Search Results - "ZWANG, Y"

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  1. 1

    EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism by Pines, G, Huang, P H, Zwang, Y, White, F M, Yarden, Y

    Published in Oncogene (28-10-2010)
    “…Tumor cells often subvert normal regulatory mechanisms of signal transduction. This study shows this principle by studying yet uncharacterized mutants of the…”
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    Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling by SHTIEGMAN, K, KOCHUPURAKKAL, B. S, BENJAMIN, S, CORSO, S, GAN, J, YOSEF, R. B, GIORDANO, S, YARDEN, Y, ZWANG, Y, PINES, G, STARR, A, VEXLER, A, CITRI, A, KATZ, M, LAVI, S, BEN-BASAT, Y

    Published in Oncogene (25-10-2007)
    “…Several distinct mutations within the kinase domain of the epidermal growth factor receptor (EGFR) are associated with non-small cell lung cancer, but…”
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    Le docteur Gérard Zwang by Ferroul, Y.

    Published in Sexologies : European journal of sexology (01-07-2007)
    “…Gérard Zwang, né en 1930, a exercé la chirurgie jusqu'en 1994. Sa première intervention dans le domaine de la sexologie sera pour corriger les affirmations approximatives…”
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    Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not Polyubiquitylation by Mosesson, Yaron, Shtiegman, Keren, Katz, Menachem, Zwang, Yaara, Vereb, Gyorgi, Szollosi, Janos, Yarden, Yosef

    Published in The Journal of biological chemistry (13-06-2003)
    “…Growth factors stimulate specific receptor tyrosine kinases, but subsequent receptor endocytosis terminates signaling. The ubiquitin ligase c-Cbl targets…”
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    Sprouty Fine-Tunes EGF Signaling through Interlinked Positive and Negative Feedback Loops by Rubin, Chanan, Litvak, Vladi, Medvedovsky, Helena, Zwang, Yaara, Lev, Sima, Yarden, Yosef

    Published in Current biology (18-02-2003)
    “…Background: Growth factors and their receptor tyrosine kinases play pivotal roles in development, normal physiology, and pathology. Signal transduction is…”
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  7. 7

    Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding by Amit, Ido, Yakir, Liat, Katz, Menachem, Zwang, Yaara, Marmor, Mina D, Citri, Ami, Shtiegman, Keren, Alroy, Iris, Tuvia, Shmuel, Reiss, Yuval, Roubini, Eli, Cohen, Maya, Wides, Ron, Bacharach, Eran, Schubert, Ullrich, Yarden, Yosef

    Published in Genes & development (15-07-2004)
    “…The tumor suppressor gene 101 (tsg101) regulates vesicular trafficking processes in yeast and mammals. We report a novel protein, Tal (Tsg101-associated…”
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  8. 8

    Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation by Goldberg, Zehavit, Sionov, Ronit Vogt, Berger, Michael, Zwang, Yaara, Perets, Ruth, Van Etten, Richard A., Oren, Moshe, Taya, Yoichi, Haupt, Ygal

    Published in The EMBO journal (15-07-2002)
    “…The p53 tumor suppressor is inhibited and destabilized by Mdm2. However, under stress conditions, this downregulation is relieved, allowing the accumulation of…”
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    Polar Expression of ErbB-2/HER2 in Epithelia: Bimodal Regulation by Lin-7 by Shelly, Maya, Mosesson, Yaron, Citri, Ami, Lavi, Sara, Zwang, Yaara, Melamed-Book, Naomi, Aroeti, Benjamin, Yarden, Yosef

    Published in Developmental cell (01-09-2003)
    “…ErbB-2/HER2 drives epithelial malignancies by forming heterodimers with growth factor receptors. The primordial invertebrate receptor is sorted to the…”
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  10. 10

    Phosphorylation of Carboxyl-terminal Tyrosines Modulates the Specificity of Sprouty-2 Inhibition of Different Signaling Pathways by Rubin, Chanan, Zwang, Yaara, Vaisman, Nora, Ron, Dina, Yarden, Yosef

    Published in The Journal of biological chemistry (11-03-2005)
    “…Sprouty proteins are evolutionarily conserved negative feedback regulators of multiple receptor tyrosine kinases. Mammalian versions of these proteins…”
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    EGR1 and the ERK‐ERF axis drive mammary cell migration in response to EGF by Tarcic, Gabi, Avraham, Roi, Pines, Gur, Amit, Ido, Shay, Tal, Lu, Yiling, Zwang, Yaara, Katz, Menachem, Ben‐Chetrit, Nir, Jacob‐Hirsch, Jasmine, Virgilio, Laura, Rechavi, Gideon, Mavrothalassitis, George, Mills, Gordon B., Domany, Eytan, Yarden, Yosef

    Published in The FASEB journal (01-04-2012)
    “…The signaling pathways that commit cells to migration are incompletely understood. We employed human mammary cells and two stimuli: epidermal growth factor…”
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    942 The tumor microbiome correlates with response to immune checkpoint inhibitors in renal cell carcinoma by Wheeler, Caroline, Yang, Yuanquan, Spakowicz, Daniel, Hoyd, Rebecca, Li, Mingjia

    Published in Journal for immunotherapy of cancer (01-11-2021)
    “…BackgroundImmune checkpoint inhibitor therapy, or ICI, is currently the most successful treatment option for patients with renal cell carcinoma (RCC). However,…”
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    Revisión a la implementación de los programas de retorno. Una mirada a partir de tres estudios de caso en el Oriente Antioqueño by Ramírez Zuluaga, Luis Antonio

    Published in El ágora USB (01-07-2015)
    “…El presente artículo es producto de la investigación “Análisis de los procesos de retorno y reubicación de población en situación de desplazamiento forzado en…”
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    Alternativas de seguridad de una población víctima de desplazamiento forzado. El caso de la comuna 8 de Medellín by Angarita Cañas, Pablo E., Yepes, Cristian Ricardo

    Published in El ágora USB (01-01-2015)
    “…¿Es posible que poblaciones que viven en condiciones socioeconómicas precarias y en contextos violentos, puedan proveerse una seguridad diferente a la ofrecida…”
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  16. 16

    Effects and possible mechanisms of dexmedetomidine on post-operative cognitive dysfunction by He, Huijuan, Zhu, Manhua, Lyu, Yupeng, Yuan, Yuan, Qi, Yong

    Published in Chinese medical journal (05-10-2023)
    “…, the proportion was decreased in the POCD group, and was increased after Dex administration [Figure 1G]. 2.Meng, LLi, LLu, SLi, KSu, ZWang, Y…”
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    Epidermal Growth Factor Receptor Phosphorylation Sites Ser991 and Tyr998 Are Implicated in the Regulation of Receptor Endocytosis and Phosphorylations at Ser1039 and Thr1041 by Tong, Jiefei, Taylor, Paul, Peterman, Scott M., Prakash, Amol, Moran, Michael F.

    Published in Molecular & cellular proteomics (01-09-2009)
    “…Aberrant expression, activation, and down-regulation of the epidermal growth factor receptor (EGFR) have causal roles in many human cancers, and…”
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    Patronizing and Policing Elderly People by Giles, Howard, Zwang-Weissman, Yardena, Hajek, Christopher

    Published in Psychological reports (01-12-2004)
    “…426 students rated a vignette wherein an older person was patronized (more or less) or not by a police officer. Trait attributions were linearly related to…”
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