Search Results - "Zabluda, Vladimir N."
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The role of SAXS and molecular simulations in 3D structure elucidation of a DNA aptamer against lung cancer
Published in Molecular therapy. Nucleic acids (03-09-2021)“…Aptamers are short, single-stranded DNA or RNA oligonucleotide molecules that function as synthetic analogs of antibodies and bind to a target molecule with…”
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11C-radiolabeled aptamer for imaging of tumors and metastases using positron emission tomography- computed tomography
Published in Molecular therapy. Nucleic acids (03-12-2021)“…Identification of primary tumors and metastasis sites is an essential step in cancer diagnostics and the following treatment. Positron emission…”
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Structure‐ and Interaction‐Based Design of Anti‐SARS‐CoV‐2 Aptamers
Published in Chemistry : a European journal (24-02-2022)“…Aptamer selection against novel infections is a complicated and time‐consuming approach. Synergy can be achieved by using computational methods together with…”
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Four steps for revealing and adjusting the 3D structure of aptamers in solution by small-angle X-ray scattering and computer simulation
Published in Analytical and bioanalytical chemistry (01-10-2019)“…Nucleic acid (NA) aptamers bind to their targets with high affinity and selectivity. The three-dimensional (3D) structures of aptamers play a major role in…”
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Aptamer-Conjugated Superparamagnetic Ferroarabinogalactan Nanoparticles for Targeted Magnetodynamic Therapy of Cancer
Published in Cancers (15-01-2020)“…Nanotechnologies involving physical methods of tumor destruction using functional oligonucleotides are promising for targeted cancer therapy. Our study…”
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Cover Feature: Structure‐ and Interaction‐Based Design of Anti‐SARS‐CoV‐2 Aptamers (Chem. Eur. J. 12/2022)
Published in Chemistry : a European journal (24-02-2022)“…Digital drug design reveals DNA aptamers binding SARS‐CoV‐2: A hybrid in silico et vitro approach, structure and interaction‐based drug design, has been…”
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Structure- and Interaction-Based Design of Anti-SARS-CoV-2 Aptamers
Published in Chemistry : a European journal (09-02-2022)“…Aptamer selection against novel infections is a complicated and time-consuming approach. Synergy can be achieved by using computational methods together with…”
Get full text
Journal Article