Search Results - "ZORZANO, A"

Macrophages and Mitochondria: A Critical Interplay Between Metabolism, Signaling, and the Functional Activity by Tur, J, Vico, T, Lloberas, J, Zorzano, A, Celada, A

“…Macrophages are phagocytic cells that participate in a broad range of cellular functions and they are key regulators of innate immune responses and…”
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Treatment of deep single RT2 and RT3 antero‐mandibular gingival recessions with a combination of surgical techniques: A case series study by Fernández‐Jiménez, A., García‐De‐La‐Fuente, A. M., Marichalar‐Mendia, X., Aguirre‐Zorzano, L. A., Estefanía‐Fresco, R.

“…Objective To evaluate root coverage (RC) in deep single antero‐mandibular RT2 and RT3 gingival recessions (GR) and to investigate the influence of several…”
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Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity by Bach, Daniel, Pich, Sara, Soriano, Francesc X, Vega, Nathalie, Baumgartner, Bernhard, Oriola, Josep, Daugaard, Jens R, Lloberas, Jorge, Camps, Marta, Zierath, Juleen R, Rabasa-Lhoret, Rémi, Wallberg-Henriksson, Harriet, Laville, Martine, Palacín, Manuel, Vidal, Hubert, Rivera, Francisca, Brand, Martin, Zorzano, Antonio

“…In many cells and specially in muscle, mitochondria form elongated filaments or a branched reticulum. We show that Mfn2 (mitofusin 2), a mitochondrial membrane…”
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Phenformin-induced mitochondrial dysfunction sensitizes hepatocellular carcinoma for dual inhibition of mTOR by Veiga, S., Ge, X., Mercer, C., Hernández-Álvarez, M., Thomas, H., Hernandez-Losa, J., Cajal, S.R.Y, Zorzano, A., Thomas, G., Kozma, S.

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Could the low level of expression of the gene encoding skeletal muscle mitofusin-2 account for the metabolic inflexibility of obesity? by MINGRONE, G, MANCO, M, CALVANI, M, CASTAGNETO, M, NAON, D, ZORZANO, A

“…In obesity the cellular capacity to switch from using lipid to carbohydrate and vice versa as the energy substrate, known as 'metabolic flexibility', is…”
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Adipocytes release a soluble form of VAP-1/SSAO by a metalloprotease-dependent process and in a regulated manner by ABELLA, A, GARCIA-VICENTE, S, VIGUERIE, N, ROS-BARO, A, CAMPS, M, PALACIN, M, ZORZANO, A, MARTI, L

“…Vascular adhesion protein-1 (VAP-1), which is identical to semicarbazide-sensitive amine oxidase (SSAO), is a dual-function membrane protein with adhesion…”
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Mechanisms regulating GLUT4 glucose transporter expression and glucose transport in skeletal muscle by Zorzano, A., Palacín, M., Gumà, A.

“…Skeletal muscle is a major glucose‐utilizing tissue in the absorptive state and the major glucose transporter expressed in muscle in adulthood is GLUT4. GLUT4…”
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MCJ/DnaJC15, the Mitochondrial Foe in Liver Injury by Torres, L.B, Iruzubieta, P, Taibo, D, Cardoso, T, Navasa, N, Ramos, D.F, Rey, M.V, de Juan, V.G, Tussy, P.F, Franco, I.Z, Alvarez, M.I.H, Andrade, R, Medina, I, Monte, M.J, Marín, J.J.G, Crespo, J, Zorzano, A, Mato, J.M, Anguita, J, Rincon, M, Chantar, M.L.M

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The DEXLIFE study methods: Identifying novel candidate biomarkers that predict progression to type 2 diabetes in high risk individuals by Andersen, G.S, Thybo, T, Cederberg, H, Orešič, M, Esteller, M, Zorzano, A, Carr, B, Walker, M, Cobb, J, Clissmann, C, O’Gorman, D.J, Nolan, J.J

“…Abstract The incidence of type 2 diabetes (T2D) is rapidly increasing worldwide and T2D is likely to affect 592 million people in 2035 if the current rate of…”
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Central venous catheter colonization with Staphylococcus aureus is not always an indication for antimicrobial therapy by Muñoz, P., Fernández Cruz, A., Usubillaga, R., Zorzano, A., Rodríguez-Créixems, M., Guembe, M., Bouza, E.

“…Whether patients whose catheter tip grows Staphylococcus aureus but who have no concomitant bacteraemia should receive antimicrobials remains an unresolved…”
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Genes involved in mitochondrial biogenesis/function are induced in response to bilio-pancreatic diversion in morbidly obese individuals with normal glucose tolerance but not in type 2 diabetic patients by Hernández-Alvarez, M. I, Chiellini, C, Manco, M, Naon, D, Liesa, M, Palacín, M, Mingrone, G, Zorzano, A

“…Aims/hypothesis The mechanisms allowing normalisation of insulin sensitivity and reversal of type 2 diabetes after bilio-pancreatic diversion (BPD) have not…”
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Protection from inflammatory disease in insulin resistance: the role of mannan-binding lectin by Fernández-Real, J. M, Straczkowski, M, Vendrell, J, Soriguer, F, Pérez del Pulgar, S, Gallart, L, López-Bermejo, A, Kowalska, I, Manco, M, Cardona, F, García-Gil, M. M, Mingrone, G, Richart, C, Ricart, W, Zorzano, A

“…Aims/hypothesis Decreased sensing of the innate immune system may lead to chronic activation of the inflammatory cascade. We hypothesised that mannan-binding…”
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Semicarbazide-sensitive amine oxidase activity exerts insulin-like effects on glucose metabolism and insulin-signaling pathways in adipose cells by Zorzano, Antonio, Abella, Anna, Marti, Luc, Carpéné, Christian, Palacı́n, Manuel, Testar, Xavier

“…Semicarbazide-sensitive amine oxidase (SSAO) is very abundant at the plasma membrane in adipocytes. The combination of SSAO substrates and low concentrations…”
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Rab11 is associated with GLUT4-containing vesicles and redistributes in response to insulin by Kessler, A, Tomas, E, Immler, D, Meyer, H E, Zorzano, A, Eckel, J

“…To identify a GTPase of 24,000 M(r) which we recently found to co-localize with GLUT4 in cardiac muscle. A 24,000 M(r)-GTP-binding fraction was purified from…”
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Identification of novel GH-regulated genes in C2C12 cells by Resmini, E, Morte, B, Sorianello, E, Gallardo, E, de Luna, N, Illa, I, Zorzano, A, Bernal, J, Webb, S M

“…Growth hormone (GH) is the main regulator of longitudinal growth before puberty, and treatment with human recombinant (rh) GH can increase muscle strength…”
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Amine oxidase substrates mimic several of the insulin effects on adipocyte differentiation in 3T3 F442A cells by Fontana, E, Boucher, J, Marti, L, Lizcano, J M, Testar, X, Zorzano, A, Carpéné, C

“…We have previously reported that substrates of monoamine oxidase (MAO) and semicarbazide-sensitive amine oxidase (SSAO) exert short-term insulin-like effects…”
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Substrates of semicarbazide-sensitive amine oxidase co-operate with vanadate to stimulate tyrosine phosphorylation of insulin-receptor-substrate proteins, phosphoinositide 3-kinase activity and GLUT4 translocation in adipose cells by Enrique-Tarancón, G, Castan, I, Morin, N, Marti, L, Abella, A, Camps, M, Casamitjana, R, Palacín, M, Testar, X, Degerman, E, Carpéné, C, Zorzano, A

“…It has been shown that the combination of benzylamine or tyramine and low concentrations of vanadate markedly stimulates glucose transport in rat adipocytes by…”
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The amino acid transport system b(o,+) and cystinuria by Palacin, M, Fernández, E, Chillarón, J, Zorzano, A

“…Amino acid transport in mammalian plasma membranes is mediated by a multiplicity of amino acid transport systems. Some of them (systems L, y+ L, x(c)- and…”
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Insulin-regulated Glucose Uptake in Rat Adipocytes Is Mediated by Two Transporter Isoforms Present in at Least Two Vesicle Populations by Zorzano, A, Wilkinson, W, Kotliar, N, Thoidis, G, Wadzinkski, B E, Ruoho, A E, Pilch, P F

“…We have recently described a monoclonal antibody (1F8) that recognizes a form of glucose transporter unique to fat and muscle (James, D. E., Brown, R.,…”
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Intracellular signals involved in the effects of insulin-like growth factors and neuregulins on myofibre formation by Zorzano, Antonio, Kaliman, Perla, Gumà, Anna, Palacı́n, Manuel

“…A number of extracellular factors are involved in the embryonic development of skeletal muscle and the muscle regeneration that is triggered in response to…”
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