Search Results - "ZUANG, Valérie"

Current EU regulatory requirements for the assessment of chemicals and cosmetic products: challenges and opportunities for introducing new approach methodologies by Pistollato, Francesca, Madia, Federica, Corvi, Raffaella, Munn, Sharon, Grignard, Elise, Paini, Alicia, Worth, Andrew, Bal-Price, Anna, Prieto, Pilar, Casati, Silvia, Berggren, Elisabet, Bopp, Stephanie K, Zuang, Valérie

“…The EU Directive 2010/63/EU   on the protection of animals used for scientific purposes and other EU regulations, such as REACH and the Cosmetic Products…”
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International regulatory requirements for skin sensitization testing by Daniel, Amber B., Strickland, Judy, Allen, David, Casati, Silvia, Zuang, Valérie, Barroso, João, Whelan, Maurice, Régimbald-Krnel, M.J., Kojima, Hajime, Nishikawa, Akiyoshi, Park, Hye-Kyung, Lee, Jong Kwon, Kim, Tae Sung, Delgado, Isabella, Rios, Ludmila, Yang, Ying, Wang, Gangli, Kleinstreuer, Nicole

“…Skin sensitization test data are required or considered by chemical regulation authorities around the world. These data are used to develop product hazard…”
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Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods by Adriaens, Els, Barroso, João, Eskes, Chantra, Hoffmann, Sebastian, McNamee, Pauline, Alépée, Nathalie, Bessou-Touya, Sandrine, De Smedt, Ann, De Wever, Bart, Pfannenbecker, Uwe, Tailhardat, Magalie, Zuang, Valérie

“…For more than two decades, scientists have been trying to replace the regulatory in vivo Draize eye test by in vitro methods, but so far only partial…”
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Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010 by Adler, Sarah, Basketter, David, Creton, Stuart, Pelkonen, Olavi, van Benthem, Jan, Zuang, Valérie, Andersen, Klaus Ejner, Angers-Loustau, Alexandre, Aptula, Aynur, Bal-Price, Anna, Benfenati, Emilio, Bernauer, Ulrike, Bessems, Jos, Bois, Frederic Y., Boobis, Alan, Brandon, Esther, Bremer, Susanne, Broschard, Thomas, Casati, Silvia, Coecke, Sandra, Corvi, Raffaella, Cronin, Mark, Daston, George, Dekant, Wolfgang, Felter, Susan, Grignard, Elise, Gundert-Remy, Ursula, Heinonen, Tuula, Kimber, Ian, Kleinjans, Jos, Komulainen, Hannu, Kreiling, Reinhard, Kreysa, Joachim, Leite, Sofia Batista, Loizou, George, Maxwell, Gavin, Mazzatorta, Paolo, Munn, Sharon, Pfuhler, Stefan, Phrakonkham, Pascal, Piersma, Aldert, Poth, Albrecht, Prieto, Pilar, Repetto, Guillermo, Rogiers, Vera, Schoeters, Greet, Schwarz, Michael, Serafimova, Rositsa, Tähti, Hanna, Testai, Emanuela, van Delft, Joost, van Loveren, Henk, Vinken, Mathieu, Worth, Andrew, Zaldivar, José-Manuel

“…The 7th amendment to the EU Cosmetics Directive prohibits to put animal-tested cosmetics on the market in Europe after 2013. In that context, the European…”
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A proposed eye irritation testing strategy to reduce and replace in vivo studies using Bottom–Up and Top–Down approaches by Scott, Laurie, Eskes, Chantra, Hoffmann, Sebastian, Adriaens, Els, Alepée, Nathalie, Bufo, Monica, Clothier, Richard, Facchini, Davide, Faller, Claudine, Guest, Robert, Harbell, John, Hartung, Thomas, Kamp, Hennicke, Varlet, Béatrice Le, Meloni, Marisa, McNamee, Pauline, Osborne, Rosemarie, Pape, Wolfgang, Pfannenbecker, Uwe, Prinsen, Menk, Seaman, Christopher, Spielmann, Horst, Stokes, William, Trouba, Kevin, Berghe, Christine Van den, Goethem, Freddy Van, Vassallo, Marco, Vinardell, Pilar, Zuang, Valérie

“…In spite of over 20 years of effort, no single in vitro assay has been developed and validated as a full regulatory replacement for the Draize Eye Irritation…”
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Bridging communities in the field of nanomedicine by Halamoda-Kenzaoui, Blanka, Baconnier, Simon, Bastogne, Thierry, Bazile, Didier, Boisseau, Patrick, Borchard, Gerrit, Borgos, Sven Even, Calzolai, Luigi, Cederbrant, Karin, Di Felice, Gabriella, Di Francesco, Tiziana, Dobrovolskaia, Marina A., Gaspar, Rogério, Gracia, Belén, Hackley, Vincent A., Leyens, Lada, Liptrott, Neill, Park, Margriet, Patri, Anil, Roebben, Gert, Roesslein, Matthias, Thürmer, René, Urbán, Patricia, Zuang, Valérie, Bremer-Hoffmann, Susanne

“…An early dialogue between nanomedicine developers and regulatory authorities are of utmost importance to anticipate quality and safety requirements for these…”
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Validation of Alternative In Vitro Methods to Animal Testing: Concepts, Challenges, Processes and Tools by Griesinger, Claudius, Desprez, Bertrand, Coecke, Sandra, Casey, Warren, Zuang, Valérie

“…This chapter explores the concepts, processes, tools and challenges relating to the validation of alternative methods for toxicity and safety testing. In…”
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ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity Function Test by Spielmann, Horst, Hoffmann, Sebastian, Liebsch, Manfred, Botham, Phil, Fentem, Julia H, Eskes, Chantra, Roguet, Roland, Cotovio, José, Cole, Thomas, Worth, Andrew, Heylings, Jon, Jones, Penny, Robles, Catherine, Kandárova, Helena, Gamer, Armin, Remmele, Marina

“…ECVAM sponsored a formal validation study on three in vitro tests for skin irritation, of which two employ reconstituted human epidermis models (EPISKIN,…”
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The 3T3 neutral red uptake phototoxicity test: Practical experience and implications for phototoxicity testing – The report of an ECVAM–EFPIA workshop by Ceridono, Mara, Tellner, Pär, Bauer, Daniel, Barroso, João, Alépée, Nathalie, Corvi, Raffaella, De Smedt, Ann, Fellows, Mick D., Gibbs, Neil K., Heisler, Eckhard, Jacobs, Abigail, Jirova, Dagmar, Jones, David, Kandárová, Helena, Kasper, Peter, Akunda, Jacqueline Kinyamu, Krul, Cyrille, Learn, Douglas, Liebsch, Manfred, Lynch, Anthony M., Muster, Wolfgang, Nakamura, Kazuichi, Nash, J. Frank, Pfannenbecker, Uwe, Phillips, Gareth, Robles, Catherine, Rogiers, Vera, Van De Water, Femke, Liminga, Ulla Wändel, Vohr, Hans-Werner, Wattrelos, Olivier, Woods, Julie, Zuang, Valérie, Kreysa, Joachim, Wilcox, Phil

“…This is the report from the “ECVAM–EFPIA workshop on 3T3 NRU Phototoxicity Test: Practical Experience and Implications for Phototoxicity Testing”, jointly…”
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The usefulness of toxicogenomics for predicting acute skin irritation on in vitro reconstructed human epidermis by Borlon, Céline, Godard, Patrice, Eskes, Chantra, Hartung, Thomas, Zuang, Valérie, Toussaint, Olivier

“…Abstract In vitro models aiming at replacing the traditional animal test for determining the skin irritation potential of a test substance have been developed,…”
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International Harmonization and Cooperation in the Validation of Alternative Methods by Barroso, João, Ahn, Il Young, Caldeira, Cristiane, Carmichael, Paul L, Casey, Warren, Coecke, Sandra, Curren, Rodger, Desprez, Bertrand, Eskes, Chantra, Griesinger, Claudius, Guo, Jiabin, Hill, Erin, Roi, Annett Janusch, Kojima, Hajime, Li, Jin, Lim, Chae Hyung, Moura, Wlamir, Nishikawa, Akiyoshi, Park, HyeKyung, Peng, Shuangqing, Presgrave, Octavio, Singer, Tim, Sohn, Soo Jung, Westmoreland, Carl, Whelan, Maurice, Yang, Xingfen, Yang, Ying, Zuang, Valérie

“…The development and validation of scientific alternatives to animal testing is important not only from an ethical perspective (implementation of 3Rs), but also…”
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The ECVAM International Validation Study on In Vitro Tests for Acute Skin Irritation : Selection of Test Chemicals by ESKES, Chantra, COLE, Thomas, HOFFMANN, Sebastian, WORTH, Andrew, COCKSHOTT, Amanda, GERNER, Ingrid, ZUANG, Valérie

“…The ECVAM-funded skin irritation validation study (SIVS) was initiated in 2003, with the aim to evaluate whether the EpiDerm, EPISKIN and the SIFT alternative…”
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ECVAM and new technologies for toxicity testing by Bouvier d'Yvoire, Michel, Bremer, Susanne, Casati, Silvia, Ceridono, Mara, Coecke, Sandra, Corvi, Raffaella, Eskes, Chantra, Gribaldo, Laura, Griesinger, Claudius, Knaut, Holger, Linge, Jens P, Roi, Annett, Zuang, Valérie

“…The development of alternative empirical (testing) and non-empirical (non-testing) methods to traditional toxicological tests for complex human health effects…”
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Practical Aspects of Designing and Conducting Validation Studies Involving Multi-study Trials by Coecke, Sandra, Bernasconi, Camilla, Bowe, Gerard, Bostroem, Ann-Charlotte, Burton, Julien, Cole, Thomas, Fortaner, Salvador, Gouliarmou, Varvara, Gray, Andrew, Griesinger, Claudius, Louhimies, Susanna, Gyves, Emilio Mendoza-de, Joossens, Elisabeth, Prinz, Maurits-Jan, Milcamps, Anne, Parissis, Nicholaos, Wilk-Zasadna, Iwona, Barroso, João, Desprez, Bertrand, Langezaal, Ingrid, Liska, Roman, Morath, Siegfried, Reina, Vittorio, Zorzoli, Chiara, Zuang, Valérie

“…This chapter focuses on practical aspects of conducting prospective in vitro validation studies, and in particular, by laboratories that are members of the…”
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Dendritic cells as a tool for the predictive identification of skin sensitisation hazard by Casati, S, Aeby, P, Basketter, D.A, Cavani, A, Gennari, A, Gerberick, G.F, Griem, P, Hartung, T, Kimber, I, Lepoittevin, J.P

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Standardisation of defined approaches for skin sensitisation testing to support regulatory use and international adoption: position of the International Cooperation on Alternative Test Methods by Casati, S., Aschberger, K., Barroso, J., Casey, W., Delgado, I., Kim, T. S., Kleinstreuer, N., Kojima, H., Lee, J. K., Lowit, A., Park, H. K., Régimbald-Krnel, M. J., Strickland, J., Whelan, M., Yang, Y., Zuang, Valérie

“…Skin sensitisation is the regulatory endpoint that has been at the centre of concerted efforts to replace animal testing in recent years, as demonstrated by…”
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First alternative method validated by a retrospective weight-of-evidence approach to replace the Draize eye test for the identification of non-irritant substances for a defined applicability domain by Hartung, Thomas, Bruner, Leon, Curren, Rodger, Eskes, Chantra, Goldberg, Alan, McNamee, Pauline, Scott, Laurie, Zuang, Valérie

“…A replacement alternative to the rabbit eye irritation test has been sought for many years. First published in 1944 by FDA toxicologist J. H. Draize, the test,…”
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Report of the EPAA―ECVAM Workshop on the Validation of Integrated Testing Strategies (ITS) by KINSNER-OVASKAINEN, Agnieszka, MAXWELL, Gavin, CORVI, Raffaella, CASATI, Silvia, DAL NEGRO, Gianni, MARREC-FAIRLEY, Monique, GRIESINGER, Claudius, HALDER, Marlies, HEISLER, Eckhard, HIRMANN, Doris, KLEENSANG, André, KOPP-SCHNEIDER, Annette, KREYSA, Joachim, LAPENNA, Silvia, MUNN, Sharon, PRIETO, Pilar, SCHECHTMAN, Len, SCHULTZ, Terry, VIDAL, Jean-Marc, WORTH, Andrew, ZUANG, Valérie, BARROSO, Joao, ADRIAENS, Els, ALEPEE, Nathalie, BERG, Ninna, BREMER, Susanne, COECKE, Sandra, COMENGES, José Z

“…The use of Integrated Testing Strategies (ITS) permits the combination of diverse types of chemical and toxicological data for the purposes of hazard…”
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Regulatory assessment of in vitro skin corrosion and irritation data within the European framework: Workshop recommendations by Eskes, Chantra, Detappe, Véronique, Koëter, Herman, Kreysa, Joachim, Liebsch, Manfred, Zuang, Valérie, Amcoff, Patric, Barroso, João, Cotovio, José, Guest, Robert, Hermann, Martina, Hoffmann, Sebastian, Masson, Philippe, Alépée, Nathalie, Arce, Luis Alfonso, Brüschweiler, Beat, Catone, Tiziana, Cihak, Rostislav, Clouzeau, Jack, D’Abrosca, Federica, Delveaux, Cédric, Derouette, Jean Paul, Engelking, Oliver, Facchini, Davide, Fröhlicher, Mirjam, Hofmann, Markus, Hopf, Nancy, Molinari, Jennifer, Oberli, Aurelia, Ott, Matthieu, Peter, Ronald, Sá-Rocha, Vanessa M., Schenk, Dominique, Tomicic, Catherine, Vanparys, Philippe, Verdon, Bernadette, Wallenhorst, Thomas, Winkler, Gian Christian, Depallens, Olivier

“…Validated in vitro methods for skin corrosion and irritation were adopted by the OECD and by the European Union during the last decade. In the EU, Switzerland…”
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The principles of weight of evidence validation of test methods and testing strategies : The report and recommendations of ECVAM workshop 58 by BALLS, Michael, AMCOFF, Patric, FENTEM, Julia, GRIBALDO, Laura, HALDER, Marlies, HARTUNG, Thomas, HOFFMANN, Sebastian, SCHECHTMAN, Leonard, SCOTT, Laurie, SPIELMANN, Horst, STOKES, William, TIRE, Raymond, BREMER, Susanne, WAGNER, Drew, ZUANG, Valérie, CASATI, Silvia, COECKE, Sandra, CLOTHIER, Richard, COMBES, Robert, CORVI, Raffaella, CURREN, Rodger, ESKES, Chantra

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