Search Results - "Zabik, J E"

Interactive dopaminergic and noradrenergic systems in the regulation of thirst in the rat by Zabik, J E, Sprague, J E, Odio, M

“…Twenty-three hours of fluid deprivation led to elevated plasma levels of corticosterone and free fatty acids, as well as increased whole brain dopamine levels,…”
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Central and peripheral components of the inhibitory actions of 5-HTP on ethanol consumption in the rat by Zabik, J E, Sprague, J E, Binkerd, K

“…When administered under a backward conditioning paradigm, 5-HTP administration resulted in a decrease in ethanol intake followed by a persistently decreased…”
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Effects of anorexigenic agents on deprivation-induced fluid consumption by rats by Zabik, J E, Johnson, W, Maickel, R P

“…The effects of single doses of anorexigenic agents were determined on deprivation-induced fluid consumption by rats. The most potent compound was…”
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Effects of toluene inhalation on brain biogenic amines in the rat by Rea, T M, Nash, J F, Zabik, J E, Born, G S, Kessler, W V

“…The effects of toluene exposure on the biogenic amine concentrations in the central nervous system were investigated in the rat. Toluene was administered via…”
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Effects of benzodiazepines on taste aversions in a two-bottle choice paradigm by Roache, J D, Zabik, J E

“…Diazepam (DZ) and chlordiazepoxide (CDP) were tested for their ability to antagonize LiCl-established conditioned taste aversions (CTAs) to saccharin in a…”
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Substituent branching in phenethylamine-type hallucinogens: a comparison of 1-[2,5-dimethoxy-4-(2-butyl)phenyl]-2-aminopropane and 1-[2,5-dimethoxy-4-(2-methylpropyl)phenyl]-2-aminopropane by Oberlender, Robert A, Kothari, Paresh J, Nichols, David E, Zabik, Joseph E

“…Two novel hallucinogen analogues related to 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM, STP) were synthesized and evaluated in the two-lever drug…”
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Unreliability of the rat stomach fundus as a predictor of hallucinogenic activity in substituted phenethylamines by Nichols, D E, Schooler, D, Yeung, M C, Oberlender, R A, Zabik, J E

“…A series of three isomeric 2,4,5-substituted monoethoxy dimethoxy phenylisopropylamines were compared for their contractile effect in the rat fundus as…”
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Differential activity of enantiomers of amphetamine in rats by Maickel, R P, Light, K E, Zabik, J E

“…Administration of single doses of d-amphetamine (0.5-4.0 mg/kg i.p.) to adult, male rats produced the expected dose-related increases in spontaneous motor…”
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Synthesis and evaluation of substituted 2-phenylcyclobutylamines as analogs of hallucinogenic phenethylamines: lack of LSD-like biological activity by Nichols, David E, Jadhav, Kiran P, Oberlender, Robert A, Zabik, Joseph E, Bossart, Josef F, Hamada, Akihiko, Miller, Duane D

“…cis- and trans-2-(2,4,5-trimethoxyphenyl)cyclobutylamine and trans-2-(2,5-dimethoxy-4-methylphenyl)cyclobutylamine were synthesized as conformationally…”
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Interactions of tricyclic antidepressant drugs with deprivation-induced fluid consumption by rats by Zabik, J E, Levine, R M, Spaulding, J H, Maickel, R P

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Use of serotonin-active drugs in alcohol preference studies by Zabik, J E

“…Interest in finding a cure for alcoholism has sparked enthusiastic research into drugs that might accomplish this goal. Since decreases in brain serotonin had…”
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Effects of resination on actions of anorexigenic agents by Zabik, J E, Webb, R W, Maickel, R P

“…The salt and resinated forms of three anorexigenic agents, d-amphetamine, d,1-amphetamine, and phentermine were examined in rats using two test systems…”
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The effects of DL-5-hydroxytryptophan on ethanol consumption by rats by Zabik, J E, Liao, S S, Jeffreys, M, Maickel, R P

“…Rats were offered access to either distilled water or a 12% v/v solution of ethanol as their only fluid during a one hour period daily. After daily fluid…”
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Behavioral effects of psychotherapeutic agents in rats chronically dosed with alpha-acetylmethadol by Maickel, R P, Lambert, C S, Braude, M C, Zabik, J E

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Method for quantitative operant response measurement during inhalation exposure by Rea, T M, Zabik, J E, Kessler, W V, Born, G S

“…A method for pharmacologic and toxicologic investigation of operant responses during inhalation exposure has been developed. The method was tested with rats…”
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5-hydroxytryptophan-induced conditioned taste aversion to ethanol in the rat by Zabik, J E, Roache, J D

“…This experiment was conducted to determine the efficacy of 5-HTP in producing conditioned taste aversions (CTAs) to ethanol in rats restricted to a one-hour…”
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Tetrahydro-beta-carbolines in alcoholic beverages: quantitation, neurochemical and ethanol drinking effects by Bosin, T R, Krogh, S E, Zabik, J E

“…Two THBC compounds, 1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid and 1-methyl-1,2,3,4-tetrahydro-beta-carboxylic acid, have been quantitated in beers…”
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Stress, endogenous opioids and salt intake by Kuta, C C, Bryant, H U, Zabik, J E, Yim, G K

“…The effect of stress on NaCl intake was examined in mice given a choice of water and 1.5% NaCl to drink. Immobilization of mice for 15-min and 24-h food…”
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A simple animal test system to predict the likelihood of a drug causing human physical dependence by Maickel, R P, Zabik, J E

“…The test system utilizes adult, male, Sprague-Dawley rats to consume their entire daily water intake in a single 60 minute session. The results of…”
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The pharmacology of anorexigenesis by Maickel, R P, Zabik, J E

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