Search Results - "Zack, D."

Laser-cooled polyatomic molecules for improved electron electric dipole moment searches by Augenbraun, Benjamin L, Lasner, Zack D, Frenett, Alexander, Sawaoka, Hiromitsu, Miller, Calder, Steimle, Timothy C, Doyle, John M

“…Doppler and Sisyphus cooling of 174YbOH are achieved and studied. This polyatomic molecule has high sensitivity to physics beyond the Standard Model and…”
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Zeeman-Sisyphus Deceleration of Molecular Beams by Augenbraun, Benjamin L, Frenett, Alexander, Sawaoka, Hiromitsu, Hallas, Christian, Vilas, Nathaniel B, Nasir, Abdullah, Lasner, Zack D, Doyle, John M

“…We present a robust, continuous molecular decelerator that employs high magnetic fields and few optical pumping steps. CaOH molecules are slowed, accumulating…”
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Micronuclear collapse from oxidative damage by Di Bona, Melody, Chen, Yanyang, Agustinus, Albert S, Mazzagatti, Alice, Duran, Mercedes A, Deyell, Matthew, Bronder, Daniel, Hickling, James, Hong, Christy, Scipioni, Lorenzo, Tedeschi, Giulia, Martin, Sara, Li, Jun, Ruzgaitė, Aušrinė, Riaz, Nadeem, Shah, Parin, D'Souza, Edridge K, Brodtman, D Zack, Sidoli, Simone, Diplas, Bill, Jalan, Manisha, Lee, Nancy Y, Ordureau, Alban, Izar, Benjamin, Laughney, Ashley M, Powell, Simon, Gratton, Enrico, Santaguida, Stefano, Maciejowski, John, Ly, Peter, Jeitner, Thomas M, Bakhoum, Samuel F

“…Chromosome-containing micronuclei are a hallmark of aggressive cancers. Micronuclei frequently undergo irreversible collapse, exposing their enclosed chromatin…”
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Functionalizing aromatic compounds with optical cycling centres by Zhu, Guo-Zhu, Mitra, Debayan, Augenbraun, Benjamin L., Dickerson, Claire E., Frim, Michael J., Lao, Guanming, Lasner, Zack D., Alexandrova, Anastassia N., Campbell, Wesley C., Caram, Justin R., Doyle, John M., Hudson, Eric R.

“…Molecular design principles provide guidelines for augmenting a molecule with a smaller group of atoms to realize a desired property or function. We…”
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Cryo-EM structures of an insecticidal Bt toxin reveal its mechanism of action on the membrane by Byrne, Matthew J., Iadanza, Matthew G., Perez, Marcos Arribas, Maskell, Daniel P., George, Rachel M., Hesketh, Emma L., Beales, Paul A., Zack, Marc D., Berry, Colin, Thompson, Rebecca F.

“…Insect pests are a major cause of crop losses worldwide, with an estimated economic cost of $470 billion annually. Biotechnological tools have been introduced…”
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Pathway toward Optical Cycling and Laser Cooling of Functionalized Arenes by Mitra, Debayan, Lasner, Zack D., Zhu, Guo-Zhu, Dickerson, Claire E., Augenbraun, Benjamin L., Bailey, Austin D., Alexandrova, Anastassia N., Campbell, Wesley C., Caram, Justin R., Hudson, Eric R., Doyle, John M.

“…Rapid and repeated photon cycling has enabled precision metrology and the development of quantum information systems using atoms and simple molecules…”
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Autozygome-guided exome sequencing in retinal dystrophy patients reveals pathogenetic mutations and novel candidate disease genes by Abu-Safieh, Leen, Alrashed, May, Anazi, Shamsa, Alkuraya, Hisham, Khan, Arif O, Al-Owain, Mohammed, Al-Zahrani, Jawahir, Al-Abdi, Lama, Hashem, Mais, Al-Tarimi, Salwa, Sebai, Mohammed-Adeeb, Shamia, Ahmed, Ray-Zack, Mohamed D, Nassan, Malik, Al-Hassnan, Zuhair N, Rahbeeni, Zuhair, Waheeb, Saad, Alkharashi, Abdullah, Abboud, Emad, Al-Hazzaa, Selwa A F, Alkuraya, Fowzan S

“…Retinal dystrophy (RD) is a heterogeneous group of hereditary diseases caused by loss of photoreceptor function and contributes significantly to the etiology…”
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Assessment and mitigation of aerosol airborne SARS-CoV-2 transmission in laboratory and office environments by Augenbraun, Benjamin L, Lasner, Zack D, Mitra, Debayan, Prabhu, Sridhar, Raval, Shivam, Sawaoka, Hiromitsu, Doyle, John M

“…Bioaerosols are known to be an important transmission pathway for SARS-CoV-2. We report a framework for estimating the risk of transmitting SARS-CoV-2 via…”
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Alternative splicing and retinal degeneration by Liu, M M, Zack, D J

“…Alternative splicing is highly regulated in tissue‐specific and development‐specific patterns, and it has been estimated that 15% of disease‐causing point…”
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Mapping variant effects on anti-tumor hallmarks of primary human T cells with base-editing screens by Walsh, Zachary H, Shah, Parin, Kothapalli, Neeharika, Shah, Shivem B, Nikolenyi, Gergo, Brodtman, D Zack, Leuzzi, Giuseppe, Rogava, Meri, Mu, Michael, Ho, Patricia, Abuzaid, Sinan, Vasan, Neil, AlQuraishi, Mohammed, Milner, Joshua D, Ciccia, Alberto, Melms, Johannes C, Izar, Benjamin

“…Single-nucleotide variants (SNVs) in key T cell genes can drive clinical pathologies and could be repurposed to improve cellular cancer immunotherapies. Here,…”
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Single-cell profiling of sarcomas from archival tissue reveals programs associated with resistance to immune checkpoint blockade by Luthria, Karan, Shah, Parin, Caldwell, Blake, Melms, Johannes C, Abuzaid, Sinan, Jakubikova, Viktoria, Brodtman, D Zack, Bose, Sminu, Amin, Amit Dipak, Ho, Patricia, Biermann, Jana, Tagore, Somnath, Ingham, Matthew, Schwartz, Gary K, Izar, Benjamin

“…Sarcoma encompasses a diverse group of cancers that are typically resistant to current therapies, including immune checkpoint blockade (ICB), and underlying…”
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Infections in postmenopausal women with osteoporosis treated with denosumab or placebo: coincidence or causal association? by Watts, N. B., Roux, C., Modlin, J. F., Brown, J. P., Daniels, A., Jackson, S., Smith, S., Zack, D. J., Zhou, L., Grauer, A., Ferrari, S.

“…Summary Serious adverse events of infections that occurred in subjects receiving denosumab or placebo in the Fracture Reduction Evaluation of Denosumab in…”
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Relationship between Visitors’ Sense of Place, Recreation Behavior, and Acceptability of Resource Allocation Strategies at a Reservoir Facing a Water Crisis by Darby, Zack D, Poudyal, Neelam Chandra, Frakes, Adam, Joshi, Omkar

“…Municipal drawdowns at public reservoirs can negatively impact recreational uses on site. Therefore, sustaining recreation requires understanding how users…”
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Thioredoxin rod-derived cone viability factor protects against photooxidative retinal damage by Elachouri, G., Lee-Rivera, I., Clérin, E., Argentini, M., Fridlich, R., Blond, F., Ferracane, V., Yang, Y., Raffelsberger, W., Wan, Jun, Bennett, J., Sahel, J.-A., Zack, D.J., Léveillard, T.

“…Rod-derived cone viability factor (RdCVF) is a trophic factor of the thioredoxins family that promotes the survival of cone photoreceptors. It is encoded by…”
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Transcriptional profiling and pathway analysis of CSF-1 and IL-34 effects on human monocyte differentiation by Barve, Ruteja A., Zack, Marc D., Weiss, David, Song, Ruo-Hua, Beidler, David, Head, Richard D.

“…•We compared transcriptional profiles of CSF-1 and IL-34 treated human monocytes.•Majority of changes were similar and characteristic of a macrophage…”
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Hospital length of stay following radical cystectomy for muscle-invasive bladder cancer: Development and validation of a population-based prediction model by Ray-Zack, Mohamed D., Shan, Yong, Mehta, Hemalkumar B., Yu, Xiaoying, Kamat, Ashish M., Williams, Stephen B.

“…Length of hospital stay for patients following radical cystectomy is an important determinant for improved quality of care. We sought to develop and validate a…”
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Angiopoietin 1 inhibits ocular neovascularization and breakdown of the blood-retinal barrier by NAMBU, H, NAMBU, R, OSHIMA, Y, HACKETT, S. F, OKOYE, G, WIEGAND, S, YANCOPOULOS, G, ZACK, D. J, CAMPOCHIARO, P. A

“…Several retinal and choroidal diseases are potentially treatable by intraocular delivery of genes whose products may counter or neutralize abnormal gene…”
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Obstructed Axonal Transport of BDNF and Its Receptor TrkB in Experimental Glaucoma by Pease, Mary Ellen, McKinnon, Stuart J, Quigley, Harry A, Kerrigan-Baumrind, Lisa A, Zack, Donald J

“…In both animal model system and in human glaucoma, retinal ganglion cells (RGCs) die by apoptosis. To understand how RGC apoptosis is initiated in these…”
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No Difference in Mechanical Ventilation Free Hours in Critically Ill Patients who Received Intravenous, Oral, or Enteral Phosphate Replacement by Lemon, Stephen J., PharmD, BCPS, Zack, Stephanie D., PharmD, BCPS, Voils, Stacy A., PharmD, M.Sc., BCPS, FCCM

“…Abstract Purpose To determine the impact on duration of mechanical ventilation (MV) and the need for reintubation after changing from intravenous (IV) to oral…”
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Retrograde Axonal Transport of BDNF in Retinal Ganglion Cells Is Blocked by Acute IOP Elevation in Rats by Quigley, Harry A, McKinnon, Stuart J, Zack, Donald J, Pease, Mary Ellen, Kerrigan-Baumrind, Lisa A, Kerrigan, Danielle F, Mitchell, Rebecca S

“…To determine whether acute experimental glaucoma in rats obstructs retrograde transport of brain-derived neurotrophic factor (BDNF) to retinal ganglion cells…”
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