Search Results - "ZISSEL, G"

Inhibition of PDGF, VEGF and FGF signalling attenuates fibrosis by Chaudhary, N. I, Roth, G. J, Hilberg, F, Muller-Quernheim, J, Prasse, A, Zissel, G, Schnapp, A, Park, J. E

“…BIBF 1000 is a small molecule inhibitor targeting the receptor kinases of platelet-derived growth factor (PDGF), basic fibroblast growth factor and vascular…”
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The value of bronchoalveolar lavage for discrimination between healthy and diseased individuals by Frye, B. C., Schupp, J. C., Rothe, M. E., Köhler, T. C., Prasse, A., Zissel, G., Vach, W., Müller‐Quernheim, J.

“…Background Bronchoalveolar lavage (BAL) is standard diagnostic procedure. Procedural recommendations have been made by pneumological societies including normal…”
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A Vicious Circle of Alveolar Macrophages and Fibroblasts Perpetuates Pulmonary Fibrosis via CCL18 by Prasse, Antje, Pechkovsky, Dmitri V, Toews, Galen B, Jungraithmayr, Wolfgang, Kollert, Florian, Goldmann, Torsten, Vollmer, Ekkehard, Muller-Quernheim, Joachim, Zissel, Gernot

“…Recently, models of macrophage activation have been revised. Macrophages stimulated with Th2 cytokines have been classified as alternatively activated. This…”
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Diagnoses of chronic beryllium disease within cohorts of sarcoidosis patients by Muller-Quernheim, J, Gaede, K. I, Fireman, E, Zissel, G

“…An increase in chronic beryllium disease (CBD) has been suggested due to higher industrial use of beryllium alloys. Since occupational CBD is a perfect…”
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Genotype-corrected reference values for serum angiotensin-converting enzyme by Biller, H, Zissel, G, Ruprecht, B, Nauck, M, Busse Grawitz, A, Muller-Quernheim, J

“…The deletion (D)/insertion (I) polymorphism in intron 16 of the angiotensin-converting enzyme (ACE) gene has the greatest impact on serum ACE level in…”
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New Pathogenetic Concepts and Early Pharmacological Studies in Sarcoidosis by Schupp, J C, Frye, B C, Zissel, G, Müller-Quernheim, J

“…The etiology of sarcoidosis is still elusive, yet there has been considerable progress in various areas of basic and clinical research. This review focuses on…”
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Alveolar macrophages are the main source for tumour necrosis factor-α in patients with sarcoidosis by FEHRENBACH, H, ZISSEL, G, GOLDMANN, T, TSCHERNIG, T, VOLLMER, E, PABST, R, MÜLLER-QUERNHEIM, J

“…Tumour necrosis factor (TNF)-alpha is known to play a major role in the formation of noncaseating granuloma, a hallmark of sarcoidosis. The main cellular…”
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Interleukin-13 acts as an apoptotic effector on lung epithelial cells and induces pro-fibrotic gene expression in lung fibroblasts by Borowski, A., Kuepper, M., Horn, U., Knüpfer, U., Zissel, G., Höhne, K., Luttmann, W., Krause, S., Virchow Jr, J. C., Friedrich, K.

“…Summary Background IL‐13 promotes acute allergic asthma and is discussed to play a role in late asthmatic features such as fibrotic processes and airway…”
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Generation and evaluation of a monoclonal antibody, designated MAdL, as a new specific marker for adenocarcinomas of the lung by Schultz, H, Marwitz, S, Baron-Lühr, B, Zissel, G, Kugler, C, Rabe, K F, Zabel, P, Vollmer, E, Gerdes, J, Goldmann, T

“…Background: Different therapy regimens in non-small-cell lung cancer (NSCLC) are of rising clinical importance, and therefore a clear-cut subdifferentiation is…”
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Local administration of uridine suppresses the cardinal features of asthmatic airway inflammation by Müller, T., Grimm, M., De Vieira, R. P., Cicko, S., Dürk, T., Sorichter, S., Zissel, G., Idzko, M.

“…Summary Background The immuno‐modulatory properties of nucleotides such as adenosine or inosine, have been described extensively. Recently, the nucleoside…”
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Gene polymorphisms of ACE and the angiotensin receptor AT2R1 influence serum ACE levels in sarcoidosis by Biller, H, Ruprecht, B, Gaede, K I, Müller-Quernheim, J, Zissel, G

“…Angiotensin converting enzyme (ACE) is thought to influence susceptibility, disease progression, and/or outcome of sarcoidosis by functional…”
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59PD SERUM LEVEL OF CC-CHEMOKINE LIGAND 18 (PULMONARY ACTIVATION-REGULATED CHEMOKINE) IN PATIENTS WITH NON SMALL CELL LUNG CANCER by Pl¨ones, T, M¨uller-Quernheim, U, Burger, M, Veelken, H, Passlick, B, Zissel, G

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Pattern of NOS2 and NOS3 mRNA expression in human A549 cells and primary cultured AEC II by Pechkovsky, D V, Zissel, G, Goldmann, T, Einhaus, M, Taube, C, Magnussen, H, Schlaak, M, Müller-Quernheim, J

“…The human alveolar type II epithelium-like cell line A549 expresses nitric oxide synthase type 2 (NOS2), but not NOS3, and produces nitric oxide (NO) upon…”
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Human alveolar epithelial cells induce nitric oxide synthase-2 expression in alveolar macrophages by Pechkovsky, D.V, Zissel, G, Stamme, C, Goldmann, T, Ari Jaffe, H, Einhaus, M, Taube, C, Magnussen, H, Schlaak, M, Muller-Quernheim, J

“…It was hypothesized that cell-to-cell interaction between human alveolar macrophages (AM) and alveolar epithelium, might be an important factor leading to…”
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Anti-inflammatory cytokine release by alveolar macrophages in pulmonary sarcoidosis by Zissel, G, Homolka, J, Schlaak, J, Schlaak, M, Müller-Quernheim, J

“…Sarcoidosis is a systemic, granulomatous disorder with a high rate of spontaneous remission indicating the presence of antiinflammatory mechanisms…”
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Th1/Th2 cell distribution in pulmonary sarcoidosis by Bäumer, I, Zissel, G, Schlaak, M, Müller-Quernheim, J

“…Cytokines released by T lymphocytes activated in the course of sarcoidosis, e.g., interleukin-2 (IL-2) and interferon-gamma (IFN-gamma), indicate the presence…”
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Analysis of the Kveim-Siltzbach test reagent for bacterial DNA by RICHTER, E, KATARIA, Y. P, ZISSEL, G, HOMOLKA, J, SCHLAAK, M, MULLER-QUERNHEIM, J

“…The sarcoid spleen-derived reagent for the Kveim-Siltzbach test (KST) elicits a sarcoid-specific, granulomatous, cutaneous response used to establish the…”
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Assessment of transcriptional gene activity in situ by application of HOPE-fixed, paraffin-embedded tissues by Goldmann, T, Wiedorn, K H, Kühl, H, Olert, J, Branscheid, D, Pechkovsky, D, Zissel, G, Galle, J, Müller-Quernheim, J, Vollmer, E

“…We report the use of HOPE-fixation (HOPE = Hepes-Glutamic acid buffer mediated Organic solvent Protection Effect) for specimens utilized for in situ…”
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Sarcoidosis: historical perspective and immunopathogenesis (part I) by Zissel, G., Müller-Quernheim, J.

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(1229) Fibroblast Activation Protein Alpha (fapa) in Chronic Lung Allograft Dysfunction by Moneke, I., Burkle, J., Pfaffendorf, E., Bronsert, P., Zissel, G., Faendrich, S., Passlick, B., Diederichs, S., Jungraithmayr, W.

“…Chronic lung allograft dysfunction (CLAD) limits survival after lung transplantation (Tx). CLAD is characterized by a progressive fibrosis within small airways…”
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