Search Results - "ZUSMAN, Tal"

Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal by Lifshitz, Ziv, Burstein, David, Peeri, Michael, Zusman, Tal, Schwartz, Kierstyn, Shuman, Howard A, Pupko, Tal, Segal, Gil

“…Legionella and Coxiella are intracellular pathogens that use the virulence-related Icm/Dot type-IVB secretion system to translocate effector proteins into host…”
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Genome-scale identification of Legionella pneumophila effectors using a machine learning approach by Burstein, David, Zusman, Tal, Degtyar, Elena, Viner, Ram, Segal, Gil, Pupko, Tal

“…A large number of highly pathogenic bacteria utilize secretion systems to translocate effector proteins into host cells. Using these effectors, the bacteria…”
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Identification of Legionella pneumophila Effectors Regulated by the LetAS-RsmYZ-CsrA Regulatory Cascade, Many of Which Modulate Vesicular Trafficking by Nevo, Oded, Zusman, Tal, Rasis, Michal, Lifshitz, Ziv, Segal, Gil

“…Legionella pneumophila, the causative agent of Legionnaires' disease, is an intracellular human pathogen that utilizes the Icm/Dot type IVB secretion system to…”
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The single‐domain response regulator LerC functions as a connector protein in the Legionella pneumophila effectors regulatory network by Feldheim, Yaron S., Zusman, Tal, Kapach, Anya, Segal, Gil

“…Summary The intracellular pathogen Legionella pneumophila translocates more than 300 effector proteins into host cells during infection. The PmrAB…”
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response regulator PmrA is a major regulator of the icm/dot type IV secretion system in Legionella pneumophila and Coxiella burnetii by Zusman, Tal, Aloni, Gali, Halperin, Einat, Kotzer, Hani, Degtyar, Elena, Feldman, Michal, Segal, Gil

“…Legionella pneumophila and Coxiella burnetii have been shown to utilize the icm/dot type IV secretion system for pathogenesis and recently a large number of…”
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The Legionella genus core effectors display functional conservation among orthologs by themselves or combined with an accessory protein by Wexler, Michael, Zusman, Tal, Linsky, Marika, Lifshitz, Ziv, Segal, Gil

“…•The Legionella genus contains nine core effectors.•Three Legionella pneumophila core effectors are required for intracellular growth.•The Legionella genus…”
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Identification of a Hypervariable Region Containing New Legionella pneumophila Icm/Dot Translocated Substrates by Using the Conserved icmQ Regulatory Signature by Zusman, Tal, Degtyar, Elena, Segal, Gil

“…Legionella pneumophila is an intracellular pathogen that has been shown to utilize the Icm/Dot type IV secretion system for pathogenesis. This system was shown…”
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Functional Similarities between the icm/dot Pathogenesis Systems of Coxiella burnetii and Legionella pneumophila by ZUSMAN, Tal, YERUSHALMI, Gal, SEGAL, Gil

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Characterization of a Legionella pneumophila relA Insertion Mutant and Roles of RelA and RpoS in Virulence Gene Expression by Zusman, Tal, Gal-Mor, Ohad, Segal, Gil

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Coevolution between Nonhomologous but Functionally Similar Proteins and Their Conserved Partners in the Legionella Pathogenesis System by Feldman, Michal, Zusman, Tal, Hagag, Shelly, Segal, Gil

“…Legionella pneumophila, the causative agent of Legionnaires' disease, and other pathogenic Legionella species multiply inside protozoa and human macrophages by…”
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Characterization of the icmH and icmF Genes Required for Legionella pneumophila Intracellular Growth, Genes That Are Present in Many Bacteria Associated with Eukaryotic Cells by ZUSMAN, Tal, FELDMAN, Michal, HALPERIN, Einat, SEGAL, Gil

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Additive Effect on Intracellular Growth by Legionella pneumophila Icm/Dot Proteins Containing a Lipobox Motif by Yerushalmi, Gal, Zusman, Tal, Segal, Gil

“…Legionella pneumophila, the causative agent of Legionnaires' disease, utilizes a type IVB secretion system to subvert its host cells and grow intracellularly…”
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The LysR‐type transcriptional regulator LelA co‐regulates various effectors in different Legionella species by Shapira, Naomi, Zusman, Tal, Segal, Gil

“…The intracellular pathogen Legionella pneumophila translocates more than 300 effector proteins into its host cells. The expression levels of the genes encoding…”
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Analysis of DNA Regulatory Elements Required for Expression of the Legionella pneumophila icm and dot Virulence Genes by Gal-Mor, Ohad, Zusman, Tal, Segal, Gil

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Study of Legionella Effector Domains Revealed Novel and Prevalent Phosphatidylinositol 3-Phosphate Binding Domains by Nachmias, Nimrod, Zusman, Tal, Segal, Gil

“…and other species replicate intracellularly using the Icm/Dot type IV secretion system. In this system translocates >300 effectors into host cells and in the…”
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Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires by Burstein, David, Amaro, Francisco, Zusman, Tal, Lifshitz, Ziv, Cohen, Ofir, Gilbert, Jack A, Pupko, Tal, Shuman, Howard A, Segal, Gil

“…Gil Segal, Howard Shuman and colleagues sequence the genomes of 38 Legionella species and analyze 5,885 predicted effector proteins. Their analysis identifies…”
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Acute and chronic pain in orofacial trauma patients by Khan, Junad, Zusman, Tal, Wang, Qian, Eliav, Eli

“…Trauma or injury to the dentition and supporting tissues is associated with pain and discomfort, as expected, that may present immediately, shortly afterwards,…”
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Acute and Chronic Pain in Orofacial Trauma Patients by Khan, Junad, Zusman, Tal, Wang, Qian, Eliav, Eli

“…Trauma or injury to the dentition and supporting tissues is associated with pain and discomfort, as expected, that may present immediately, shortly afterwards,…”
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Two Fis regulators directly repress the expression of numerous effector-encoding genes in Legionella pneumophila by Zusman, Tal, Speiser, Yariv, Segal, Gil

“…Legionella pneumophila is an intracellular human pathogen that utilizes the Icm/Dot type IVB secretion system to translocate a large repertoire of effectors…”
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The Legionella pneumophila Incomplete Phosphotransferase System Is Required for Optimal Intracellular Growth and Maximal Expression of PmrA-Regulated Effectors by Speiser, Yariv, Zusman, Tal, Pasechnek, Anna, Segal, Gil

“…The nitrogen phosphotransferase system (PTS ) is a regulatory cascade present in many bacteria, where it controls different functions. This system is usually…”
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