Search Results - "Zadinová, Marie"

Anti-cancer effects of blue-green alga Spirulina platensis, a natural source of bilirubin-like tetrapyrrolic compounds by Koníčková, Renata, Vaňková, Kateřina, Vaníková, Jana, Vánová, Katerina, Muchová, Lucie, Subhanová, Iva, Zadinová, Marie, Zelenka, Jaroslav, Dvořák, Ales, Kolář, Michal, Strnad, Hynek, Rimpelová, Silvie, Ruml, Tomas, Wong, Ronald J, Vítek, Libor

“…AbstractSpirulina platensis is a blue-green alga used as a dietary supplement because of its hypocholesterolemic properties. Among other bioactive substances,…”
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Differences in antitumor effects of various statins on human pancreatic cancer by Gbelcová, Helena, Leníček, Martin, Zelenka, Jaroslav, Knejzlík, Zdeněk, Dvořáková, Gabriela, Zadinová, Marie, Poučková, Pavla, Kudla, Michal, Balaž, Peter, Ruml, Tomáš, Vítek, Libor

“…Statins are widely used for the treatment of hypercholesterolemia. However, their inhibitory action on HMG‐CoA reductase also results in the depletion of…”
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Highly sensitive method for quantitative determination of bilirubin in biological fluids and tissues by Zelenka, Jaroslav, Leníček, Martin, Muchová, Lucie, Jirsa, Milan, Kudla, Michal, Balaž, Peter, Zadinová, Marie, Ostrow, J. Donald, Wong, Ronald J., Vítek, Libor

“…Unconjugated bilirubin (UCB) exhibits potent antioxidant and cytoprotective properties, but causes apoptosis and cytotoxicity at pathologically elevated…”
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Hydrogels based on low-methoxyl amidated citrus pectin and flaxseed gum formulated with tripeptide glycyl-l-histidyl-l-lysine improve the healing of experimental cutting wounds in rats by Synytsya, Alla, Poučková, Pavla, Zadinová, Marie, Troshchynska, Yana, Štětina, Jiří, Synytsya, Andriy, Saloň, Ivan, Král, Vladimír

“…Hydrogels based on natural and modified polysaccharides represent growing group of suitable matrices for the construction of effective wound healing materials…”
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Hyperbilirubinemia Protects against Aging-Associated Inflammation and Metabolic Deterioration by Haluzík, Martin, Zadinová, Marie, Alán, Lukáš, Dvořák, Aleš, Zelenka, Jaroslav, Vítek, Libor

“…Mild constitutive hyperbilirubinemia is associated with a reduced risk of cardiovascular diseases, diabetes, and cancer. Since these pathologies are associated…”
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Antiproliferative effects of carbon monoxide on pancreatic cancer by Vítek, Libor, Gbelcová, Helena, Muchová, Lucie, Váňová, Kateřina, Zelenka, Jaroslav, Koníčková, Renata, Šuk, Jakub, Zadinova, Marie, Knejzlík, Zdeněk, Ahmad, Shakil, Fujisawa, Takeshi, Ahmed, Asif, Ruml, Tomáš

“…Abstract Background Carbon monoxide, the gaseous product of heme oxygenase, is a signalling molecule with a broad spectrum of biological activities. The aim of…”
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Thermoresponsive polymeric radionuclide delivery system—An injectable brachytherapy by Hruby, Martin, Pouckova, Pavla, Zadinova, Marie, Kucka, Jan, Lebeda, Ondrej

“…Brachytherapy is of increasing popularity in clinical oncology for the local therapy of solid tumors due to high radiation doses delivered to malignant tissue…”
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The impact of intestinal microflora on serum bilirubin levels by Vítek, Libor, Zelenka, Jaroslav, Zadinová, Marie, Malina, Jiří

“…Intestinal microflora plays an important role in the pathogenesis of neonatal jaundice by inhibiting enterosystemic circulation of bilirubin. The present study…”
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The Effect of Zinc Salts on Serum Bilirubin Levels in Hyperbilirubinemic Rats by Vítek, Libor, Muchová, Lucie, Zelenka, Jaroslav, Zadinová, Marie, Malina, Jiří

“…ABSTRACT Objectives: Intestinal metabolism of bilirubin is implicated in the pathogenesis of neonatal jaundice and Crigler‐Najjar syndrome. In the present…”
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Establishment, growth and in vivo differentiation of a new clonal human cell line, EM-G3, derived from breast cancer progenitors by BROZOVA, Marketa, KLEIBL, Zdenek, KRASNA, Luboslava, MATOUSKOVA, Eva, NETIKOVA, Irena, SEVCIK, Jan, SCHOLZOVA, Eva, BREZINOVA, Jana, CHALOUPKOVA, Alena, VESELY, Pavel, DUNDR, Pavel, ZADINOVA, Marie

“…A new clonal cell line, EM-G3, was derived from a primary lesion of human infiltrating ductal breast carcinoma. The line consisted of cuboidal cells with…”
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Optimum modality for photodynamic therapy of tumors: gels containing liposomes with hydrophobic photosensitizers by Nekvasil, Miloš, Zadinová, Marie, Tahotná, Ludmila, Žáčková, Markéta, Poučková, Pavla, Ježek, Petr

“…Photodynamic therapy (PDT) has entered an era of clinical acceptance; however, for its wider use, including drug formulations for topical applications, it must…”
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Poly(2-ethyl-2-oxazoline) conjugates with doxorubicin for cancer therapy: In vitro and in vivo evaluation and direct comparison to poly[N-(2-hydroxypropyl)methacrylamide] analogues by Sedlacek, Ondrej, Monnery, Bryn D., Mattova, Jana, Kucka, Jan, Panek, Jiri, Janouskova, Olga, Hocherl, Anita, Verbraeken, Bart, Vergaelen, Maarten, Zadinova, Marie, Hoogenboom, Richard, Hruby, Martin

“…We designed and synthesized a new delivery system for the anticancer drug doxorubicin based on a biocompatible hydrophilic poly(2-ethyl-2-oxazoline) (PEtOx)…”
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Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumor activity of RNase A by MATOUSEK, Josef, POUCKOVA, Pavla, HLOUSKOVA, Daniela, ZADINOVA, Marie, SOUCEK, Josef, SKVOR, Jiri

“…Subcutaneous application of bovine RNase A conjugated to HYase (bovine hyaluronidase), polyethylene glycol (PEG) and HYase+PEG resulted in a marked reduction…”
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Experimental photodynamic therapy with MESO‐tetrakisphenylporphyrin (TPP) in liposomes leads to disintegration of human amelanotic melanoma implanted to nude mice by Ježek, Petr, Nekvasil, Milos, Škobisová, Eva, Urbánková, Eva, Jirsa, Milan, Zadinová, Marie, Poučková, Pavla, Klepáček, Ivo

“…Liposomal meso‐tetrakis‐phenylporphyrin (TPP) was tested for photodynamic therapy (PDT) of human amelanotic melanomas implanted in nude mice. After…”
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The Effect of Zinc Salts on Serum Bilirubin Levels in Hyperbilirubinemic Rats by V??tek, Libor, Muchov??, Lucie, Zelenka, Jaroslav, Zadinov??, Marie, Malina, Ji????

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Expression of proteinase-activated receptor 2 during taurocholate-induced acute pancreatic lesion development in Wistar rats by Olejár, T, Matej, R, Zadinová, M, Poucková, P

“…Proteinase-activated receptor 2 (PAR-2) is a G-protein coupled transmembrane receptor activated by trypsin by site-specific cleavage. Its presence on…”
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Radiation-induced production of PAR-1 and TGF-beta 1 mRNA in lung of C57Bl6 and C3H murine strains and influence of pharmacoprophylaxis by ACE inhibitors by Matěj, Radoslav, Housa, Daniel, Pouc˘ková, Pavla, Zadinová, Marie, Olejár, Tomáš

“…Transforming growth factor beta 1 (TGF- β1) plays an important role in the development of radiation- and drug-induced organ diseases. Proteinases-activated…”
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Dual role of host Par2 in a murine model of spontaneous metastatic B16 melanoma by Olejar, Tomas, Vetvicka, David, Zadinova, Marie, Pouckova, Pavla, Kukal, Jaromir, Jezek, Petr, Matej, Radoslav

“…We investigated differences of metastatic spread of normal proteinase-activated receptor-2 (Par2+/+) melanoma B16 in Par2-/- (knock-out) animals compared to…”
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Multistage-targeted pH-responsive polymer conjugate of Auger electron emitter: Optimized design and in vivo activity by Sedlacek, Ondrej, Kucka, Jan, Mattova, Jana, Parizek, Martin, Studenovsky, Martin, Zadinova, Marie, Pouckova, Pavla, Hruby, Martin

“…Auger electrons-emitting radioisotopes (such as iodine-125) are a potentially effective cancer treatment. They are extremely biologically effective, but only…”
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Evaluation of Topical Photodynamic Therapy of Mammary Carcinoma with an Experimental Gel Containing Liposomal Hydroxyl-aluminium Phthalocyanine by SUTORIS, Karol, VETVICKA, David, HORAK, Ladislav, BENES, Jiri, NEKVASIL, Milos, JEZEK, Petr, ZADINOVA, Marie, POUCKOVA, Pavla

“…Photodynamic therapy (PDT) is a clinically-accepted approach for the therapy of many types of cancer. This study focused on the treatment of mammarian…”
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