Search Results - "ZURGIL, Naomi"

Discrimination of leukemic Jurkat cells from normal lymphocytes via novo label-free cytometry based on fluctuation of image gray values by Wohl, Ishay, Zurgil, Naomi, Hakuk, Yaron, Sobolev, Maria, Deutsch, Mordechai

“…We introduce a simple, label-free cytometry technique, based on the spatio-temporal fluctuation analysis of pixel gray levels of a cell image utilizing the…”
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A polymer microstructure array for the formation, culturing, and high throughput drug screening of breast cancer spheroids by Markovitz-Bishitz, Yael, Tauber, Yishay, Afrimzon, Elena, Zurgil, Naomi, Sobolev, Maria, Shafran, Yana, Deutsch, Assaf, Howitz, Steffen, Deutsch, Mordechai

“…Abstract Multicellular spheroid models have been recognized as superior to monolayer cell cultures in antitumor drug screening, but their commercial adaptation…”
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Fluctuation of Information Entropy Measures in Cell Image by Wohl, Ishay, Zurgil, Naomi, Hakuk, Yaron, Sobolev, Maria, Deutsch, Mordechai

“…A simple, label-free cytometry technique is introduced. It is based on the analysis of the fluctuation of image Gray Level Information Entropy (GLIE) which is…”
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Real-time quantification of protein expression and translocation at individual cell resolution using imaging-dish-based live cell array by Ravid-Hermesh, Orit, Zurgil, Naomi, Shafran, Yana, Sobolev, Maria, Galmidi, Moti, Badihi, Yoav, Israel, Liron Limor, Lellouche, Jean Paul, Lellouche, Emmanuel, Michaeli, Shulamit, Deutsch, Mordechai

“…Cell populations represent intrinsically heterogeneous systems with a high level of spatiotemporal complexity. Monitoring and understanding cell-to-cell…”
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Intracellular esterase activity in living cells may distinguish between metastatic and tumor-free lymph nodes by Afrimzon, Elena, Deutsch, Assaf, Shafran, Yana, Zurgil, Naomi, Sandbank, Judith, Pappo, Itzhak, Deutsch, Mordechai

“…Background One of the major clinical problems in breast cancer detection is the relatively high incidence of occult lymph node metastases undetectable by…”
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Concomitant real-time monitoring of intracellular reactive oxygen species and mitochondrial membrane potential in individual living promonocytic cells by Zurgil, Naomi, Shafran, Yana, Afrimzon, Elena, Fixler, Dror, Shainberg, Asher, Deutsch, Mordechai

“…Reactive oxygen species (ROS) have recently been shown to be involved in multiple physiological responses through modulation of signaling pathways…”
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The individual-cell-based cryo-chip for the cryopreservation, manipulation and observation of spatially identifiable cells. I: methodology by Deutsch, Mordechai, Afrimzon, Elena, Namer, Yaniv, Shafran, Yana, Sobolev, Maria, Zurgil, Naomi, Deutsch, Assaf, Howitz, Steffen, Greuner, Martin, Thaele, Michael, Zimmermann, Heiko, Meiser, Ina, Ehrhart, Friederike

“…Cryopreservation is the only widely applicable method of storing vital cells for nearly unlimited periods of time. Successful cryopreservation is essential for…”
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Functional analysis of individual cells and microenvironment of breast cancer‐draining lymph nodes by Zurgil, Naomi, Deutsch, Assaf, Afrimzon, Elena, Shafran, Yana, Tirosh, Reuven, Sandbank, Judith, Pappo, Itzhak, Deutsch, Mordechai

“…The development of distant metastases is the major cause of death in breast cancer (BC). In many BC cases, metastases are present in patients with no…”
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The Induction of Apoptosis by Methotrexate in Activated Lymphocytes as Indicated by Fluorescence Hyperpolarization: a Possible Model for Predicting Methotrexate Therapy for Rheumatoid Arthritis Patients by Herman, Shoshy, Zurgil, Naomi, Langevitz, Pnina, Ehrenfeld, Michael, Deutsch, Mordechai

“…The objectives of this study were to test the in vitro response of healthy non-activated, activated, and rheumatoid arthritis (RA) lymphocytes to methotrexate…”
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The information-theory analysis of Michaelis–Menten constants for detection of breast cancer by Blokh, David, PhD, Stambler, Ilia, MA, Afrimzon, Elena, PhD, Shafran, Yana, MSc, Korech, Eden, MSc, Sandbank, Judith, MD, Orda, Ruben, MD, Zurgil, Naomi, PhD, Deutsch, Mordechai, PhD

“…Abstract Background: The Michaelis–Menten constants ( Km and Vmax ) operated by the Information Theory were employed for detection of breast cancer. Methods :…”
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Monitoring of Intracellular Enzyme Kinetic Characteristics of Peripheral Mononuclear Cells in Breast Cancer Patients by AFRIMZON, Elena, ZURGIL, Naomi, SHAFRAN, Yana, SANDBANK, Judith, ORDA, Ruben, LALCHUK, Shlomo, DEUTSCH, Mordechai

“…A new methodology for the detection of functional response of peripheral blood mononuclear cells against breast cancer (BC) antigens was developed. The method…”
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Spatial-temporal correlations in the speckle pattern for the characterization of cellular motion within a 3D object by Weil, Yonni, Shafran, Yana, Sobolev, Maria, Afrimzon, Elena, Zurgil, Naomi, Deutsch, Motti, Schiffer, Zeev

“…Dynamic light scattering analysis has been demonstrated recently to be a promising tool for the assessment of structural changes taking place inside opaque…”
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Co-culture hydrogel micro-chamber array-based plate for anti-tumor drug development at single-element resolution by Shafran, Yana, Deutsch, Mordechai, Afrimzon, Elena, Ravid-Hermesh, Orit, Sobolev, Maria, Bar-On-Eizig, Zehavit, Shainberg, Asher, Zurgil, Naomi

“…In response to the need for reliable cellular models that reflect complex tumor microenvironmental properties, and enable more precise testing of anti-cancer…”
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Fluorophore spectroscopy in aqueous glycerol solution: the interactions of glycerol with the fluorophore by Feldman, Haim, Iron, Mark A, Fixler, Dror, Moshkov, Sergei, Zurgil, Naomi, Afrimzon, Elena, Deutsch, Mordechai

“…A common perception exists that glycerol provides an inert-like environment modifying viscosity and index of refraction by its various concentrations in…”
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The Trace and Subgrouping of Lymphocyte Activation by Dynamic Fluorescence Intensity and Polarization Measurements by Sunray, Merav, Kaufman, Menachem, Zurgil, Naomi, Deutsch, Mordechai

“…Cell activation involves conformational changes of cytosolic enzymes, and/or their regulatory proteins, as well as intracellular matrix re-organization. In…”
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Determination of cellular thiol levels in individual viable lymphocytes by means of fluorescence intensity and polarization by Zurgil, Naomi, Kaufman, Menachem, Solodiev, Inna, Deutsch, Mordechai

“…Cellular thiol levels regulate lymphocyte proliferation and death and play a significant role in the immune response. Therefore, the ability to analyze the…”
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Measurement of Water Saturation in Soybean Oil by Galmidi, Bat-Sheva, Iron, Mark A., Zurgil, Naomi, Deutsch, Mordechai

“…In a previous study, it was observed that survivability was low when attempting to cryopreserve sperm cells in a nanoliter-sized droplet protected under…”
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Photobleaching of fluorescein as a probe for oxidative stress in single cells by Platkov, Max, Tirosh, Reuven, Kaufman, Menahem, Zurgil, Naomi, Deutsch, Mordechai

“…•Fluorescein photobleaching is controlled and used to detect intracellular ROS.•Unexpectedly, low ROS concentration slows photobleaching in cells.•Higher ROS…”
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Nitric oxide is cytoprotective to breast cancer spheroids vulnerable to estrogen-induced apoptosis by Shafran, Yana, Zurgil, Naomi, Ravid-Hermesh, Orit, Sobolev, Maria, Afrimzon, Elena, Hakuk, Yaron, Shainberg, Asher, Deutsch, Mordechai

“…Estrogen-induced apoptosis has become a successful treatment for postmenopausal metastatic, estrogen receptor-positive breast cancer. Nitric oxide involvement…”
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In situ label-free static cytometry by monitoring spatiotemporal fluctuations of image gray values by Wohl, Ishay, Zurgil, Naomi, Hakuk, Yaron, Sobolev, Maria, Galmidi, Moti, Deutsch, Mordechai

“…Spatiotemporal fluctuation of homogeneity and randomness of gray values within an image was explored and utilized as a label-free means for cell examination…”
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