Search Results - "ZIYI LIM"

Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value by Smith, Alexander E., Mohamedali, Azim M., Kulasekararaj, Austin, Lim, ZiYi, Gäken, Joop, Lea, Nicholas C., Przychodzen, Bartlomiej, Mian, Syed A., Nasser, Erick E., Shooter, Claire, Westwood, Nigel B., Strupp, Corinna, Gattermann, Norbert, Maciejewski, Jaroslaw P., Germing, Ulrich, Mufti, Ghulam J.

“…Mutations in the TET2 gene are frequent in myeloid disease, although their biologic and prognostic significance remains unclear. We analyzed 355 patients with…”
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Allogeneic Hematopoietic Stem-Cell Transplantation for Patients 50 Years or Older With Myelodysplastic Syndromes or Secondary Acute Myeloid Leukemia by ZIYI LIM, BRAND, Ronald, RUUTU, Tapani, BOOGAERTS, Marc, FALDA, Michele, JOUET, Jean-Pierre, NIEDERWIESER, Dietger, KROGER, Nicolaus, MUFTI, Ghulam J, DE WITTE, Theo M, MARTINO, Rodrigo, VAN BIEZEN, Anja, FINKE, Jürgen, BACIGALUPO, Andrea, BEELEN, Dietrich, DEVERGIE, Agnes, ALESSANDRINO, Emilio, WILLEMZE, Roel

“…This study was performed to examine the characteristics of transplant activity for patients with myelodysplastic syndromes (MDS) older than 50 years within the…”
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Imbalance of effector and regulatory CD4 T cells is associated with graft-versus-host disease after hematopoietic stem cell transplantation using a reduced intensity conditioning regimen and alemtuzumab by Matthews, Katie, Lim, ZiYi, Afzali, Behdad, Pearce, Laurence, Abdallah, Atiyeh, Kordasti, Shahram, Pagliuca, Antonio, Lombardi, Giovanna, Madrigal, J. Alejandro, Mufti, Ghulam J, Barber, Linda D

“…1 The Anthony Nolan Research Institute, Royal Free Hospital, London; 2 Department of Haematological Medicine, King’s College London Denmark Hill Campus, London…”
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Diffuse large B-cell lymphoma developing following treatment of Waldenstrom's macroglobulinaemia: Spontaneous resolution upon cessation of fludarabine by Lim, Ziyi, Cassells, Rachael, Giles, Andrew, Cheow, Heok Keong, Mir, Naheed

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Disease Risk Index (DRI) and Conditioning Regimen Based Risk Stratification of Outcome Among Adults with Acute Myeloid Leukemia Receiving Allogeneic Hematopoietic Cell Transplantation by Yip, Alexander, MD, Tai, Bee Choo, Linn, Yeh Ching, MD, Tan, Lip Kun, MD, Poon, Michelle Limei, MD, Lim, Ziyi, MD, Tan, Belinda, Lim, Yelly, Soh, Teck-Guan, MSc, Del Rosario, Davanaliz R, Hwang, William Y.K., FRCP, FAMS, MMed, MRCP, MBBS, Koh, Liang Piu, MD

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IL‐17‐producing CD4+ T cells, pro‐inflammatory cytokines and apoptosis are increased in low risk myelodysplastic syndrome by Kordasti, Shahram Y., Afzali, Behdad, Lim, Ziyi, Ingram, Wendy, Hayden, Janet, Barber, Linda, Matthews, Katie, Chelliah, Rajani, Guinn, Barbara, Lombardi, Giovanna, Farzaneh, Farzin, Mufti, Ghulam J.

“…Summary Immunological responses are increasingly recognised as being important in the initiation and progression of myelodysplastic syndrome (MDS). Indeed,…”
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Alemtuzumab with fludarabine and cyclophosphamide reduces chronic graft-versus-host disease after allogeneic stem cell transplantation for acquired aplastic anemia by Marsh, Judith C., Gupta, Vikas, Lim, ZiYi, Ho, Aloysius Y., Ireland, Robin M., Hayden, Janet, Potter, Victoria, Koh, Mickey B., Islam, M. Serajul, Russell, Nigel, Marks, David I., Mufti, Ghulam J., Pagliuca, Antonio

“…We evaluated a novel alemtuzumab-based conditioning regimen in HSCT for acquired severe aplastic anemia (SAA). In a multicenter retrospective study, 50…”
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HLA-Haploidentical Hematopoietic Cell Transplantation after TCR-Αβ and CD45RA+ Depletion Following Reduced Intensity Conditioning in Adults and Children with Hematological Malignancies- Two-Year Follow-up of Multicenter Study in Singapore by Poon, Li Mei, Linn, Yeh Ching, Tan, Poh Lin, LIM, Ziyi, Vellayappan, Balamurugan, Bhattacharyya, Rajat, Tan, Ah Moy, Tan, Lip Kun, Soh, Teck Guan, Diong, Colin Phipps, Leung, Wing H., Koh, Liang Piu

“…Background: Haploidentical hematopoietic cell transplantation (HCT) provides an alternative option for patients without HLA-matched donor. GVHD, engraftment…”
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Double Unit Umbilical Cord Blood Transplant for Adults with Acute Leukemia and Myelodysplastic Syndrome Results in Comparable Outcome As Matched Sibling or Unrelated Donor Transplant Only after Myeloablative Conditioning but Not Reduced Intensity Conditio by Poon, Michelle Limei, MD, Linn, Yeh Ching, MD, Lim, Ziyi, MD, Ho, Aloysius, MD, Tan, Lip Kun, MD, Soh, Teck Guan, Master Degree, Heng, Kk, Tan, Belinda, Yelly, Lee, Jing Jing, Ng, Heng Joo, MD, Hwang, William Y.K., MD, Koh, Liang Piu, MD

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Hepatitis B virus infection: pathogenesis, reactivation and management in hematopoietic stem cell transplant recipients by Moses, Samuel E, Lim, ZiYi, Zuckerman, Mark A

“…Hepatitis B virus (HBV) is a partially double stranded DNA virus that can integrate into host cell chromosomes as covalently closed circular DNA forms. HBV…”
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Successful pregnancies involving men with chronic myeloid leukaemia on imatinib therapy by Ramasamy, Karthik, Hayden, Janet, Lim, ZiYi, Mufti, Ghulam J., Ho, Aloysius Y. L.

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Allogeneic Stem Cell Transplantation for Accelerated/Blastic Phase Philadelphia-Chromosome Negative MPN by Khan, Anjum Bashir, McLornan, Donal, Jethava, Yogesh, Raj, Kavita, Potter, Victoria T, de Lavallade, Hugues, Kazmi, Majid A, Lim, ZiYi, Marsh, Judith C.W., Atwal, Sangeeta, Noriega, Victor, Harrison, Claire N, Pagliuca, Antonio, Mufti, Ghulam J.

“…Abstract 4532 Myeloproliferative Neoplasm (MPN)-Leukaemic Transformation (LT) uniformly carries a dismal prognosis. Effective therapy for such patients are…”
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Rapid recovery of lymphocyte subsets is not associated with protection from relapse of myelodysplastic syndromes and acute myeloid leukaemia after haematopoietic stem cell transplantation using a reduced intensity conditioning regimen and alemtuzumab by Matthews, Katie, Lim, ZiYi, Pearce, Laurence, Pagliuca, Antonio, Alejandro Madrigal, J., Mufti, Ghulam J., Barber, Linda D.

“…Summary Graft‐versus‐leukaemia (GvL) and graft‐versus‐host disease (GvHD) are both caused by alloreactive lymphocytes. We previously reported that GvHD…”
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National, Retrospective, Multi-Centre Comparison of Alemtuzumab- Versus ATG-Based Conditioning Regimens in Hematopoietic Stem Cell Transplantation for Aplastic Anemia: A Study From the British Society for Blood and Marrow Transplantation (BSBMT) (CTCR 09-03) by Marsh, Judith C.W., Pearce, Rachel M, Koh, Mickey B, Tang, Daniel, Lim, ZiYi, Pagliuca, Antonio, Mufti, Ghulam J., Snowden, John, Vora, Ajay J, Gibson, Brenda, Gilleece, Maria H, Lee, Julia, Kirkland, Keiren, Cook, Gordon

“…Abstract 52▪▪This icon denotes a clinically relevant abstract The ideal conditioning regimen for HSCT in AA is one that achieves engraftment, absence of GVHD…”
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Pre-Emptive Donor Lymphocyte Infusions (DLI) Lead to High Cure Rates in T-Cell Depleted Allogeneic Haemopoietic Stem Cell Transplants for MDS/AML by Krishnamurthy, Pramila, Potter, Victoria T, Lim, ZiYi, Kulasekararaj, Austin G, Ho, Aloysius Y, Marsh, Judith C.W., Ireland, Robin M., Devereux, Stephen, Pagliuca, Antonio, Mufti, Ghulam J.

“…Abstract 660 Relapse is a major cause of treatment failure following allogeneic haemopoietic stem cell transplants (HSCT). Donor lymphocyte infusions may be…”
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Long-Term Outcomes of Reduced Intensity Conditioning Haematopoietic Stem Cell Transplantation (RIC-HSCT) for AML with Myelodysplasia-Related Changes by Potter, Victoria T, Krishnamurthy, Pramila, Lim, ZiYi, Tindell, Victoria J, Devereux, Stephen, Marcus, Robert E., Ireland, Robin M., Marsh, Judith C.W., Pagliuca, Antonio, Mufti, Ghulam J.

“…Abstract 3079 Patients with acute myeloid leukaemia secondary to myelodysplastic syndromes (sAML) are often considered to have inferior outcomes to patients…”
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Telomere Length In MDS Patients Bone Marrow Is Highly Correlated with Complex Cytogenetics, IPSS Risk Groups and Transfusion Dependency by Jiang, Jie, Kulasekararaj, Austin G, Krishnamurthy, Pramila, Smith, Alexander E, Mian, Syed A, Gandhi, Shreyans, Hayden, Janet, Gaken, Joop, Elebute, Modupe, Ireland, Robin M., Lim, ZiYi, Marsh, Judith C.W., Mufti, Ghulam J.

“…Abstract 3826 Myelodysplastic syndromes (MDS) are hematopoietic stem cell disorders characterized by ineffective haematopoiesis. Age, gender, mutagen exposure…”
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TP53 Mutations Are Restricted Predominantly to 5q- Syndrome and Myelodysplastic Syndrome Patients with Complex Cytogenetics, and Correlate with Adverse Prognosis by Kulasekararaj, Austin G, Smith, Alexander E, Mian, Syed A, Krishnamurthy, Pramila, Mohamedali, Azim M, Lea, Nicholas C, Hayden, Janet, Gaken, Joop, Elebute, Modupe, Ireland, Robin M., Pomplun, Sabine, Lim, ZiYi, Marsh, Judith C.W., Mufti, Ghulam J.

“…Abstract 792 Myelodysplastic syndromes are clinically and molecularly heterogeneous group of disorders with variable prognosis and propensity to leukaemic…”
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A Decade of Reduced-Intensity Conditioned Allogeneic Haematopoietic Stem Cell Transplantation for Myelodysplastic Syndromes Following Conditioning with Fludarabine, Busulphan and Alemtuzumab by Ho, Aloysius YL, Krishnamurthy, Pramila, Lim, ZiYi, Kenyon, Michelle, Mijovic, Aleksander, Devereux, Stephen, Pagliuca, Antonio, Mufti, Ghulam J

“…Abstract 2266 Poster Board II-243 Reduced-intensity conditioning haematopoietic stem cell transplantation has dramatically improved the accessibility and…”
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Alemtuzumab Used with Fludarabine and Cyclophosphamide (FCC) for Stem Cell Transplantation in Acquired Aplastic Anemia Is Associated with a Low Risk of Graft Versus Host Disease and Viral Infections and with Sustained Engraftment by Marsh, Judith C W, Gupta, Vikas, Lim, ZiYi, Marks, David, Gordon-Smith, Edward C., Mufti, Ghulam J

“…Abstract 1084 Poster Board I-106 Graft rejection and chronic GVHD remain major obstacles to successful outcome after stem cell transplantation (SCT) for…”
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