Search Results - "ZIPORI, Dov"
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The nature of stem cells: state rather than entity
Published in Nature reviews. Genetics (01-11-2004)“…Stem cells are endowed with self-renewal and multipotential differentiation capacities. Contrary to the expectation that stem cells would selectively express…”
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The Origins of Mesenchymal Stromal Cell Heterogeneity
Published in Stem cell reviews (01-09-2011)“…Cultured mesenchymal stromal cell (MSC) populations are best characterized by the capacity of some cells within this population to differentiate into…”
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The Stem State: Plasticity Is Essential, Whereas Self‐Renewal and Hierarchy Are Optional
Published in Stem cells (Dayton, Ohio) (01-06-2005)“…The prevailing stem cell concept is derived from the large body of evidence available on the structure of the blood‐generating system. Hemopoiesis is organized…”
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The Hemopoietic Stem Cell Niche Versus the Microenvironment of the Multiple Myeloma-Tumor Initiating Cell
Published in Cancer microenvironment (01-12-2010)“…Multiple myeloma cells are reminiscent of hemopoietic stem cells in their strict dependence upon the bone marrow microenvironment. However, from all other…”
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p53 plays a role in mesenchymal differentiation programs, in a cell fate dependent manner
Published in PloS one (12-11-2008)“…The tumor suppressor p53 is an important regulator that controls various cellular networks, including cell differentiation. Interestingly, some studies suggest…”
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The stem state: mesenchymal plasticity as a paradigm
Published in Current stem cell research and therapy (01-01-2006)“…The mesenchyme is a remarkably plastic tissue in the embryo. Recent studies have led to the discovery of mesenchymal cells in the adult organism that can…”
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Environmental guidance of normal and tumor cell plasticity: epithelial mesenchymal transitions as a paradigm
Published in Blood (15-04-2004)“…Epithelial mesenchymal transitions are a remarkable example of cellular plasticity. These transitions are the hallmark of embryo development, are pivotal in…”
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Cell Isolation Induces Fate Changes of Bone Marrow Mesenchymal Cells Leading to Loss or Alternatively to Acquisition of New Differentiation Potentials
Published in Stem cells (Dayton, Ohio) (01-08-2014)“…Mesenchymal stromal cell populations include a fraction, termed mesenchymal stem cells, exhibiting multipotency. Other cells within this population possess a…”
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Dependence of Human Stem Cell Engraftment and Repopulation of NOD/SCID Mice on CXCR4
Published in Science (American Association for the Advancement of Science) (05-02-1999)“…Stem cell homing and repopulation are not well understood. The chemokine stromal cell-derived factor-1 (SDF-1) and its receptor CXCR4 were found to be critical…”
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Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell function
Published in The Journal of clinical investigation (01-12-2000)“…The chemokine stromal-derived factor-1 (SDF-1) controls many aspects of stem cell function. Details of its regulation and sites of production are currently…”
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The Role of Activin A in Regulation of Hemopoiesis
Published in Stem cells (Dayton, Ohio) (01-01-2002)“…Activin A, a cytokine member of the transforming growth factor‐β superfamily, is expressed locally by the mesenchymal component of the hemopoietic…”
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Stress as a fundamental theme in cell plasticity
Published in Biochimica et biophysica acta (01-04-2015)“…Over a decade of intensive investigation of the possible plasticity of mammalian cells has eventually substantiated that mammalian species are endowed with a…”
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Role of activin A in negative regulation of normal and tumor B lymphocytes
Published in Journal of leukocyte biology (01-06-2001)“…Activin A, a member of the transforming growth factor β superfamily, has a wide spread expression pattern and pleiotropic functions. In thisoverview we…”
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Activin β A in term placenta and its correlation with placental inflammation in parturients having epidural or systemic meperidine analgesia: a randomized study
Published in Journal of clinical anesthesia (01-05-2007)“…Abstract Study Objective To investigate the immunohistochemical localization of β A subunit of activin A in human term placenta, as a marker for placental…”
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PSF and p54nrb/NonO – multi‐functional nuclear proteins
Published in FEBS letters (06-11-2002)“…Proteins are often referred to in accordance with the activity with which they were first associated or the organelle in which they were initially identified…”
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The Mesenchymal Stroma Negatively Regulates B Cell Lymphopoiesis through the Expression of Activin A
Published in Annals of the New York Academy of Sciences (01-05-2003)“…: The negative control of B cell generation is only partially resolved. We assessed the role of activin A in regulation of B lymphopoiesis in view of its…”
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Transition of Endothelium to Cartilage and Bone
Published in Cell stem cell (07-01-2011)“…Mesenchymal stromal cells (MSCs) are capable of differentiating into bone-forming osteoblasts. A recent Nature Medicine study ( Medici et al., 2010) shows that…”
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Toll-like receptors and their ligands control mesenchymal stem cell functions
Published in Blood (15-02-2007)“…Mesenchymal stem cells (MSCs) are widespread in adult organisms and may be involved in tissue maintenance and repair as well as in the regulation of…”
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PSF and p54(nrb)/NonO--multi-functional nuclear proteins
Published in FEBS letters (06-11-2002)“…Proteins are often referred to in accordance with the activity with which they were first associated or the organelle in which they were initially identified…”
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