Search Results - "ZOMPI, Simona"

Animal models of dengue virus infection by Zompi, Simona, Harris, Eva

“…The development of animal models of dengue virus (DENV) infection and disease has been challenging, as epidemic DENV does not naturally infect non-human…”
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Original antigenic sin in dengue revisited by Zompi, Simona, Harris, Eva

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Detection of microbial cell-free DNA in maternal and umbilical cord plasma in patients with chorioamnionitis using next generation sequencing by Witt, Russell G, Blair, Lily, Frascoli, Michela, Rosen, Michael J, Nguyen, Quoc-Hung, Bercovici, Sivan, Zompi, Simona, Romero, Roberto, Mackenzie, Tippi C

“…Chorioamnionitis has been linked to spontaneous preterm labor and complications such as neonatal sepsis. We hypothesized that microbial cell-free (cf) DNA…”
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Correlation between dengue-specific neutralizing antibodies and serum avidity in primary and secondary dengue virus 3 natural infections in humans by Puschnik, Andreas, Lau, Louis, Cromwell, Elizabeth A, Balmaseda, Angel, Zompi, Simona, Harris, Eva

“…Although heterotypic secondary infection with dengue virus (DENV) is associated with severe disease, the majority of secondary infections are mild or…”
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Dominant cross-reactive B cell response during secondary acute dengue virus infection in humans by Zompi, Simona, Montoya, Magelda, Pohl, Marie O, Balmaseda, Angel, Harris, Eva

“…The four serotypes of dengue virus (DENV) cause dengue fever (DF) and dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS). Severe disease has been…”
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A Mouse Model for Studying Dengue Virus Pathogenesis and Immune Response by Williams, Katherine L., Zompi, Simona, Beatty, P. Robert, Harris, Eva

“…A small animal model for studying dengue disease is of critical importance to furthering many areas of dengue research, including host immunity, disease…”
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Phospholipase C-γ2 is essential for NK cell cytotoxicity and innate immunity to malignant and virally infected cells by Caraux, Anouk, Kim, Nayoung, Bell, Sarah E., Zompi, Simona, Ranson, Thomas, Lesjean-Pottier, Sarah, Garcia-Ojeda, Marcos E., Turner, Martin, Colucci, Francesco

“…Phospholipase C-γ2 (PLC-γ2) is a key component of signal transduction in leukocytes. In natural killer (NK) cells, PLC-γ2 is pivotal for cellular cytotoxicity;…”
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NKG2D triggers cytotoxicity in mouse NK cells lacking DAP12 or Syk family kinases by Tybulewicz, Victor L J, Di Santo, James P, Hamerman, Jessica A, Schweighoffer, Edina, Ogasawara, Kouetsu, Lanier, Lewis L, Zompi, Simona, Colucci, Francesco

“…In activated mouse natural killer (NK) cells, the NKG2D receptor associates with two intracellular adaptors, DAP10 and DAP12, which trigger phosphatidyl…”
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Clonality analysis of alveolar B lymphocytes contributes to the diagnostic strategy in clinical suspicion of pulmonary lymphoma by Zompi, Simona, Couderc, Louis-Jean, Cadranel, Jacques, Antoine, Martine, Epardeau, Bernard, Fleury-Feith, Jocelyne, Popa, Natalia, Santoli, François, Farcet, Jean-Pierre, Delfau-Larue, Marie-Hélène

“…The diagnostic procedure of chronic pulmonary opacities may envisage the search for non-Hodgkin lymphoma (NHL). Previous retrospective studies have shown that…”
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The absence of Grb2-associated binder 2 (Gab2) does not disrupt NK cell development and functions by Zompi, Simona, Gu, Hahiua, Colucci, Francesco

“…Scaffolding molecules bind simultaneously and link together various components of signal‐transduction pathways. Grb2‐associated binder 2 (Gab2) is a…”
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Role of Gab proteins in phosphatidylinositol 3-kinase activation by thrombopoietin (Tpo) by BOUSCARY, Didier, LECOQ-LAFON, Carinne, LACOMBE, Catherine, CHRETIEN, Stany, ZOMPI, Simona, FICHELSON, Serge, MULLER, Odile, PORTEU, Francoise, DUSANTER-FOURT, Isabelle, GISSELBRECHT, Sylvie, MAYEUX, Patrick

“…In this study, we show that upon thrombopoietin (Tpo) stimulation the two adapter proteins Gab1 and Gab2 are strongly tyrosine phosphorylated and associated…”
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Plasma Microbial Cell-free DNA Next-generation Sequencing in the Diagnosis and Management of Febrile Neutropenia by Benamu, Esther, Gajurel, Kiran, Anderson, Jill N, Lieb, Tullia, Gomez, Carlos A, Seng, Hon, Aquino, Romielle, Hollemon, Desiree, Hong, David K, Blauwkamp, Timothy A, Kertesz, Mickey, Blair, Lily, Bollyky, Paul L, Medeiros, Bruno C, Coutre, Steven, Zompi, Simona, Montoya, Jose G, Deresinski, Stan

“…Abstract Background Standard testing fails to identify a pathogen in most patients with febrile neutropenia (FN). We evaluated the ability of the Karius…”
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Protection from secondary dengue virus infection in a mouse model reveals the role of serotype cross-reactive B and T cells by Zompi, Simona, Santich, Brian H, Beatty, P Robert, Harris, Eva

“…The four dengue virus (DENV) serotypes cause dengue fever and dengue hemorrhagic fever/dengue shock syndrome. Although severe disease has been associated with…”
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Convergent Antibody Signatures in Human Dengue by Parameswaran, Poornima, Liu, Yi, Roskin, Krishna M., Jackson, Katherine K.L., Dixit, Vaishali P., Lee, Ji-Yeun, Artiles, Karen L., Zompi, Simona, Vargas, Maria José, Simen, Birgitte B., Hanczaruk, Bozena, McGowan, Kim R., Tariq, Muhammad A., Pourmand, Nader, Koller, Daphne, Balmaseda, Angel, Boyd, Scott D., Harris, Eva, Fire, Andrew Z.

“…Dengue is the most prevalent mosquito-borne viral disease in humans, and the lack of early prognostics, vaccines, and therapeutics contributes to immense…”
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Whole Genome Sequencing of Dengue Virus Serotype 2 from Two Clinical Isolates and Serological Profile of Dengue in the 2015-2016 Nepal Outbreak by Manandhar, Krishna Das, McCauley, Melanie, Gupta, Birendra Prasad, Kurmi, Roshan, Adhikari, Anurag, Nguyen, Anh-Viet, Elong Ngono, Annie, Zompi, Simona, Sessions, October M, Shresta, Sujan

“…Dengue virus (DENV) is the cause of one of the most prevalent neglected tropical diseases, and up to half of the world's population is at risk for infection…”
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Plasma Cell-Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients by Fung, Monica, Zompi, Simona, Seng, Hon, Hollemon, Desiree, Parham, Adama, Hong, David K, Bercovici, Sivan, Dolan, Estelle, Lien, Kathy, Teraoka, Justin, Logan, Aaron C, Chin-Hong, Peter

“…Allogeneic hematopoietic stem cell transplant patients are at risk for common and atypical infections. Superior diagnostics can decrease infection-related…”
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Protective immune responses to dengue virus infection and vaccines: perspectives from the field to the bench by Halstead, Scott B, Zompi, Simona

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Protection from Secondary Dengue Virus Infection in a Mouse Model Reveals the Role of Serotype Cross-reactive B and T cells1,2 by Zompi, Simona, Santich, Brian H., Beatty, P. Robert, Harris, Eva

“…The four dengue virus (DENV) serotypes cause dengue fever (DF) and dengue hemorrhagic fever/dengue shock syndrome. Although severe disease has been associated…”
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Dengue virus nonstructural protein 1 vaccine protects against lethal challenge in interferon α/β receptor-deficient mice (P6348) by Beatty, P Robert, Orozco, Susana, Killingbeck, Sarah, Zompi, Simona, Harris, Eva

“…Dengue virus (DENV) is a flavivirus that infects 100 million people and causes severe disease in ~500,000 people annually. DENV nonstructural protein 1 (NS1)…”
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Role of acute B cell response in dengue disease severity and long-term immunity (67.19) by Montoya, Magelda, Simona, Zompi, Pohl, Marie, Balmaseda, Angel, Harris, Eva

“…The four serotypes of dengue virus (DENV) cause dengue fever (DF) and dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS), the most prevalent…”
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