Search Results - "ZITTERBART, Karel"

Uniformity under in vitro conditions: Changes in the phenotype of cancer cell lines derived from different medulloblastoma subgroups by Chlapek, Petr, Zitterbart, Karel, Kren, Leos, Filipova, Lenka, Sterba, Jaroslav, Veselska, Renata

“…Medulloblastoma comprises four main subgroups (WNT, SHH, Group 3 and Group 4) originally defined by transcriptional profiling. In primary medulloblastoma…”
Get full text

Nestin expression in osteosarcomas and derivation of nestin/CD133 positive osteosarcoma cell lines by Veselska, Renata, Hermanova, Marketa, Loja, Tomas, Chlapek, Petr, Zambo, Iva, Vesely, Karel, Zitterbart, Karel, Sterba, Jaroslav

“…Nestin was originally identified as a class VI intermediate filament protein that is expressed in stem cells and progenitor cells in the mammalian CNS during…”
Get full text

Enhancement of ATRA-induced differentiation of neuroblastoma cells with LOX/COX inhibitors: an expression profiling study by Chlapek, Petr, Redova, Martina, Zitterbart, Karel, Hermanova, Marketa, Sterba, Jaroslav, Veselska, Renata

“…We performed expression profiling of two neuroblastoma cell lines, SK-N-BE(2) and SH-SY5Y, after combined treatment with all-trans retinoic acid (ATRA) and…”
Get full text

CD133 expression and identification of CD133/nestin positive cells in rhabdomyosarcomas and rhabdomyosarcoma cell lines by Sana, Jiri, Zambo, Iva, Skoda, Jan, Neradil, Jakub, Chlapek, Petr, Hermanova, Marketa, Mudry, Peter, Vasikova, Alzbeta, Zitterbart, Karel, Hampl, Ales, Sterba, Jaroslav, Veselska, Renata

“…Co-expression of CD133, cell surface glycoprotein, and nestin, an intermediate filament protein, was determined to be a marker of neural stem cells and of…”
Get full text

CD133 expression and identification of CD133/nestin positive cells in rhabdomyosarcomas and rhabdomyosarcoma cell lines by Sana, Jiri, Zambo, Iva, Skoda, Jan, Neradil, Jakub, Chlapek, Petr, Hermanova, Marketa, Mudry, Peter, Vasikova, Alzbeta, Zitterbart, Karel, Hampl, Ales, Sterba, Jaroslav, Veselska, Renata

“…BACKGROUNDCo-expression of CD133, cell surface glycoprotein, and nestin, an intermediate filament protein, was determined to be a marker of neural stem cells…”
Get full text

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma by Northcott, Paul A., Lee, Catherine, Zichner, Thomas, Stütz, Adrian M., Erkek, Serap, Kawauchi, Daisuke, Shih, David J. H., Hovestadt, Volker, Zapatka, Marc, Sturm, Dominik, Jones, David T. W., Kool, Marcel, Remke, Marc, Cavalli, Florence M. G., Zuyderduyn, Scott, Bader, Gary D., VandenBerg, Scott, Esparza, Lourdes Adriana, Ryzhova, Marina, Wang, Wei, Wittmann, Andrea, Stark, Sebastian, Sieber, Laura, Seker-Cin, Huriye, Linke, Linda, Kratochwil, Fabian, Jäger, Natalie, Buchhalter, Ivo, Imbusch, Charles D., Zipprich, Gideon, Raeder, Benjamin, Schmidt, Sabine, Diessl, Nicolle, Wolf, Stephan, Wiemann, Stefan, Brors, Benedikt, Lawerenz, Chris, Eils, Jürgen, Warnatz, Hans-Jörg, Risch, Thomas, Yaspo, Marie-Laure, Weber, Ursula D., Bartholomae, Cynthia C., von Kalle, Christof, Turányi, Eszter, Hauser, Peter, Sanden, Emma, Darabi, Anna, Siesjö, Peter, Sterba, Jaroslav, Zitterbart, Karel, Sumerauer, David, van Sluis, Peter, Versteeg, Rogier, Volckmann, Richard, Koster, Jan, Schuhmann, Martin U., Ebinger, Martin, Grimes, H. Leighton, Robinson, Giles W., Gajjar, Amar, Mynarek, Martin, von Hoff, Katja, Rutkowski, Stefan, Pietsch, Torsten, Scheurlen, Wolfram, Felsberg, Jörg, Reifenberger, Guido, Kulozik, Andreas E., von Deimling, Andreas, Witt, Olaf, Eils, Roland, Gilbertson, Richard J., Korshunov, Andrey, Taylor, Michael D., Lichter, Peter, Korbel, Jan O., Wechsler-Reya, Robert J., Pfister, Stefan M.

“…Medulloblastoma is a highly malignant paediatric brain tumour currently treated with a combination of surgery, radiation and chemotherapy, posing a…”
Get full text

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis by Ramaswamy, Vijay, Hielscher, Thomas, Mack, Stephen C, Lassaletta, Alvaro, Lin, Tong, Pajtler, Kristian W, Jones, David T W, Luu, Betty, Cavalli, Florence M G, Aldape, Kenneth, Remke, Marc, Mynarek, Martin, Rutkowski, Stefan, Gururangan, Sridharan, McLendon, Roger E, Lipp, Eric S, Dunham, Christopher, Hukin, Juliette, Eisenstat, David D, Fulton, Dorcas, van Landeghem, Frank K H, Santi, Mariarita, van Veelen, Marie-Lise C, Van Meir, Erwin G, Osuka, Satoru, Fan, Xing, Muraszko, Karin M, Tirapelli, Daniela P C, Oba-Shinjo, Sueli M, Marie, Suely K N, Carlotti, Carlos G, Lee, Ji Yeoun, Rao, Amulya A Nageswara, Giannini, Caterina, Faria, Claudia C, Nunes, Sofia, Mora, Jaume, Hamilton, Ronald L, Hauser, Peter, Jabado, Nada, Petrecca, Kevin, Jung, Shin, Massimi, Luca, Zollo, Massimo, Cinalli, Giuseppe, Bognár, László, Klekner, Almos, Hortobágyi, Tibor, Leary, Sarah, Ermoian, Ralph P, Olson, James M, Leonard, Jeffrey R, Gardner, Corrine, Grajkowska, Wieslawa A, Chambless, Lola B, Cain, Jason, Eberhart, Charles G, Ahsan, Sama, Massimino, Maura, Giangaspero, Felice, Buttarelli, Francesca R, Packer, Roger J, Emery, Lyndsey, Yong, William H, Soto, Horacio, Liau, Linda M, Everson, Richard, Grossbach, Andrew, Shalaby, Tarek, Grotzer, Michael, Karajannis, Matthias A, Zagzag, David, Wheeler, Helen, von Hoff, Katja, Alonso, Marta M, Tuñon, Teresa, Schüller, Ulrich, Zitterbart, Karel, Sterba, Jaroslav, Chan, Jennifer A, Guzman, Miguel, Elbabaa, Samer K, Colman, Howard, Dhall, Girish, Fisher, Paul G, Fouladi, Maryam, Gajjar, Amar, Goldman, Stewart, Hwang, Eugene, Kool, Marcel, Ladha, Harshad, Vera-Bolanos, Elizabeth, Wani, Khalida, Lieberman, Frank, Mikkelsen, Tom, Omuro, Antonio M, Pollack, Ian F, Prados, Michael, Robins, H Ian, Soffietti, Riccardo

“…Posterior fossa ependymoma comprises two distinct molecular variants termed EPN_PFA and EPN_PFB that have a distinct biology and natural history. The…”
Get full text

Cytogenetic Prognostication Within Medulloblastoma Subgroups by SHIH, David J. H, NORTHCOTT, Paul A, GARZIA, Livia, PEACOCK, John, MACK, Stephen C, XIAOCHONG WU, ROLIDER, Adi, MORRISSY, A. Sorana, CAVALLI, Florence M. G, JONES, David T. W, ZITTERBART, Karel, FARIA, Claudia C, REMKE, Marc, SCHÜLLER, Ulrich, KREN, Leos, KUMABE, Toshihiro, TOMINAGA, Teiji, YOUNG SHIN RA, GARAMI, Miklós, HAUSER, Peter, CHAN, Jennifer A, ROBINSON, Shenandoah, BOGNAR, László, KORSHUNOV, Andrey, KLEKNER, Almos, SAAD, Ali G, LIAU, Linda M, ALBRECHT, Steffen, FONTEBASSO, Adam, CINALLI, Giuseppe, DE ANTONELLIS, Pasqualino, ZOLLO, Massimo, COOPER, Michael K, THOMPSON, Reid C, RAMASWAMY, Vijay, BAILEY, Simon, LINDSEY, Janet C, DI ROCCO, Concezio, MASSIMI, Luca, MICHIELS, Erna M. C, SCHERER, Stephen W, PHILLIPS, Joanna J, GUPTA, Nalin, XING FAN, MURASZKO, Karin M, KOOL, Marcel, VIBHAKAR, Rajeev, EBERHART, Charles G, FOULADI, Maryam, LACH, Boleslaw, SHIN JUNG, WECHSLER-REYA, Robert J, FEVRE-MONTANGE, Michelle, JOUVET, Anne, JABADO, Nada, POLLACK, Ian F, LUU, Betty, YUAN YAO, XIN WANG, DUBUC, Adrian M

“…Medulloblastoma comprises four distinct molecular subgroups: WNT, SHH, Group 3, and Group 4. Current medulloblastoma protocols stratify patients based on…”
Get full text

LG-60OBJECTIVE RESPONSE TO VEMURAFENIB IN A CHILD TREATED FOR METASTATIC DESMOPLASTIC INFANTILE ASTROCYTOMA by Pavelka, Zdenek, Berkovcova, Jitka, Skotakova, Jarmila, Zitterbart, Karel, Sterba, Jaroslav

Get full text

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma by Remke, Marc, Ramaswamy, Vijay, Peacock, John, Shih, David J. H., Koelsche, Christian, Northcott, Paul A., Hill, Nadia, Cavalli, Florence M. G., Kool, Marcel, Wang, Xin, Mack, Stephen C., Barszczyk, Mark, Morrissy, A. Sorana, Wu, Xiaochong, Agnihotri, Sameer, Luu, Betty, Jones, David T. W., Garzia, Livia, Dubuc, Adrian M., Zhukova, Nataliya, Vanner, Robert, Kros, Johan M., French, Pim J., Van Meir, Erwin G., Vibhakar, Rajeev, Zitterbart, Karel, Chan, Jennifer A., Bognár, László, Klekner, Almos, Lach, Boleslaw, Jung, Shin, Saad, Ali G., Liau, Linda M., Albrecht, Steffen, Zollo, Massimo, Cooper, Michael K., Thompson, Reid C., Delattre, Oliver O., Bourdeaut, Franck, Doz, François F., Garami, Miklós, Hauser, Peter, Carlotti, Carlos G., Van Meter, Timothy E., Massimi, Luca, Fults, Daniel, Pomeroy, Scott L., Kumabe, Toshiro, Ra, Young Shin, Leonard, Jeffrey R., Elbabaa, Samer K., Mora, Jaume, Rubin, Joshua B., Cho, Yoon-Jae, McLendon, Roger E., Bigner, Darell D., Eberhart, Charles G., Fouladi, Maryam, Wechsler-Reya, Robert J., Faria, Claudia C., Croul, Sidney E., Huang, Annie, Bouffet, Eric, Hawkins, Cynthia E., Dirks, Peter B., Weiss, William A., Schüller, Ulrich, Pollack, Ian F., Rutkowski, Stefan, Meyronet, David, Jouvet, Anne, Fèvre-Montange, Michelle, Jabado, Nada, Perek-Polnik, Marta, Grajkowska, Wieslawa A., Kim, Seung-Ki, Rutka, James T., Malkin, David, Tabori, Uri, Pfister, Stefan M., Korshunov, Andrey, von Deimling, Andreas, Taylor, Michael D.

“…Telomerase reverse transcriptase ( TERT ) promoter mutations were recently shown to drive telomerase activity in various cancer types, including…”
Get full text

Overexpression of the Delta Np73 isoform is associated with centrosome amplification in brain tumor cell lines by Mikulenkova, Erika, Neradil, Jakub, Zitterbart, Karel, Sterba, Jaroslav, Veselska, Renata

“…The p73 protein is a member of the p53 family, and this protein is known to be essential for the maintenance of genomic stability, DNA repair, and apoptosis…”
Get full text

Cancer stem cell markers in pediatric sarcomas: Sox2 is associated with tumorigenicity in immunodeficient mice by Skoda, Jan, Nunukova, Alena, Loja, Tomas, Zambo, Iva, Neradil, Jakub, Mudry, Peter, Zitterbart, Karel, Hermanova, Marketa, Hampl, Ales, Sterba, Jaroslav, Veselska, Renata

“…The three most frequent pediatric sarcomas, i.e., Ewing’s sarcoma, osteosarcoma, and rhabdomyosarcoma, were examined in this study: three cell lines derived…”
Get full text

EGFR signaling in the HGG-02 glioblastoma cell line with an unusual loss of EGFR gene copy by SKODA, JAN, NERADIL, JAKUB, ZITTERBART, KAREL, STERBA, JAROSLAV, VESELSKA, RENATA

“…Epidermal growth factor receptor (EGFR) gene amplification and the overexpression of EGFR are described as common features of glioblastoma multiforme (GBM)…”
Get full text

Subependymal giant cell astrocytoma associated with tuberous sclerosis complex -  pharmacological treatment using mTOR inhibitors by Zitterbart, K

“…Tuberous sclerosis complex is a neurocutaneous syndrome that results from a germline mutation in TSC1 or TSC2 genes. The pathogenic activation of mTORC1 leads…”
Get more information

Overexpression of the ∆Np73 isoform is associated with centrosome amplification in brain tumor cell lines by Mikulenkova, Erika, Neradil, Jakub, Zitterbart, Karel, Sterba, Jaroslav, Veselska, Renata

“…The p73 protein is a member of the p53 family, and this protein is known to be essential for the maintenance of genomic stability, DNA repair, and apoptosis…”
Get full text

Expression of nestin, CD133 and ABCG2 in relation to the clinical outcome in pediatric sarcomas by Zambo, Iva, Hermanova, Marketa, Zapletalova, Danica, Skoda, Jan, Mudry, Peter, Kyr, Michal, Zitterbart, Karel, Sterba, Jaroslav, Veselska, Renata

“…Nestin, CD133 and ABCG2 are recently discussed as putative markers, co-expression of which might determine a cancer stem cell (CSC) phenotype in sarcomas. Our…”
Get more information

MB-88QUANTITATIVE PROTEOMIC PROFILING IN MEDULLOBLASTOMA RECAPITULATES SUBGROUPING BASED ON TRANSCRIPTIONAL PROFILES by Dvorakova, Petra, Kyr, Michal, Nekulova, Marta, Jezova, Marta, Pavelka, Zdenek, Slaby, Ondrej, Sterba, Jaroslav, Vojtesek, Borivoj, Hernychova, Lenka, Zitterbart, Karel

Get full text

LOX/COX inhibitors enhance the antineoplastic effects of all-trans retinoic acid in osteosarcoma cell lines by Krzyzankova, Miroslava, Chovanova, Silvia, Chlapek, Petr, Radsetoulal, Matej, Neradil, Jakub, Zitterbart, Karel, Sterba, Jaroslav, Veselska, Renata

“…The induced differentiation of tumor cells into mature phenotypes is a promising strategy in cancer therapy. In this study, the effects of combined treatment…”
Get full text

Intracellular distribution of the ΔNp73 protein isoform in medulloblastoma cells: a study with newly generated rabbit polyclonal antibodies by Veselska, Renata, Neradil, Jakub, Nekulova, Marta, Dobrucka, Lucia, Vojtesek, Borivoj, Sterba, Jaroslav, Zitterbart, Karel

“…The p73 protein is a member of the p53 family of transcription factors that has two N-terminal isoforms: the TAp73 isoform is reported to have a tumor…”
Get full text

The ATRA-induced differentiation of medulloblastoma cells is enhanced with LOX/COX inhibitors: an analysis of gene expression by Chlapek, Petr, Neradil, Jakub, Redova, Martina, Zitterbart, Karel, Sterba, Jaroslav, Veselska, Renata

“…A detailed analysis of the expression of 440 cancer-related genes was performed after the combined treatment of medulloblastoma cells with all-trans retinoic…”
Get full text