Search Results - "Zabrocki, Janusz"

A Global Review on Short Peptides: Frontiers and Perspectives by Apostolopoulos, Vasso, Bojarska, Joanna, Chai, Tsun-Thai, Elnagdy, Sherif, Kaczmarek, Krzysztof, Matsoukas, John, New, Roger, Parang, Keykavous, Lopez, Octavio Paredes, Parhiz, Hamideh, Perera, Conrad O, Pickholz, Monica, Remko, Milan, Saviano, Michele, Skwarczynski, Mariusz, Tang, Yefeng, Wolf, Wojciech M, Yoshiya, Taku, Zabrocki, Janusz, Zielenkiewicz, Piotr, AlKhazindar, Maha, Barriga, Vanessa, Kelaidonis, Konstantinos, Sarasia, Elham Mousavinezhad, Toth, Istvan

“…Peptides are fragments of proteins that carry out biological functions. They act as signaling entities via all domains of life and interfere with…”
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A Supramolecular Approach to Structure-Based Design with A Focus on Synthons Hierarchy in Ornithine-Derived Ligands: Review, Synthesis, Experimental and in Silico Studies by Bojarska, Joanna, Remko, Milan, Breza, Martin, Madura, Izabela D, Kaczmarek, Krzysztof, Zabrocki, Janusz, Wolf, Wojciech M

“…The success of innovative drugs depends on an interdisciplinary and holistic approach to their design and development. The supramolecular architecture of…”
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Antiviral Activity of a Cyclic Pro-Pro-β3-HoPhe-Phe Tetrapeptide against HSV-1 and HAdV-5 by Zaczyńska, Ewa, Kaczmarek, Krzysztof, Zabrocki, Janusz, Artym, Jolanta, Zimecki, Michał

“…The core of Cyclolinopeptide A (CLA, cyclo(LIILVPPFF)), responsible for its high immunosuppressive activity, contains a Pro-Pro-Phe-Phe sequence. A newly…”
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Solid-Phase Synthesis of an Insect Pyrokinin Analog Incorporating an Imidazoline Ring as Isosteric Replacement of a trans Peptide Bond by Kaczmarek, Krzysztof, Pacholczyk-Sienicka, Barbara, Albrecht, Łukasz, Zabrocki, Janusz, Nachman, Ronald J.

“…A facile solid-phase synthetic method for incorporating the imidazoline ring motif, a surrogate for a trans peptide bond, into bioactive peptides is reported…”
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Bee-safe peptidomimetic acaricides achieved by comparative genomics by Jindal, Vikas, Li, Daqi, Rault, Leslie C., Fatehi, Soheila, Singh, Rupinder, Mating, Moritz, Zou, Ye, Ng, Ho-Leung, Kaczmarek, Krzysztof, Zabrocki, Janusz, Gui, Shunhua, Smagghe, Guy, Anderson, Troy D., Nachman, Ronald J., Park, Yoonseong

“…The devastating Varroa mite ( Varroa destructor Anderson and Trueman) is an obligatory ectoparasite of the honey bee, contributing to significant colony losses…”
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Disruption of insect diapause using agonists and an antagonist of diapause hormone by Zhang, Qirui, Nachman, Ronald J, Kaczmarek, Krzysztof, Zabrocki, Janusz, Denlinger, David L

“…The dormant state known as diapause is widely exploited by insects to circumvent winter and other adverse seasons. For an insect to survive, feed, and…”
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Function of the natalisin receptor in mating of the oriental fruit fly, Bactrocera dorsalis (Hendel) and testing of peptidomimetics by Gui, Shun-Hua, Pei, Yu-Xia, Xu, Li, Wang, Wei-Ping, Jiang, Hong-Bo, Nachman, Ronald J, Kaczmarek, Krzysztof, Zabrocki, Janusz, Wang, Jin-Jun

“…Natalisins (NTLs) are conservative neuropeptides, which are only found in arthropods and are documented to regulate reproductive behaviors in insects. In our…”
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Biostable and PEG polymer-conjugated insect pyrokinin analogs demonstrate antifeedant activity and induce high mortality in the pea aphid Acyrthosiphon pisum (Hemiptera: Aphidae) by Nachman, Ronald J., Hamshou, Mohamad, Kaczmarek, Krzysztof, Zabrocki, Janusz, Smagghe, Guy

“…► Biostable insect pyrokinin analogs with Oic show potent oral antifeedant and aphicidal activity. ► A PEG-polymer conjugated pyrokinin analog shows potent…”
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Anti-Inflammatory Activity of a Cyclic Tetrapeptide in Mouse and Human Experimental Models by Zimecki, Michał, Artym, Jolanta, Kałas, Wojciech, Strządała, Leon, Kaleta-Kuratewicz, Katarzyna, Kuryszko, Jan, Kaszuba, Andrzej, Kaczmarek, Krzysztof, Zabrocki, Janusz

“…A cyclic tetrapeptide Pro-Pro-Pheβ3ho-Phe (4B8M) was tested for immunosuppressive activity and potential therapeutic utility in several in vitro and in vivo…”
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Activity of native tick kinins and peptidomimetics on the cognate target G protein‐coupled receptor from the cattle fever tick, Rhipicephalus microplus (Acari: Ixodidae) by Xiong, Caixing, Kaczmarek, Krzysztof, Zabrocki, Janusz, Nachman, Ronald J, Pietrantonio, Patricia V

“…BACKGROUND Kinins are multifunctional neuropeptides that regulate key insect physiological processes such as diuresis, feeding, and ecdysis. However, the…”
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New synthons in supramolecular chemistry of short biologically active peptides by Bojarska, Joanna, Wolf, Wojciech, Zabrocki, Janusz, Kaczmarek, Krzysztof, Remko, Milan

“…Abstract only…”
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Supramolecular synthon polymorphism in modified amino acids. Structural, conformational and energy landscapes of N-benzoyl-2′-hydroxy-3-methylisovaline by Bojarska, Joanna, Remko, Milan, Madura, Izabela D., Wojciechowski, Jakub M., Olczak, Andrzej, Kaczmarek, Krzysztof, Zabrocki, Janusz, Wolf, Wojciech M.

“…The title compound, N-benzoyl-2′-hydroxy-3-methylisovaline, representing synthon polymorphism, can be interesting inter alia from the point of view of modern…”
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Evaluation of Aib and PEG-polymer insect kinin analogs on mosquito and tick GPCRs identifies potent new pest management tools with potentially enhanced biostability and bioavailability by Xiong, Caixing, Kaczmarek, Krzysztof, Zabrocki, Janusz, Pietrantonio, Patricia V., Nachman, Ronald J.

“…•Novel biostable and bioavailable insect kinin (IK) analogs were designed.•Novel IK analogs were potent on mosquito and tick kinin receptors.•Potency and…”
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Functional characterization of five different PRXamide receptors of the red flour beetle Tribolium castaneum with peptidomimetics and identification of agonists and antagonists by Jiang, Hongbo, Wei, Zhaojun, Nachman, Ronald J., Kaczmarek, Krzysztof, Zabrocki, Janusz, Park, Yoonseong

“…•70 different analogs of PRXamide peptide were tested on five different receptors.•A ligand acting on multiple receptors is common.•Agonistic or antagonistic…”
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Antiviral Activity of a Cyclic Pro-Pro- β 3 -HoPhe-Phe Tetrapeptide against HSV-1 and HAdV-5 by Zaczyńska, Ewa, Kaczmarek, Krzysztof, Zabrocki, Janusz, Artym, Jolanta, Zimecki, Michał

“…The core of Cyclolinopeptide A (CLA, cyclo(LIILVPPFF)), responsible for its high immunosuppressive activity, contains a Pro-Pro-Phe-Phe sequence. A newly…”
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Ligand selectivity in tachykinin and natalisin neuropeptidergic systems of the honey bee parasitic mite Varroa destructor by Jiang, Hongbo, Kim, Donghun, Dobesh, Sharon, Evans, Jay D., Nachman, Ronald J., Kaczmarek, Krzysztof, Zabrocki, Janusz, Park, Yoonseong

“…The varroa mite, Varroa destructor , is a devastating ectoparasite of the honey bees Apis mellifera and A. cerana . Control of these mites in beehives is a…”
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Synthesis, experimental and in silico studies of N‐fluorenylmethoxycarbonyl‐O‐tert‐butyl‐N‐methyltyrosine, coupled with CSD data: a survey of interactions in the crystal structures of Fmoc–amino acids by Bojarska, Joanna, Remko, Milan, Madura, Izabela D., Kaczmarek, Krzysztof, Zabrocki, Janusz, Wolf, Wojciech M.

“…Recently, fluorenylmethoxycarbonyl (Fmoc) amino acids (e.g. Fmoc–tyrosine or Fmoc–phenylalanine) have attracted growing interest in biomedical research and…”
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Conformational mimicry. 1. 1,5-Disubstituted tetrazole ring as a surrogate for the cis amide bond by Zabrocki, Janusz, Smith, G. David, Dunbar, James B, Iijima, Hiroshi, Marshall, Garland R

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Conformational analysis of a cyclic AKH neuropeptide analog that elicits selective activity on locust versus honeybee receptor by Abdulganiyyu, Ibrahim A., Kaczmarek, Krzysztof, Zabrocki, Janusz, Nachman, Ronald J., Marchal, Elisabeth, Schellens, Sam, Verlinden, Heleen, Broeck, Jozef Vanden, Marco, Heather, Jackson, Graham E.

“…Neuropeptides belonging to the adipokinetic hormone (AKH) family elicit metabolic effects as their main function in insects, by mobilizing trehalose,…”
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4-Methylpseudoproline analogues of cyclolinopeptide A: Synthesis, structural analysis and evaluation of their suppressive effects in selected immunological assays by Katarzyńska, Joanna, Artym, Jolanta, Kochanowska, Iwona, Jędrzejczak, Karol, Zimecki, Michał, Lisowski, Marek, Wieczorek, Robert, Piotrowski, Łukasz, Marcinek, Andrzej, Zabrocki, Janusz, Jankowski, Stefan

“…•Two analogues of cyclolinopeptide A modified with (R)-4-methylpseudoproline exhibit high antiproliferative activity.•The replacement of Pro3 in CLA by…”
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