Search Results - "ZUPKO, Istvan"

Chlorogenic acid and rutin play a major role in the in vivo anti-diabetic activity of Morus alba leaf extract on type II diabetic rats by Hunyadi, Attila, Martins, Ana, Hsieh, Tusty-Jiuan, Seres, Adrienn, Zupkó, István

“…The leaves of the white mulberry tree (Morus alba L.) are used worldwide in traditional medicine as anti-diabetics. Various constituents of mulberry leaves,…”
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Synthesis and Biological Application of Isosteviol-Based 1,3-Aminoalcohols by Ozsvár, Dániel, Nagy, Viktória, Zupkó, István, Szakonyi, Zsolt

“…Starting from isosteviol, a series of diterpenoid 1,3-aminoalcohol derivatives were stereoselectively synthesised. The acid-catalysed hydrolysis and…”
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Stereoselective Synthesis and Antiproliferative Activity of Steviol-Based Diterpene 1,3-Aminoalcohol Regioisomers by Bai, Dorottya, Schelz, Zsuzsanna, Boncz, Mária Fanni, Zupkó, István, Szakonyi, Zsolt

“…A series of novel diterpene-type 1,3-aminoalcohols and their regioisomers have been synthesised from natural stevioside in a stereoselective manner. The key…”
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Pauciflorins A–E, Unexpected Chromone–Monoterpene-Derived Meroterpenoids from Centrapalus pauciflorus by Krstić, Gordana, Saidu, Muhammad Bello, Bombicz, Petra, De, Sourav, Ali, Hazhmat, Zupkó, István, Berkecz, Róbert, Gallah, Umar Shehu, Rédei, Dóra, Hohmann, Judit

“…Five unusual meroterpenoids based on new carbon skeletons, pauciflorins A–E (1–5), were isolated by multistep chromatographic separations of a methanol extract…”
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Synthesis and In Vitro Anticancer Evaluation of Flavone-1,2,3-Triazole Hybrids by Németh-Rieder, Alexandra, Keglevich, Péter, Hunyadi, Attila, Latif, Ahmed Dhahir, Zupkó, István, Hazai, László

“…Hybrid compounds of flavones, namely chrysin and kaempferol, and substituted 1,2,3-triazole derivatives, were synthesized by click reaction of the intermediate…”
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Stereoselective Synthesis and Application of Gibberellic Acid-Derived Aminodiols by Khdar, Zein Alabdeen, Le, Tam Minh, Schelz, Zsuzsanna, Zupkó, István, Szakonyi, Zsolt

“…A series of gibberellic acid-based aminodiols was designed and synthesized from commercially available gibberellic acid. Exposure of gibberellic acid to…”
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Angular Regioselective Synthesis of Varied Functionalized Hexahydro-1,2,4-triazolo[4,3- a ]quinazolin-9-ones and Their Antiproliferative Action by Said, Awad I, Gajdács, Márió, Zupkó, István, Haukka, Matti, Palkó, Márta

“…New 2-thioxopyrimidin-4-ones capable of participating in regioselective reactions with functionally diverse hydrazonoyl chlorides towards angular regioisomers,…”
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Phytochemical Characterization and Evaluation of the Antimicrobial, Antiproliferative and Pro-Apoptotic Potential of Ephedra alata Decne. Hydroalcoholic Extract against the MCF-7 Breast Cancer Cell Line by Danciu, Corina, Muntean, Delia, Alexa, Ersilia, Farcas, Claudia, Oprean, Camelia, Zupko, Istvan, Bor, Andrea, Minda, Daliana, Proks, Maria, Buda, Valentina, Hancianu, Monica, Cioanca, Oana, Soica, Codruta, Popescu, Sofia, Dehelean, Cristina Adriana

“…Decne. belongs to the family. It is a species of Ephedra that grows mostly in the desert. Today, the main importance of species in the medical field is due to…”
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Synthesis and Study of the Structure-Activity Relationship of Antiproliferative N -Substituted Isosteviol-Based 1,3-Aminoalcohols by Ozsvár, Dániel, Bózsity, Noémi, Zupkó, István, Szakonyi, Zsolt

“…Starting from isosteviol, a series of diterpenoid 1,3-aminoalcohol derivatives were prepared via stereoselective transformations. The acid-catalysed hydrolysis…”
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Thymoquinone-protoflavone hybrid molecules as potential antitumor agents by Ahmed, Sara H H, Tayeb, Bizhar A, Gonda, Tímea, Girst, Gábor, Szőri, Kornél, Berkecz, Róbert, Zupkó, István, Minorics, Renáta, Hunyadi, Attila

“…We describe herein the synthesis of eight new ester-coupled hybrid compounds from thymoquinone and protoflavone building blocks, and their bioactivity testing…”
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Synthesis and Antiproliferative Effect of New Alkyne-Tethered Vindoline Hybrids Containing Pharmacophoric Fragments by Ferenczi, Etelka, Keglevich, Péter, Tayeb, Bizhar Ahmed, Minorics, Renáta, Papp, Dávid, Schlosser, Gitta, Zupkó, István, Hazai, László, Csámpai, Antal

“…In the frame of our diversity-oriented research on multitarget small molecule anticancer agents, utilizing convergent synthetic sequences terminated by…”
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Synthesis and Antiproliferative Activity of Steroidal Diaryl Ethers by Kovács, Édua, Ali, Hazhmat, Minorics, Renáta, Traj, Péter, Resch, Vivien, Paragi, Gábor, Bruszel, Bella, Zupkó, István, Mernyák, Erzsébet

“…Novel 13α-estrone derivatives have been synthesized via direct arylation of the phenolic hydroxy function. Chan-Lam couplings of arylboronic acids with…”
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Synthesis of Estrone Heterodimers and Evaluation of Their In Vitro Antiproliferative Activity by Bózsity, Noémi, Nagy, Viktória, Szabó, Johanna, Pálházi, Balázs, Kele, Zoltán, Resch, Vivien, Paragi, Gábor, Zupkó, István, Minorics, Renáta, Mernyák, Erzsébet

“…Directed structural modifications of natural products offer excellent opportunities to develop selectively acting drug candidates. Natural product hybrids…”
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Spray-dried indomethacin-loaded polymeric micelles for the improvement of intestinal drug release and permeability by Sipos, Bence, Csóka, Ildikó, Ambrus, Rita, Schelz, Zsuzsanna, Zupkó, István, Balogh, György Tibor, Katona, Gábor

“…•The spray-dried intermediate product showed proper flowability and characteristics.•Indomethacin-loaded polymeric micelle showed increased drug release.•Ex…”
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Repositioning of HMG-CoA Reductase Inhibitors as Adjuvants in the Modulation of Efflux Pump-Mediated Bacterial and Tumor Resistance by Schelz, Zsuzsanna, Muddather, Hiba F, Zupkó, István

“…Efflux pump (EP)-mediated multidrug resistance (MDR) seems ubiquitous in bacterial infections and neoplastic diseases. The diversity and lack of specificity of…”
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An In Vitro Investigation of the Antiproliferative and Antimetastatic Effects of Levosimendan: Potential Drug Repurposing for Cervical Cancer by Schelz, Zsuzsanna, Muddather, Hiba F, Jaski, Fatemeh Sheihaki, Bózsity, Noémi, Zupkó, István

“…Cervical cancer presents a significant challenge to the global health of women. Despite substantial advances in human papillomavirus (HPV)-related cervical…”
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Sesquiterpene Lactones and Flavonoids from Psephellus pyrrhoblepharus with Antiproliferative Activity on Human Gynecological Cancer Cell Lines by Tastan, Pelin, Hajdú, Zsuzsanna, Kúsz, Norbert, Zupkó, István, Sinka, Izabella, Kivcak, Bijen, Hohmann, Judit

“…Multistep chromatographic separations of the chloroform extract of the Turkish endemic plant (Boiss.) Wagenitz (syn. Boiss.) resulted in the isolation of six…”
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CuAAC-Based Synthesis, Copper-Catalyzed Aldehyde-Forming Hydrolytic Fission and Antiproliferative Evaluation of Novel Ferrocenoylamino-Substituted Triazole-Tethered Quinine-Chalcone Hybrids by Dembo, António, Ferenczi, Etelka, Jernei, Tamás, Bor, Andrea, Schelz, Zsuzsanna, Zupkó, István, Varga, Szilárd, Csámpai, Antal

“…A series of novel triazole-tethered ferrocenoylamino-substituted cinchona-chalcone hybrids along with two representative benzoylamino-substituted reference…”
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Stereoselective Synthesis and Antiproliferative Activity of Steviol-Based Diterpen Aminodiols by Ozsvár, Dániel, Nagy, Viktória, Zupkó, István, Szakonyi, Zsolt

“…A library of steviol-based trifunctional chiral ligands was developed from commercially available natural stevisoide and applied as chiral catalysts in the…”
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Chemical and colloidal stability of carboxylated core-shell magnetite nanoparticles designed for biomedical applications by Szekeres, Márta, Tóth, Ildikó Y, Illés, Erzsébet, Hajdú, Angéla, Zupkó, István, Farkas, Katalin, Oszlánczi, Gábor, Tiszlavicz, László, Tombácz, Etelka

“…Despite the large efforts to prepare super paramagnetic iron oxide nanoparticles (MNPs) for biomedical applications, the number of FDA or EMA approved…”
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