Search Results - "Zaczek, J. J"
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Circulating Tumor Cells in Early and Advanced Breast Cancer; Biology and Prognostic Value
Published in International journal of molecular sciences (29-02-2020)“…Breast cancer metastasis is the leading cause of cancer deaths in women and is difficult to combat due to the long periods in which disseminated cells retain a…”
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Mesenchymal phenotype of CTC-enriched blood fraction and lymph node metastasis formation potential
Published in PloS one (01-04-2014)“…Circulating tumor cells (CTCs) that present mesenchymal phenotypes can escape standard methods of isolation, thus limiting possibilities for their…”
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Mapping the polymorphic transformation gateway vibration in crystalline 1,2,4,5-tetrabromobenzene
Published in Chemical science (Cambridge) (07-02-2019)“…The thermosalient behavior of 1,2,4,5-tetrabromobenzene (TBB) is related to a temperature-induced polymorphic structural change. The mechanism behind the phase…”
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Transcriptomic landscape of blood platelets in healthy donors
Published in Scientific reports (03-08-2021)“…Blood platelet RNA-sequencing is increasingly used among the scientific community. Aberrant platelet transcriptome is common in cancer or cardiovascular…”
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Cytocompatibility of stabilized black phosphorus nanosheets tailored by directly conjugated polymeric micelles for human breast cancer therapy
Published in Scientific reports (29-04-2021)“…The novel procedure of few-layer black phosphorus (FLBP) stabilization and functionalisation was here proposed. The cationic polymer PLL and non-ionic PEG have…”
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imPlatelet classifier: image‐converted RNA biomarker profiles enable blood‐based cancer diagnostics
Published in Molecular oncology (01-10-2021)“…Liquid biopsies offer a minimally invasive sample collection, outperforming traditional biopsies employed for cancer evaluation. The widely used material is…”
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Reduced expression of innate immunity-related genes in lymph node metastases of luminal breast cancer patients
Published in Scientific reports (03-03-2021)“…Immune system plays a dual role in cancer by either targeting or supporting neoplastic cells at various stages of disease, including metastasis. Yet, the exact…”
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Chimeric virus-like particles presenting tumour-associated MUC1 epitope result in high titers of specific IgG antibodies in the presence of squalene oil-in-water adjuvant: towards safe cancer immunotherapy
Published in Journal of nanobiotechnology (27-03-2022)“…Immunotherapy is emerging as a powerful treatment approach for several types of cancers. Modulating the immune system to specifically target cancer cells while…”
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FGF7/FGFR2–JunB signalling counteracts the effect of progesterone in luminal breast cancer
Published in Molecular oncology (01-08-2022)“…We have recently demonstrated that fibroblast growth factor receptor 2 (FGFR2)‐mediated signalling alters progesterone receptor (PR) activity and response of…”
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Prognostic significance of ESR1 amplification and ESR1 PvuII, CYP2C192, UGT2B152 polymorphisms in breast cancer patients
Published in PloS one (08-08-2013)“…Amplification of the ESR1 gene, coding for estrogen receptor alpha, was shown to predict responsiveness to tamoxifen, however its prognostic impact in breast…”
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Expression of epithelial to mesenchymal transition-related markers in lymph node metastases as a surrogate for primary tumor metastatic potential in breast cancer
Published in Journal of translational medicine (19-11-2012)“…Breast cancers are phenotypically and genotypically heterogeneous tumors containing multiple cancer cell populations with various metastatic potential…”
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Diagnostic Accuracy of Liquid Biopsy in Endometrial Cancer
Published in Cancers (16-11-2021)“…Background: Liquid biopsy is a minimally invasive collection of a patient body fluid sample. In oncology, they offer several advantages compared to traditional…”
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Aggressive Phenotype of Cells Disseminated via Hematogenous and Lymphatic Route in Breast Cancer Patients
Published in Translational oncology (01-06-2018)“…Intratumoral heterogeneity of breast cancer remains a major challenge in successful treatment. Failure of cancer therapies can also be accredited to inability…”
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microRNA Expression Profile in Single Hormone Receptor-Positive Breast Cancers Is Mainly Dependent on HER2 Status—A Pilot Study
Published in Diagnostics (Basel) (20-08-2020)“…Estrogen (ER) and progesterone (PgR) receptors and HER2 are crucial in the assessment of breast cancer specimens due to their prognostic and predictive…”
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Composition, diversity, and height of tree regeneration, 3 years after soil scarification in a mixed-oak shelterwood
Published in Forest ecology and management (28-06-2002)“…This study reports the effects of soil scarification soon after dissemination of northern red oak ( Quercus rubra L.) acorns on species composition, density,…”
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Fire and Fertilization Effects on the Growth and Spread of Rhizome-Transplanted Giant Cane (Arundinaria gigantea)
Published in Restoration ecology (01-11-2010)“…In the United States, clonal bamboo stands dominated by giant cane (Arundinaria gigantea), historically described as “canebrakes,” have been largely degraded…”
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Epithelial-mesenchymal transition: a hallmark in metastasis formation linking circulating tumor cells and cancer stem cells
Published in Pathobiology (Basel) (01-01-2012)“…The occurrence of either regional or distant metastases is an indicator of poor prognosis for cancer patients. The mechanism of their formation has not yet…”
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Breast cancer circulating tumor cells with mesenchymal features—an unreachable target?
Published in Cellular and molecular life sciences : CMLS (01-02-2022)“…Circulating tumor cells (CTCs) mediate dissemination of solid tumors and can be an early sign of disease progression. Moreover, they show a great potential in…”
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Alpha-smooth muscle actin-positive cancer-associated fibroblasts secreting osteopontin promote growth of luminal breast cancer
Published in Cellular & molecular biology letters (11-06-2022)“…Cancer-associated fibroblasts (CAFs) have been shown to support tumor development in a variety of cancers. Different markers were applied to classify CAFs in…”
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