Search Results - "ZUNDEL, Wayne"

Hypoxic induction of AKAP12 variant 2 shifts PKA-mediated protein phosphorylation to enhance migration and metastasis of melanoma cells by Finger, Elizabeth C., Castellini, Laura, Rankin, Erinn B., Vilalta, Marta, Krieg, Adam J., Jiang, Dadi, Banh, Alice, Zundel, Wayne, Powell, Marianne Broome, Giaccia, Amato J.

“…Significance Scaffold proteins can serve as critical focal points for association of signaling molecules and downstream pathways that regulate tumor growth and…”
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The Emerging Role of the COP9 Signalosome in Cancer by Richardson, Katharine S, Zundel, Wayne

“…In the last several years, multiple lines of evidence have suggested that the COP9 signalosome (CSN) plays a significant role in the regulation of multiple…”
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Loss of PTEN facilitates HIF-1-mediated gene expression by Zundel, W, Schindler, C, Haas-Kogan, D, Koong, A, Kaper, F, Chen, E, Gottschalk, A R, Ryan, H E, Johnson, R S, Jefferson, A B, Stokoe, D, Giaccia, A J

“…In glioblastoma-derived cell lines, PTEN does not significantly alter apoptotic sensitivity or cause complete inhibition of DNA synthesis. However, in these…”
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Caveolin 1-Mediated Regulation of Receptor Tyrosine Kinase-Associated Phosphatidylinositol 3-Kinase Activity by Ceramide by Zundel, Wayne, Swiersz, Lillian M., Giaccia, Amato

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Macrophage migration inhibitory factor manipulation and evaluation in tumoral hypoxic adaptation by Winner, Millicent, Leng, Lin, Zundel, Wayne, Mitchell, Robert A

“…Increasingly clear is an important regulatory role for hypoxia-inducible factor 1alpha (HIF-1alpha) in the expression of the cytokine/growth factor macrophage…”
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Molecular Imaging of Hypoxia-Inducible Factor 1α and von Hippel-Lindau Interaction in Mice by Choi, Clara Y.H., Chan, Denise A., Paulmurugan, Ramasamy, Sutphin, Patrick D., Le, Quynh-Thu, Koong, Albert C., Zundel, Wayne, Gambhir, Sanjiv S., Giaccia, Amato J.

“…Tumor hypoxia plays a crucial role in tumorigenesis. Under hypoxia, hypoxia-inducible factor 1α (HIF-1α) regulates activation of genes promoting malignant…”
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Amplification of tumor hypoxic responses by macrophage migration inhibitory factor-dependent hypoxia-inducible factor stabilization by WINNER, Millicent, KOONG, Albert C, RENDON, Beatriz E, ZUNDEL, Wayne, MITCHELL, Robert A

“…Low oxygen tension-mediated transcription by hypoxia-inducible factors (HIF) has been reported to facilitate tumor progression, therapeutic resistance, and…”
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Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress by Zundel, W, Giaccia, A

“…The initiation of apoptosis often transpires in the presence of agents that regulate cell survival. This study evaluated the effects of stress-induced ceramide…”
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Mechanisms of macrophage migration inhibitory factor (MIF)-dependent tumor microenvironmental adaptation by Rendon, Beatriz E., Willer, Sharon S., Zundel, Wayne, Mitchell, Robert A.

“…Since its activity was first reported in the mid-1960s, macrophage migration inhibitory factor (MIF) has gone from a cytokine activity modulating monocyte…”
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COPing with hypoxia by Mikus, Peter, Zundel, Wayne

“…To understand how cells respond to altered oxygenation, a frequent experimental paradigm is to isolate known components of bona fide oxygen responsive…”
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Distinct aerobic and hypoxic mechanisms of HIF-alpha regulation by CSN5 by Bemis, Lynne, Chan, Denise A, Finkielstein, Carla V, Qi, Lin, Sutphin, Patrick D, Chen, Xiaojiang, Stenmark, Kurt, Giaccia, Amato J, Zundel, Wayne

“…Mammalian oxygen homeostasis is dependent on the HIF family of transcription factors. The CSN subunit, CSN5, binds both the CODD of HIF-1 alpha and the pVHL…”
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Mechanisms of macrophage migration inhibitory factor (MIF)-dependent tumor microenvironmental adaptation: Structural Biology by RENDON, Beatriz E, WILLER, Sharon S, ZUNDEL, Wayne, MITCHELL, Robert A

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THE MUSCULAR DYSTROPHIES by ZUNDEL, W S, TYLER, F H

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THE MUSCULAR DYSTROPHIES by ZUNDEL, W S, TYLER, F H

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Short Half-times of Caesium-137 in Pregnant Women by ZUNDEL, WAYNE S, TYLER, FRANK H, MAYS, CHARLES W, LLOYD, RAY D, WAGNER, WILLIAM W, PENDLETON, ROBERT C

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Short Caesium Half-times in Patients with Muscular Dystrophy by LLOYD, RAY D, ZUNDEL, WAYNE S, MAYS, CHARLES W, WAGNER, WILLIAM W, PENDLETON, ROBERT C, AAMODT, ROGER L, TYLER, FRANK H

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The role and regulation of phosphatidylinositol -3 kinase, PTEN, and AKT in tumorigenesis by Zundel, Wayne Stephan

“…The PI(3)K/PTEN/Akt pathway is altered in a majority of cancers. To address the significance of this pathway in a physiologically relevant model, I utilized…”
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Metabolism of ^{83}{\rm Rb}$ and 137 Cs in Persons with Muscle Disease by Lloyd, Ray D., Mays, Charles W., McFarland, Susan S., Zundel, Wayne S., Tyler, Frank H.

“…A double tracer of the muscle-seeking radionuclides ^{83}{\rm Rb}+{}^{137}{\rm Cs}$ was administered orally to persons of various ages, 16 with and 22 without…”
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Metabolism of 83 Rb and 137 Cs in persons with muscle disease by Lloyd, R D, Mays, C W, McFarland, S S, Zundel, W S, Tyler, F H

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