Search Results - "ZONGHUI HU"

A randomized controlled trial of rituximab following failure of antiviral therapy for hepatitis C virus-associated cryoglobulinemic vasculitis by Sneller, Michael C., Hu, Zonghui, Langford, Carol A.

“…Objective To perform a randomized controlled trial of rituximab in patients with hepatitis C virus (HCV)–associated mixed cryoglobulinemic vasculitis. Methods…”
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A multiclade env–gag VLP mRNA vaccine elicits tier-2 HIV-1-neutralizing antibodies and reduces the risk of heterologous SHIV infection in macaques by Zhang, Peng, Narayanan, Elisabeth, Liu, Qingbo, Tsybovsky, Yaroslav, Boswell, Kristin, Ding, Shilei, Hu, Zonghui, Follmann, Dean, Lin, Yin, Miao, Huiyi, Schmeisser, Hana, Rogers, Denise, Falcone, Samantha, Elbashir, Sayda M., Presnyak, Vladimir, Bahl, Kapil, Prabhakaran, Madhu, Chen, Xuejun, Sarfo, Edward K., Ambrozak, David R., Gautam, Rajeev, Martin, Malcom A., Swerczek, Joanna, Herbert, Richard, Weiss, Deborah, Misamore, Johnathan, Ciaramella, Giuseppe, Himansu, Sunny, Stewart-Jones, Guillaume, McDermott, Adrian, Koup, Richard A., Mascola, John R., Finzi, Andrés, Carfi, Andrea, Fauci, Anthony S., Lusso, Paolo

“…The development of a protective vaccine remains a top priority for the control of the HIV/AIDS pandemic. Here, we show that a messenger RNA (mRNA) vaccine…”
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Chimpanzee Adenovirus Vector Ebola Vaccine by Ledgerwood, Julie E, DeZure, Adam D, Stanley, Daphne A, Coates, Emily E, Novik, Laura, Enama, Mary E, Berkowitz, Nina M, Hu, Zonghui, Joshi, Gyan, Ploquin, Aurélie, Sitar, Sandra, Gordon, Ingelise J, Plummer, Sarah A, Holman, LaSonji A, Hendel, Cynthia S, Yamshchikov, Galina, Roman, Francois, Nicosia, Alfredo, Colloca, Stefano, Cortese, Riccardo, Bailer, Robert T, Schwartz, Richard M, Roederer, Mario, Mascola, John R, Koup, Richard A, Sullivan, Nancy J, Graham, Barney S

“…This update of a preliminary report from November 2014 presents safety, immunogenicity, and long-term durability data from a trial of an Ebola vaccine in…”
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Electropermanent magnet blank holder technique in sheet metal deep drawing by Qin, Siji, Zhang, Hongsheng, Mao, Yaoben, Yang, Le, Li, Xianbin, Hu, Zonghui, Cheng, Xiao

“…A novel blank holder technique based on electropermanent magnet (EPM) technology is proposed, in which independent loading of blank holding force (BHF) can be…”
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DNA priming and influenza vaccine immunogenicity: two phase 1 open label randomised clinical trials by Ledgerwood, Julie E, DO, Wei, Chih-Jen, PhD, Hu, Zonghui, PhD, Gordon, Ingelise J, RN, Enama, Mary E, PA-C, Hendel, Cynthia S, CRNP, McTamney, Patrick M, PhD, Pearce, Melissa B, PhD, Yassine, Hadi M, PhD, Boyington, Jeffrey C, PhD, Bailer, Robert, PhD, Tumpey, Terrence M, PhD, Koup, Richard A, MD, Mascola, John R, MD, Nabel, Gary J, MD, Graham, Barney S, MD

“…Summary Background Because the general population is largely naive to H5N1 influenza, antibodies generated to H5 allow analysis of novel influenza vaccines…”
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Prime-Boost Interval Matters: A Randomized Phase 1 Study to Identify the Minimum Interval Necessary to Observe the H5 DNA Influenza Vaccine Priming Effect by Ledgerwood, Julie E., Zephir, Kathryn, Hu, Zonghui, Wei, Chih-Jen, Chang, LeeJah, Enama, Mary E., Hendel, Cynthia S., Sitar, Sandra, Bailer, Robert T., Koup, Richard A., Mascola, John R., Nabel, Gary J., Graham, Barney S.

“…Background. H5 DNA priming was previously shown to improve the antibody response to influenza A(H5N1) monovalent inactivated vaccine (MIV) among individuals…”
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Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial by Kibuuka, Hannah, MMed, Berkowitz, Nina M, MPH, Millard, Monica, MPH, Enama, Mary E, MA, Tindikahwa, Allan, MPH, Sekiziyivu, Arthur B, MSc, Costner, Pamela, BSN, Sitar, Sandra, MS, Glover, Deline, BS, Hu, Zonghui, PhD, Joshi, Gyan, MPH, Stanley, Daphne, MS, Kunchai, Meghan, MPH, Eller, Leigh Anne, PhD, Bailer, Robert T, PhD, Koup, Richard A, MD, Nabel, Gary J, MD, Mascola, John R, MD, Sullivan, Nancy J, PhD, Graham, Barney S, MD, Roederer, Mario, PhD, Michael, Nelson L, MD, Robb, Merlin L, MD, Ledgerwood, Julie E, Dr

“…Summary Background Ebola virus and Marburg virus cause serious disease outbreaks with high case fatality rates. We aimed to assess the safety and…”
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Interleukin-15 (IL-15) Strongly Correlates with Increasing HIV-1 Viremia and Markers of Inflammation by Swaminathan, Sanjay, Qiu, Ju, Rupert, Adam W, Hu, Zonghui, Higgins, Jeanette, Dewar, Robin L, Stevens, Randy, Rehm, Catherine A, Metcalf, Julia A, Sherman, Brad T, Baseler, Michael W, Lane, H Clifford, Imamichi, Tomozumi

“…IL-15 has been postulated to play an important role in HIV-1 infection, yet there are conflicting reports regarding its expression levels in these patients. We…”
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Winter Green Manure Decreases Subsoil Nitrate Accumulation and Increases N Use Efficiencies of Maize Production in North China Plain by Hu, Zonghui, Zhao, Qiu, Zhang, Xinjian, Ning, Xiaoguang, Liang, Hao, Cao, Weidong

“…Planting a deep-rooted green manure (GM) (more than 1.0 m depth) greatly improves soil fertility and reduces the loss of nutrients. However, few studies have…”
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Safety and tolerability of chikungunya virus-like particle vaccine in healthy adults: a phase 1 dose-escalation trial by Chang, Lee-Jah, MD, Dowd, Kimberly A, PhD, Mendoza, Floreliz H, RN, Saunders, Jamie G, BSN, Sitar, Sandra, MSc, Plummer, Sarah H, NP, Yamshchikov, Galina, MSc, Sarwar, Uzma N, MD, Hu, Zonghui, PhD, Enama, Mary E, PA-C, Bailer, Robert T, PhD, Koup, Richard A, MD, Schwartz, Richard M, PhD, Akahata, Wataru, PhD, Nabel, Gary J, MD, Mascola, John R, MD, Pierson, Theodore C, PhD, Graham, Barney S, MD, Ledgerwood, Julie E, Dr

“…Summary Background Chikungunya virus—a mosquito-borne alphavirus—is endemic in Africa and south and southeast Asia and has recently emerged in the Caribbean…”
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HIV infection-associated immune activation occurs by two distinct pathways that differentially affect CD4 and CD8 T cells by Catalfamo, Marta, Di Mascio, Michele, Hu, Zonghui, Srinivasula, Sharat, Thaker, Vishakha, Adelsberger, Joseph, Rupert, Adam, Baseler, Michael, Tagaya, Yutaka, Roby, Gregg, Rehm, Catherine, Follmann, Dean, Lane, H. Clifford

“…HIV infection is characterized by a brisk immune activation that plays an important role in the CD4 depletion and immune dysfunction of patients with AIDS. The…”
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Enhanced Effector Function of CD8+T Cells From Healthy Controls and HIV-Infected Patients Occurs Through Thrombin Activation of Protease-Activated Receptor 1 by Hurley, Amanda, Smith, Mindy, Karpova, Tatiana, Hasley, Rebecca B., Belkina, Natalya, Shaw, Stephen, Balenga, Nariman, Druey, Kirk M., Nickel, Erin, Packard, Beverly, Imamichi, Hiromi, Hu, Zonghui, Follmann, Dean, McNally, James, Higgins, Jeanette, Sneller, Michael, Lane, H. Clifford, Catalfamo, Marta

“…Disruption of vascular integrity by trauma and other tissue insults leads to inflammation and activation of the coagulation cascade. The serine protease…”
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Decreases in IL-7 levels during antiretroviral treatment of HIV infection suggest a primary mechanism of receptor-mediated clearance by Hodge, Jessica N., Srinivasula, Sharat, Hu, Zonghui, Read, Sarah W., Porter, Brian O., Kim, Insook, Mican, JoAnn M., Paik, Chang, DeGrange, Paula, Di Mascio, Michele, Sereti, Irini

“…IL-7 is essential for T-cell homeostasis. Elevated serum IL-7 levels in lymphopenic states, including HIV infection, are thought to be due to increased…”
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Overcoming Allelic Specificity by Immunization with Five Allelic Forms of Plasmodium falciparum Apical Membrane Antigen 1 by Miura, Kazutoyo, Herrera, Raul, Diouf, Ababacar, Zhou, Hong, Mu, Jianbing, Hu, Zonghui, MacDonald, Nicholas J, Reiter, Karine, Nguyen, Vu, Shimp, Jr, Richard L, Singh, Kavita, Narum, David L, Long, Carole A, Miller, Louis H

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Impact of lamivudine on HIV and hepatitis B virus-related outcomes in HIV/hepatitis B virus individuals in a randomized clinical trial of antiretroviral therapy in southern Africa by MATTHEWS, Gail V, MANZINI, Prince, EMERY, Sean, ZONGHUI HU, KHABO, Paul, MAJA, Patrick, MATCHABA, Gugu, SANGWENI, Phumele, METCALF, Julie, POOL, Nicholaas, ORSEGA, Susan

“…To examine HIV and hepatitis B virus (HBV)-related outcomes in HIV/HBV-coinfected participants in the PHIDISA II study by use of HBV-active vs. non-HBV-active…”
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Chronic exposure to type-I IFN under lymphopenic conditions alters CD4 T cell homeostasis by Le Saout, Cecile, Hasley, Rebecca B, Imamichi, Hiromi, Tcheung, Lueng, Hu, Zonghui, Luckey, Megan A, Park, Jung-Hyun, Durum, Scott K, Smith, Mindy, Rupert, Adam W, Sneller, Michael C, Lane, H Clifford, Catalfamo, Marta

“…HIV infection and the associated chronic immune activation alter T cell homeostasis leading to CD4 T cell depletion and CD8 T cell expansion. The mechanisms…”
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Assessing conditional causal effect via characteristic score by Hu, Zonghui

“…Observational studies usually include participants representing the wide heterogeneous population. The conditional causal effect, treatment effect conditional…”
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An avian influenza H7 DNA priming vaccine is safe and immunogenic in a randomized phase I clinical trial by DeZure, Adam D., Coates, Emily E., Hu, Zonghui, Yamshchikov, Galina V., Zephir, Kathryn L., Enama, Mary E., Plummer, Sarah H., Gordon, Ingelise J., Kaltovich, Florence, Andrews, Sarah, McDermott, Adrian, Crank, Michelle C., Koup, Richard A, Schwartz, Richard M., Bailer, Robert T., Sun, Xiangjie, Mascola, John R., Tumpey, Terrence M., Graham, Barney S., Ledgerwood, Julie E.

“…A novel avian influenza subtype, A/H7N9, emerged in 2013 and represents a public health threat with pandemic potential. We have previously shown that DNA…”
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Serum tryptase levels in atopic and nonatopic children by Komarow, Hirsh D., MD, Hu, Zonghui, PhD, Brittain, Erica, PhD, Uzzaman, Ashraf, MD, Gaskins, Donna, RN, Metcalfe, Dean D., MD

“…The patients were categorized as either nonatopic (n = 44) or atopic (n = 153), according to the presence of allergic symptoms and a tendency to produce IgE…”
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Plasma interleukin-27 (IL-27) levels are not modulated in patients with chronic HIV-1 infection by Swaminathan, Sanjay, Hu, Zonghui, Rupert, Adam W, Higgins, Jeanette M, Dewar, Robin L, Stevens, Randy, Chen, Qian, Rehm, Catherine A, Metcalf, Julia A, Baseler, Michael W, Lane, H Clifford, Imamichi, Tomozumi

“…IL-27 is an immunomodulatory cytokine with potent anti-HIV properties in PBMCs, CD4+ T cells, macrophages and immature dendritic cells. Previous smaller…”
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