Search Results - "Zacharias, David"
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Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice
Published in Atherosclerosis (01-11-2011)“…Abstract Objective Humanin (HN) is a cytoprotective peptide derived from endogenous mitochondria, expressed in the endothelial layer of human vessels, but its…”
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Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells
Published in Science (American Association for the Advancement of Science) (03-05-2002)“…Many proteins associated with the plasma membrane are known to partition into submicroscopic sphingolipid- and cholesterol-rich domains called lipid rafts, but…”
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3
A Monomeric Red Fluorescent Protein
Published in Proceedings of the National Academy of Sciences - PNAS (11-06-2002)“…All coelenterate fluorescent proteins cloned to date display some form of quaternary structure, including the weak tendency of Aequorea green fluorescent…”
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Humanin, a Cytoprotective Peptide, Is Expressed in Carotid Artherosclerotic Plaques in Humans
Published in PloS one (06-02-2012)“…Objective The mechanism of atherosclerotic plaque progression leading to instability, rupture, and ischemic manifestation involves oxidative stress and…”
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5
Role of Alternative Splicing in Generating Isoform Diversity Among Plasma Membrane Calcium Pumps
Published in Physiological reviews (01-01-2001)“…Department of Biochemistry and Molecular Biology, Mayo Graduate School, Mayo Clinic/Foundation, Rochester, Minnesota; and Howard Hughes Medical Institute, Cell…”
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Biochemistry, Mutagenesis, and Oligomerization of DsRed, a Red Fluorescent Protein from Coral
Published in Proceedings of the National Academy of Sciences - PNAS (24-10-2000)“…DsRed is a recently cloned 28-kDa fluorescent protein responsible for the red coloration around the oral disk of a coral of the Discosoma genus. DsRed has…”
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The Science and Ethics of Induced Pluripotency: What Will Become of Embryonic Stem Cells?
Published in Mayo Clinic proceedings (01-07-2011)“…For over a decade, the field of stem cell research has advanced tremendously and gained new attention in light of novel insights and emerging developments for…”
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Relation between half‐cell and fuel cell activity and stability of FeNC catalysts for the oxygen reduction reaction
Published in SusMat (Online) (01-10-2022)“…FeNC catalysts are promising substitutes of platinum‐type catalysts for the oxygen reduction reaction (ORR). While previous research disclosed that high…”
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Identification of CKAP4/p63 as a Major Substrate of the Palmitoyl Acyltransferase DHHC2, a Putative Tumor Suppressor, Using a Novel Proteomics Method
Published in Molecular & cellular proteomics (01-07-2008)“…Protein palmitoylation is the post-translational addition of the 16-carbon fatty acid palmitate to specific cysteine residues by a labile thioester linkage…”
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Palmitoylation of cytoskeleton associated protein 4 by DHHC2 regulates antiproliferative factor-mediated signaling
Published in Molecular biology of the cell (01-03-2009)“…Previously, we identified cytoskeleton-associated protein 4 (CKAP4) as a major substrate of the palmitoyl acyltransferase, DHHC2, using a novel proteomic…”
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11
Genetically targeted chromophore-assisted light inactivation
Published in Nature biotechnology (01-12-2003)“…Studies of protein function would be facilitated by a general method to inactivate selected proteins in living cells noninvasively with high spatial and…”
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Survey of the Clinical Assessment and Utility of Near-Infrared Cerebral Oximetry in Cardiac Surgery
Published in Journal of cardiothoracic and vascular anesthesia (01-04-2014)“…Objectives Near-infrared cerebral oximetry increasingly is used for monitoring during cardiac surgery. Nonetheless, the scientific basis for incorporating this…”
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13
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
Published in Science (American Association for the Advancement of Science) (30-06-2000)“…Heterozygous mutations encoding abnormal forms of the death receptor Fas dominantly interfere with Fas-induced lymphocyte apoptosis in human autoimmune…”
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14
Palmitoyl acyltransferases, their substrates, and novel assays to connect them (Review)
Published in Molecular membrane biology (01-01-2009)“…Thio-palmitoylation is the post-translational addition of the 16-carbon fatty acid, palmitate, to the thiol side chain of cysteine residues by a labile…”
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15
A Meta-Analysis of Human Acellular Dermis and Submuscular Tissue Expander Breast Reconstruction
Published in Plastic and reconstructive surgery (1963) (01-12-2012)Get full text
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Co-testing for detection of high-grade cervical intraepithelial neoplasia and cancer compared with cytology alone: a meta-analysis of randomized controlled trials
Published in Journal of public health (Oxford, England) (01-03-2014)“…Background Human papillomavirus (HPV) DNA testing combined with cytology has been recommended as a primary cervical cancer screening strategy. Methods…”
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Antiproliferative Factor-Induced Changes in Phosphorylation and Palmitoylation of Cytoskeleton-Associated Protein-4 Regulate Its Nuclear Translocation and DNA Binding
Published in International Journal of Cell Biology (2012)“…Cytoskeleton-associated protein 4 (CKAP4) is a reversibly palmitoylated and phosphorylated transmembrane protein that functions as a high-affinity receptor for…”
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18
Circular Permutation and Receptor Insertion within Green Fluorescent Proteins
Published in Proceedings of the National Academy of Sciences - PNAS (28-09-1999)“…Many areas of biology and biotechnology have been revolutionized by the ability to label proteins genetically by fusion to the Aequorea green fluorescent…”
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19
Recent advances in technology for measuring and manipulating cell signals
Published in Current Opinion in Neurobiology (01-06-2000)“…Signal transduction research has made some glowing progress in the past 12 months. Recent advances in fluorescent proteins, small molecule fluorophores and…”
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The palmitoylation state of PMP22 modulates epithelial cell morphology and migration
Published in ASN neuro (03-12-2012)“…PMP22 (peripheral myelin protein 22), also known as GAS 3 (growth-arrest-specific protein 3), is a disease-linked tetraspan glycoprotein of peripheral nerve…”
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