Search Results - "ZUCCHELLI, Marco"

Expression analysis of the NLRP gene family suggests a role in human preimplantation development by Zhang, Pu, Dixon, Morag, Zucchelli, Marco, Hambiliki, Fredwell, Levkov, Lev, Hovatta, Outi, Kere, Juha

“…The NLRP (Nucleotide-binding oligomerization domain, Leucine rich Repeat and Pyrin domain containing) family, also referred to as NALP family, is well known…”
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Transcriptome profiling of human pre-implantation development by Zhang, Pu, Zucchelli, Marco, Bruce, Sara, Hambiliki, Fredwell, Stavreus-Evers, Anneli, Levkov, Lev, Skottman, Heli, Kerkelä, Erja, Kere, Juha, Hovatta, Outi

“…Preimplantation development is a crucial step in early human development. However, the molecular basis of human preimplantation development is not well known…”
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Characterization of a Common Susceptibility Locus for Asthma-Related Traits by Laitinen, Tarja, Polvi, Anne, Rydman, Pia, Vendelin, Johanna, Pulkkinen, Ville, Salmikangas, Paula, Mäkelä, Siru, Rehn, Marko, Pirskanen, Asta, Rautanen, Anna, Zucchelli, Marco, Gullstén, Harriet, Leino, Marina, Alenius, Harri, Petäys, Tuula, Haahtela, Tari, Laitinen, Annika, Laprise, Catherine, Hudson, Thomas J., Laitinen, Lauri A., Kere, Juha

“…Susceptibility to asthma depends on variation at an unknown number of genetic loci. To identify susceptibility genes on chromosome 7p, we adopted a…”
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Strong Genetic Evidence of DCDC2 as a Susceptibility Gene for Dyslexia by Schumacher, Johannes, Anthoni, Heidi, Dahdouh, Faten, König, Inke R., Hillmer, Axel M., Kluck, Nadine, Manthey, Malou, Plume, Ellen, Warnke, Andreas, Remschmidt, Helmut, Hülsmann, Jutta, Cichon, Sven, Lindgren, Cecilia M., Propping, Peter, Zucchelli, Marco, Ziegler, Andreas, Peyrard-Janvid, Myriam, Schulte-Körne, Gerd, Nöthen, Markus M., Kere, Juha

“…We searched for linkage disequilibrium (LD) in 137 triads with dyslexia, using markers that span the most-replicated dyslexia susceptibility region on…”
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Evidence for Genetic Association and Interaction Between the TYK2 and IRF5 Genes in Systemic Lupus Erythematosus by HELLQUIST, Anna, JARVINEN, Tiina M, SAARIALHO-KERE, Ulpu, KERE, Juha, KOSKENMIES, Sari, ZUCCHELLI, Marco, ORSMARK-PIETRAS, Christina, BERGLIND, Linda, PANELIUS, Jaana, HASAN, Taina, JULKUNEN, Heikki, D'AMATO, Mauro

“…Objective. Several candidate genes have been implicated in susceptibility for systemic lupus erythematosus (SLE), a complex autoimmune disease. The proposed…”
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Multiple polymorphisms affect expression and function of the neuropeptide S receptor (NPSR1) by Anedda, Francesca, Zucchelli, Marco, Schepis, Danika, Hellquist, Anna, Corrado, Lucia, D'Alfonso, Sandra, Achour, Adnane, McInerney, Gerald, Bertorello, Alejandro, Lördal, Mikael, Befrits, Ragnar, Björk, Jan, Bresso, Francesca, Törkvist, Leif, Halfvarson, Jonas, Kere, Juha, D'Amato, Mauro

“…neuropeptide S (NPS) and its receptor NPSR1 act along the hypothalamic-pituitary-adrenal axis to modulate anxiety, fear responses, nociception and…”
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A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia by Anthoni, Heidi, Zucchelli, Marco, Matsson, Hans, Müller-Myhsok, Bertram, Fransson, Ingegerd, Schumacher, Johannes, Massinen, Satu, Onkamo, Päivi, Warnke, Andreas, Griesemann, Heide, Hoffmann, Per, Nopola-Hemmi, Jaana, Lyytinen, Heikki, Schulte-Körne, Gerd, Kere, Juha, Nöthen, Markus M., Peyrard-Janvid, Myriam

“…DYX3, a locus for dyslexia, resides on chromosome 2p11-p15. We have refined its location on 2p12 to a 157 kb region in two rounds of linkage disequilibrium…”
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Large-Scale Zygosity Testing Using Single Nucleotide Polymorphisms by Hannelius, Ulf, Gherman, Loreana, Mäkelä, Ville-Veikko, Lindstedt, Astrid, Zucchelli, Marco, Lagerberg, Camilla, Tybring, Gunnel, Kere, Juha, Lindgren, Cecilia M

“…A requirement for performing robust genetic and statistical analyses on twins is correctly assigned zygosities. In order to increase the power to detect small…”
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Analysis of neuropeptide S receptor gene (NPSR1) polymorphism in rheumatoid arthritis by D'Amato, Mauro, Zucchelli, Marco, Seddighzadeh, Maria, Anedda, Francesca, Lindblad, Staffan, Kere, Juha, Alfredsson, Lars, Klareskog, Lars, Padyukov, Leonid

“…Polymorphism in the neuropeptide S receptor gene NPSR1 is associated with asthma and inflammatory bowel disease. NPSR1 is expressed in the brain, where it…”
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A teratocarcinoma-like human embryonic stem cell (hESC) line and four hESC lines reveal potentially oncogenic genomic changes by Hovatta, Outi, Jaconi, Marisa, Töhönen, Virpi, Béna, Frédérique, Gimelli, Stefania, Bosman, Alexis, Holm, Frida, Wyder, Stefan, Zdobnov, Evgeny M, Irion, Olivier, Andrews, Peter W, Antonarakis, Stylianos E, Zucchelli, Marco, Kere, Juha, Feki, Anis

“…The first Swiss human embryonic stem cell (hESC) line, CH-ES1, has shown features of a malignant cell line. It originated from the only single blastomere that…”
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Identification of MAMDC1 as a candidate susceptibility gene for systemic lupus erythematosus (SLE) by Hellquist, Anna, Zucchelli, Marco, Lindgren, Cecilia M, Saarialho-Kere, Ulpu, Järvinen, Tiina M, Koskenmies, Sari, Julkunen, Heikki, Onkamo, Päivi, Skoog, Tiina, Panelius, Jaana, Räisänen-Sokolowski, Anne, Hasan, Taina, Widen, Elisabeth, Gunnarson, Iva, Svenungsson, Elisabet, Padyukov, Leonid, Assadi, Ghazaleh, Berglind, Linda, Mäkelä, Ville-Veikko, Kivinen, Katja, Wong, Andrew, Cunningham Graham, Deborah S, Vyse, Timothy J, D'Amato, Mauro, Kere, Juha

“…Systemic lupus erythematosus (SLE) is a complex autoimmune disorder with multiple susceptibility genes. We have previously reported suggestive linkage to the…”
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Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts by Ek, Weronica E, Reznichenko, Anna, Ripke, Stephan, Niesler, Beate, Zucchelli, Marco, Rivera, Natalia V, Schmidt, Peter T, Pedersen, Nancy L, Magnusson, Patrik, Talley, Nicholas J, Holliday, Elizabeth G, Houghton, Lesley, Gazouli, Maria, Karamanolis, George, Rappold, Gudrun, Burwinkel, Barbara, Surowy, Harald, Rafter, Joseph, Assadi, Ghazaleh, Li, Ling, Papadaki, Evangelia, Gambaccini, Dario, Marchi, Santino, Colucci, Rocchina, Blandizzi, Corrado, Barbaro, Raffaella, Karling, Pontus, Walter, Susanna, Ohlsson, Bodil, Tornblom, Hans, Bresso, Francesca, Andreasson, Anna, Dlugosz, Aldona, Simren, Magnus, Agreus, Lars, Lindberg, Greger, Boeckxstaens, Guy, Bellini, Massimo, Stanghellini, Vincenzo, Barbara, Giovanni, Daly, Mark J, Camilleri, Michael, Wouters, Mira M, D'Amato, Mauro

“…IBS shows genetic predisposition, but adequately powered gene-hunting efforts have been scarce so far. We sought to identify true IBS genetic risk factors by…”
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Germline Genetic Contributions to Risk for Esophageal Adenocarcinoma, Barrett's Esophagus, and Gastroesophageal Reflux by EK, Weronica E, LEVINE, David M, ROMERO, Yvonne, CHOW, Wong-Ho, MURRAY, Liam J, GAMMON, Marilie D, LIU, Geoffrey, BERNSTEIN, Leslie, CASSON, Alan G, RISCH, Harvey A, SHAHEEN, Nicholas J, BIRD, Nigel C, D'AMATO, Mauro, REID, Brian J, CORLEY, Douglas A, HARDIE, Laura J, WEIMIN YE, WU, Anna H, ZUCCHELLI, Marco, SPECTOR, Tim D, HYSI, Pirro, VAUGHAN, Thomas L, WHITEMAN, David C, PEDERSEN, Nancy L, MACGREGOR, Stuart, MAGNUSSON, Patrik K. E, BRESSO, Francesca, ONSTAD, Lynn E, SCHMIDT, Peter T, TÖRNBLOM, Hans, NORDENSTEDT, Helena

“…Esophageal adenocarcinoma (EA) is an increasingly common cancer with poor survival. Barrett's esophagus (BE) is the main precursor to EA, and every year 0.12%…”
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Association of TNFSF15 polymorphism with irritable bowel syndrome by Zucchelli, Marco, Camilleri, Michael, Andreasson, Anna Nixon, Bresso, Francesca, Dlugosz, Aldona, Halfvarson, Jonas, Törkvist, Leif, Schmidt, Peter T, Karling, Pontus, Ohlsson, Bodil, Duerr, Richard H, Simren, Magnus, Lindberg, Greger, Agreus, Lars, Carlson, Paula, Zinsmeister, Alan R, D'Amato, Mauro

“…Irritable bowel syndrome (IBS) is the most common gastrointestinal disorder, affecting more than 10% of the general population worldwide. Although a genetic…”
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Interactions between Glutathione S-Transferase P1, Tumor Necrosis Factor, and Traffic-Related Air Pollution for Development of Childhood Allergic Disease by Melén, Erik, Nyberg, Fredrik, Lindgren, Cecilia M., Berglind, Niklas, Zucchelli, Marco, Nordling, Emma, Hallberg, Jenny, Svartengren, Magnus, Morgenstern, Ralf, Kere, Juha, Bellander, Tom, Wickman, Magnus, Pershagen, Göran

“…Background: Air pollutants may induce airway inflammation and sensitization due to generation of reactive oxygen species. The genetic background to these…”
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Perturbations of Heart Development and Function in Cardiomyocytes from Human Embryonic Stem Cells with Trisomy 21 by Bosman, Alexis, Letourneau, Audrey, Sartiani, Laura, Del Lungo, Martina, Ronzoni, Flavio, Kuziakiv, Rostyslav, Tohonen, Virpi, Zucchelli, Marco, Santoni, Federico, Guipponi, Michel, Dumevska, Biljana, Hovatta, Outi, Antonarakis, Stylianos E., Jaconi, Marisa E.

“…Congenital heart defects (CHD) occur in approximately 50% of patients with Down syndrome (DS); the mechanisms for this occurrence however remain unknown. In…”
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Replication of GWAS-identified systemic lupus erythematosus susceptibility genes affirms B-cell receptor pathway signalling and strengthens the role of IRF5 in disease susceptibility in a Northern European population by Järvinen, Tiina M., Hellquist, Anna, Zucchelli, Marco, Koskenmies, Sari, Panelius, Jaana, Hasan, Taina, Julkunen, Heikki, D'Amato, Mauro, Kere, Juha

“…Objective. A large number of genes, including several not previously implicated in SLE susceptibility, have recently been identified or confirmed by…”
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Neuropeptide S Receptor Induces Neuropeptide Expression and Associates With Intermediate Phenotypes of Functional Gastrointestinal Disorders by Camilleri, Michael, Carlson, Paula, Zinsmeister, Alan R, McKinzie, Sanna, Busciglio, Irene, Burton, Duane, Zucchelli, Marco, D'Amato, Mauro

“…Background & Aims NPSR1, the receptor for neuropeptide S (NPS), is expressed by gastrointestinal (GI) enteroendocrine cells, and is involved in inflammation,…”
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Assessment of the Neuropeptide S System in Anxiety Disorders by Donner, Jonas, Haapakoski, Rita, Ezer, Sini, Melén, Erik, Pirkola, Sami, Gratacòs, Mònica, Zucchelli, Marco, Anedda, Francesca, Johansson, Lovisa E, Söderhäll, Cilla, Orsmark-Pietras, Christina, Suvisaari, Jaana, Martín-Santos, Rocío, Torrens, Marta, Silander, Kaisa, Terwilliger, Joseph D, Wickman, Magnus, Pershagen, Göran, Lönnqvist, Jouko, Peltonen, Leena, Estivill, Xavier, D'Amato, Mauro, Kere, Juha, Alenius, Harri, Hovatta, Iiris

“…Background The G protein-coupled receptor neuropeptide S receptor 1 (NPSR1) and its ligand neuropeptide S (NPS) form a signaling system mainly implicated in…”
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Genetic analysis of dyslexia candidate genes in the European cross-linguistic NeuroDys cohort by Becker, Jessica, Czamara, Darina, Scerri, Tom S, Ramus, Franck, Csépe, Valéria, Talcott, Joel B, Stein, John, Morris, Andrew, Ludwig, Kerstin U, Hoffmann, Per, Honbolygó, Ferenc, Tóth, Dénes, Fauchereau, Fabien, Bogliotti, Caroline, Iannuzzi, Stéphanie, Chaix, Yves, Valdois, Sylviane, Billard, Catherine, George, Florence, Soares-Boucaud, Isabelle, Gérard, Christophe-Loïc, van der Mark, Sanne, Schulz, Enrico, Vaessen, Anniek, Maurer, Urs, Lohvansuu, Kaisa, Lyytinen, Heikki, Zucchelli, Marco, Brandeis, Daniel, Blomert, Leo, Leppänen, Paavo H T, Bruder, Jennifer, Monaco, Anthony P, Müller-Myhsok, Bertram, Kere, Juha, Landerl, Karin, Nöthen, Markus M, Schulte-Körne, Gerd, Paracchini, Silvia, Peyrard-Janvid, Myriam, Schumacher, Johannes

“…Dyslexia is one of the most common childhood disorders with a prevalence of around 5-10% in school-age children. Although an important genetic component is…”
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