Dependent and Independent Manner by Nitschel, Sabine, Zaeck, Luca M, Potratz, Madlin, Nolden, Tobias, Te Kamp, Verena, Franzke, Kati, Höper, Dirk, Pfaff, Florian, Finke, Stefan

“…Molecular details of field rabies virus (RABV) adaptation to cell culture replication are insufficiently understood. A better understanding of adaptation may…”
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Role of Vesicle-Associated Membrane Protein-Associated Proteins (VAP) A and VAPB in Nuclear Egress of the Alphaherpesvirus Pseudorabies Virus by Dorsch, Anna D., Hölper, Julia E., Franzke, Kati, Zaeck, Luca M., Mettenleiter, Thomas C., Klupp, Barbara G.

“…The molecular mechanism affecting translocation of newly synthesized herpesvirus nucleocapsids from the nucleus into the cytoplasm is still not fully…”
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Analyzing the immunogenicity of bivalent booster vaccinations in healthcare workers: The SWITCH ON trial protocol by Tan, Ngoc H, Sablerolles, Roos S G, Rietdijk, Wim J R, Goorhuis, Abraham, Postma, Douwe F, Visser, Leo G, Bogers, Susanne, Geers, Daryl, Zaeck, Luca M, Koopmans, Marion P G, Dalm, Virgil A S H, Kootstra, Neeltje A, Huckriede, Anke L W, van Baarle, Debbie, Lafeber, Melvin, GeurtsvanKessel, Corine H, de Vries, Rory D, van der Kuy, Paul-Hugo Marie

“…Vaccination against coronavirus disease 2019 (COVID-19) has contributed greatly to providing protection against severe disease, thereby reducing hospital…”
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Comparable Long-Term Rabies Immunity in Foxes after IntraMuscular and Oral Application Using a Third-Generation Oral Rabies Virus Vaccine by Te Kamp, Verena, Friedrichs, Virginia, Freuling, Conrad M, Vos, Ad, Potratz, Madlin, Klein, Antonia, Zaeck, Luca M, Eggerbauer, Elisa, Schuster, Peter, Kaiser, Christian, Ortmann, Steffen, Kretzschmar, Antje, Bobe, Katharina, Knittler, Michael R, Dorhoi, Anca, Finke, Stefan, Müller, Thomas

“…The live genetically-engineered oral rabies virus (RABV) variant SPBN GASGAS induces long-lasting immunity in foxes and protection against challenge with an…”
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Low levels of monkeypox virus-neutralizing antibodies after MVA-BN vaccination in healthy individuals by Zaeck, Luca M., Lamers, Mart M., Verstrepen, Babs E., Bestebroer, Theo M., van Royen, Martin E., Götz, Hannelore, Shamier, Marc C., van Leeuwen, Leanne P. M., Schmitz, Katharina S., Alblas, Kimberley, van Efferen, Suzanne, Bogers, Susanne, Scherbeijn, Sandra, Rimmelzwaan, Guus F., van Gorp, Eric C. M., Koopmans, Marion P. G., Haagmans, Bart L., GeurtsvanKessel, Corine H., de Vries, Rory D.

“…In July 2022, the ongoing monkeypox (MPX) outbreak was declared a public health emergency of international concern. Modified vaccinia Ankara—Bavarian Nordic…”
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The implications of mpox breakthrough infections on future vaccination strategies by Shamier, Marc C, Zaeck, Luca M, de Vries, Rory D, GeurtsvanKessel, Corine H

“…More than 88 000 laboratory-confirmed human monkeypoxvirus (hMPXV) infections were reported in the 2022–23 global mpox (formerly known as monkeypox) outbreak,…”
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TGF-β/IFN-γ Antagonism in Subversion and Self-Defense of Phase II Coxiella burnetii - Infected Dendritic Cells by Matthiesen, Svea, Christiansen, Bahne, Jahnke, Rico, Zaeck, Luca M, Karger, Axel, Finke, Stefan, Franzke, Kati, Knittler, Michael R

“…Dendritic cells (DCs) belong to the first line of innate defense and come into early contact with invading pathogens, including the zoonotic bacterium Coxiella…”
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COVID-19 vaccine effectiveness and evolving variants: understanding the immunological footprint by Zaeck, Luca M, GeurtsvanKessel, Corine H, de Vries, Rory D

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Monkeypox Virus Cross-Neutralizing Antibodies in Clinical Trial Participants Vaccinated With Modified Vaccinia Virus Ankara Encoding Middle East Respiratory Syndrome–Coronavirus Spike Protein by Raadsen, Matthijs P, Dahlke, Christine, Fathi, Anahita, Lamers, Mart M, van den Doel, Petra, Zaeck, Luca M, van Royen, Martin E, de Bruin, Erwin, Sikkema, Reina, Koopmans, Marion, van Gorp, Eric C M, Sutter, Gerd, de Vries, Rory D, Addo, Marylyn M, Haagmans, Bart L

“…Abstract Modified vaccinia virus Ankara (MVA) is used as a vaccine against monkeypox virus and as a viral vaccine vector. MVA-MERS-S is a vaccine candidate…”
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Polysaccharide, Conjugate, and mRNA-based Vaccines are Immunogenic in Patients with Netherton Syndrome by Nouwen, Anouk E. M., Zaeck, Luca M., Schappin, Renske, Geers, Daryl, Gommers, Lennert, Bogers, Susanne, Dik, Willem A., Pasmans, Suzanne G. M. A., GeurtsvanKessel, Corine H., de Vries, Rory D., Dalm, Virgil A. S. H.

“…Background Netherton syndrome (NS) is a rare, severe genetic skin disorder, currently classified as an inborn error of immunity (IEI) due to previously…”
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Neuroglia infection by rabies virus after anterograde virus spread in peripheral neurons by Potratz, Madlin, Zaeck, Luca M, Weigel, Carlotta, Klein, Antonia, Freuling, Conrad M, Müller, Thomas, Finke, Stefan

“…The highly neurotropic rabies virus (RABV) enters peripheral neurons at axon termini and requires long distance axonal transport and trans-synaptic spread…”
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Profiling the SARS-CoV-2-specific T-cell response by Geers, Daryl, Gommers, Lennert, Tan, Ngoc H, Bogers, Susanne, van Baarle, Debbie, Grifoni, Alba, Sette, Alessandro, Boerma, Annemarie, Visscher, Frederique, Richard, Mathilde, Funk, Mathis, Zaeck, Luca M, van der Kuy, P Hugo M, Haagmans, Bart L, Koopmans, Marion PG, GeurtsvanKessel, Corine H, de Vries, Rory D

“…Small volumes of whole blood were stimulated with commercially available overlapping peptide pools covering the S protein from 12 different coronaviruses: nine…”
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