Search Results - "ZUSINAITE, Eva"

Potential Antiviral Options against SARS-CoV-2 Infection by Ianevski, Aleksandr, Yao, Rouan, Fenstad, Mona Høysæter, Biza, Svetlana, Zusinaite, Eva, Reisberg, Tuuli, Lysvand, Hilde, Løseth, Kirsti, Landsem, Veslemøy Malm, Malmring, Janne Fossum, Oksenych, Valentyn, Erlandsen, Sten Even, Aas, Per Arne, Hagen, Lars, Pettersen, Caroline H., Tenson, Tanel, Afset, Jan Egil, Nordbø, Svein Arne, Bjørås, Magnar, Kainov, Denis E.

“…As of June 2020, the number of people infected with severe acute respiratory coronavirus 2 (SARS-CoV-2) continues to skyrocket, with more than 6.7 million…”
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Antiviral efficacy of cerium oxide nanoparticles by Nefedova, Alexandra, Rausalu, Kai, Zusinaite, Eva, Vanetsev, Alexander, Rosenberg, Merilin, Koppel, Kairi, Lilla, Stevin, Visnapuu, Meeri, Smits, Krisjanis, Kisand, Vambola, Tätte, Tanel, Ivask, Angela

“…Nanomaterials are prospective candidates for the elimination of viruses due to their multimodal mechanisms of action. Here, we tested the antiviral potential…”
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Novel Antiviral Activities of Obatoclax, Emetine, Niclosamide, Brequinar, and Homoharringtonine by Andersen, Petter I., Krpina, Klara, Ianevski, Aleksandr, Shtaida, Nastassia, Jo, Eunji, Yang, Jaewon, Koit, Sandra, Tenson, Tanel, Hukkanen, Veijo, Anthonsen, Marit W., Bjoras, Magnar, Evander, Magnus, Windisch, Marc P., Zusinaite, Eva, Kainov, Denis E.

“…Viruses are the major causes of acute and chronic infectious diseases in the world. According to the World Health Organization, there is an urgent need for…”
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Low Temperature and Low UV Indexes Correlated with Peaks of Influenza Virus Activity in Northern Europe during 2010⁻2018 by Ianevski, Aleksandr, Zusinaite, Eva, Shtaida, Nastassia, Kallio-Kokko, Hannimari, Valkonen, Miia, Kantele, Anu, Telling, Kaidi, Lutsar, Irja, Letjuka, Pille, Metelitsa, Natalja, Oksenych, Valentyn, Dumpis, Uga, Vitkauskiene, Astra, Stašaitis, Kestutis, Öhrmalm, Christina, Bondeson, Kåre, Bergqvist, Anders, Cox, Rebecca J, Tenson, Tanel, Merits, Andres, Kainov, Denis E

“…With the increasing pace of global warming, it is important to understand the role of meteorological factors in influenza virus (IV) epidemics. In this study,…”
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Boosted production of antibodies that neutralized different SARS-CoV-2 variants in a COVID-19 convalescent following messenger RNA vaccination - a case study by Ravlo, Erlend, Ianevski, Aleksandr, Starheim, Eirin, Wang, Wei, Ji, Ping, Lysvand, Hilde, Smura, Teemu, Kivi, Gaily, Voolaid, Maia-Liisa, Plaan, Kati, Ustav, Mart, Ustav, Mart, Zusinaite, Eva, Tenson, Tanel, Kurg, Reet, Oksenych, Valentyn, Walstad, Kirsti, Nordbø, Svein Arne, Kaarbø, Mari, Ernits, Karin, Bjørås, Magnar, Kainov, Denis E., Fenstad, Mona Høysæter

“…•Messenger RNA vaccination boosted the production of serum anti-SARS-CoV-2 antibodies.•The antibodies neutralized strains of 19A, 20A, 20B, 20H, 21J, and 21K…”
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Novel Synergistic Anti-Enteroviral Drug Combinations by Ianevski, Aleksandr, Zusinaite, Eva, Tenson, Tanel, Oksenych, Valentyn, Wang, Wei, Afset, Jan Egil, Bjørås, Magnar, Kainov, Denis E

“…Background: Enterovirus infections affect people around the world, causing a range of illnesses, from mild fevers to severe, potentially fatal conditions…”
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N -glycosylation in the Pre-Membrane Protein Is Essential for the Zika Virus Life Cycle by Gwon, Yong-Dae, Zusinaite, Eva, Merits, Andres, Överby, Anna K, Evander, Magnus

“…Asparagine (N)-linked protein glycosylation plays an important role in protein synthesis and modification. Two Zika virus (ZIKV) structural proteins, the…”
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Common Nodes of Virus-Host Interaction Revealed Through an Integrated Network Analysis by Bösl, Korbinian, Ianevski, Aleksandr, Than, Thoa T, Andersen, Petter I, Kuivanen, Suvi, Teppor, Mona, Zusinaite, Eva, Dumpis, Uga, Vitkauskiene, Astra, Cox, Rebecca J, Kallio-Kokko, Hannimari, Bergqvist, Anders, Tenson, Tanel, Merits, Andres, Oksenych, Valentyn, Bjørås, Magnar, Anthonsen, Marit W, Shum, David, Kaarbø, Mari, Vapalahti, Olli, Windisch, Marc P, Superti-Furga, Giulio, Snijder, Berend, Kainov, Denis, Kandasamy, Richard K

“…Viruses are one of the major causes of acute and chronic infectious diseases and thus a major contributor to the global burden of disease. Several studies have…”
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A single-dose intranasal live-attenuated codon deoptimized vaccine provides broad protection against SARS-CoV-2 and its variants by Liu, Xiang, Ng, Wern Hann, Zusinaite, Eva, Freitas, Joseph, Taylor, Adam, Yerragunta, Venugopal, Aavula, Shukra Madhaha, Gorriparthi, Sambaiah, Ponsekaran, Santhakumar, Bonda, Rama Lakshmi, Mani, Priyanka, Nimmagadda, Sridevi V., Wang, Sainan, Lello, Laura Sandra, Zaid, Ali, Dua, Ujjwal, Taft-Benz, Sharon A., Anderson, Elizabeth, Baxter, Victoria K., Sarkar, Sanjay, Ling, Zheng L., Ashhurst, Thomas M., Cheng, Samuel M. S., Pattnaik, Priyabrata, Kanakasapapathy, Anand Kumar, Baric, Ralph S., Burt, Felicity J., Peiris, Malik, Heise, Mark T., King, Nicholas J. C., Merits, Andres, Lingala, Rajendra, Mahalingam, Suresh

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) continues its significant health and economic impact globally. Despite the success of…”
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Identification and Tracking of Antiviral Drug Combinations by Ianevski, Aleksandr, Yao, Rouan, Biza, Svetlana, Zusinaite, Eva, Mannik, Andres, Kivi, Gaily, Planken, Anu, Kurg, Kristiina, Tombak, Eva-Maria, Ustav, Mart, Shtaida, Nastassia, Kulesskiy, Evgeny, Jo, Eunji, Yang, Jaewon, Lysvand, Hilde, Løseth, Kirsti, Oksenych, Valentyn, Aas, Per Arne, Tenson, Tanel, Vitkauskienė, Astra, Windisch, Marc P., Fenstad, Mona Høysæter, Nordbø, Svein Arne, Ustav, Mart, Bjørås, Magnar, Kainov, Denis E.

“…Combination therapies have become a standard for the treatment for HIV and hepatitis C virus (HCV) infections. They are advantageous over monotherapies due to…”
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Nafamostat-Interferon-α Combination Suppresses SARS-CoV-2 Infection In Vitro and In Vivo by Cooperatively Targeting Host TMPRSS2 by Ianevski, Aleksandr, Yao, Rouan, Lysvand, Hilde, Grødeland, Gunnveig, Legrand, Nicolas, Oksenych, Valentyn, Zusinaite, Eva, Tenson, Tanel, Bjørås, Magnar, Kainov, Denis E

“…SARS-CoV-2 and its vaccine/immune-escaping variants continue to pose a serious threat to public health due to a paucity of effective, rapidly deployable, and…”
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Long-Term Elevated Inflammatory Protein Levels in Asymptomatic SARS-CoV-2 Infected Individuals by Tserel, Liina, Jõgi, Piia, Naaber, Paul, Maslovskaja, Julia, Häling, Annika, Salumets, Ahto, Zusinaite, Eva, Soeorg, Hiie, Lättekivi, Freddy, Ingerainen, Diana, Soots, Mari, Toompere, Karolin, Kaarna, Katrin, Kisand, Kai, Lutsar, Irja, Peterson, Pärt

“…The clinical features of SARS-CoV-2 infection range from asymptomatic to severe disease with life-threatening complications. Understanding the persistence of…”
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Active Components of Commonly Prescribed Medicines Affect Influenza A Virus-Host Cell Interaction: A Pilot Study by Ianevski, Aleksandr, Yao, Rouan, Zusinaite, Eva, Lysvand, Hilde, Oksenych, Valentyn, Tenson, Tanel, Bjørås, Magnar, Kainov, Denis

“…Every year, millions of people are hospitalized and thousands die from influenza A virus (FLUAV) infection. Most cases of hospitalizations and death occur…”
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Synergistic Interferon-Alpha-Based Combinations for Treatment of SARS-CoV-2 and Other Viral Infections by Ianevski, Aleksandr, Yao, Rouan, Zusinaite, Eva, Lello, Laura Sandra, Wang, Sainan, Jo, Eunji, Yang, Jaewon, Ravlo, Erlend, Wang, Wei, Lysvand, Hilde, Løseth, Kirsti, Oksenych, Valentyn, Tenson, Tanel, Windisch, Marc P, Poranen, Minna M, Nieminen, Anni I, Nordbø, Svein Arne, Fenstad, Mona Høysæter, Grødeland, Gunnveig, Aukrust, Pål, Trøseid, Marius, Kantele, Anu, Lastauskienė, Eglė, Vitkauskienė, Astra, Legrand, Nicolas, Merits, Andres, Bjørås, Magnar, Kainov, Denis E

“…There is an urgent need for new antivirals with powerful therapeutic potential and tolerable side effects. Here, we tested the antiviral properties of…”
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Antiviral efficacy of nanomaterial-treated textiles in real-life like exposure conditions by Nefedova, Alexandra, Rausalu, Kai, Zusinaite, Eva, Kisand, Vambola, Kook, Mati, Smits, Krisjanis, Vanetsev, Alexander, Ivask, Angela

“…Due to the growing interest towards reducing the number of potentially infectious agents on critical high-touch surfaces, the popularity of antimicrobially and…”
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Mono- and combinational drug therapies for global viral pandemic preparedness by Ianevski, Aleksandr, Yao, Rouan, Simonsen, Ronja M., Myhre, Vegard, Ravlo, Erlend, Kaynova, Gerda D., Zusinaite, Eva, White, Judith M., Polyak, Stephen J., Oksenych, Valentyn, Windisch, Marc P., Pan, Qiuwei, Lastauskienė, Eglė, Vitkauskienė, Astra, Matukevičius, Algimantas, Tenson, Tanel, Bjørås, Magnar, Kainov, Denis E.

“…Broadly effective antiviral therapies must be developed to be ready for clinical trials, which should begin soon after the emergence of new life-threatening…”
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Development of a luciferase-based system for the detection of ZnT8 autoantibodies by Ustinova, Julia, Zusinaite, Eva, Utt, Meeme, Metsküla, Kaja, Reimand, Koit, Huchaiah, Vimala, Merits, Andres, Uibo, Raivo

“…Appearance of autoantibodies represents the first detectable sign of autoimmune destruction of beta cells in type 1 diabetes (T1D). In addition, autoantibody…”
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A Systems Approach to Study Immuno- and Neuro-Modulatory Properties of Antiviral Agents by Zusinaite, Eva, Ianevski, Aleksandr, Niukkanen, Diana, Poranen, Minna M, Bjørås, Magnar, Afset, Jan Egil, Tenson, Tanel, Velagapudi, Vidya, Merits, Andres, Kainov, Denis E

“…There are dozens of approved, investigational and experimental antiviral agents. Many of these agents cause serious side effects, which can only be revealed…”
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A new high-content screening assay of the entire hepatitis B virus life cycle identifies novel antivirals by Yang, Jaewon, König, Alexander, Park, Soonju, Jo, Eunji, Sung, Pil Soo, Yoon, Seung Kew, Zusinaite, Eva, Kainov, Denis, Shum, David, Windisch, Marc Peter

“…Chronic hepatitis B is an incurable disease. Addressing the unmet medical need for therapies has been hampered by a lack of suitable cell culture models to…”
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Phosphorylation Sites in the Hypervariable Domain in Chikungunya Virus nsP3 Are Crucial for Viral Replication by Teppor, Mona, Žusinaite, Eva, Merits, Andres

“…Chikungunya virus (CHIKV, family ) is a mosquito-transmitted alphavirus. The positive-sense RNA genome of CHIKV encodes four nonstructural proteins (nsP1 to…”
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