Search Results - "ZIPKIN, R. E"
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Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth
Published in Journal of lipid research (01-03-1995)“…Analogs and homologs of PDMP were synthesized, based on its structure (D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol). This compound had previously…”
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Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
Published in Nature (11-09-2003)“…In diverse organisms, calorie restriction slows the pace of ageing and increases maximum lifespan. In the budding yeast Saccharomyces cerevisiae, calorie…”
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N-Oleoyldopamine, a Novel Endogenous Capsaicin-like Lipid That Produces Hyperalgesia
Published in The Journal of biological chemistry (18-04-2003)“…N-Arachidonoyldopamine (NADA) was recently identified as an endogenous ligand for the vanilloid type 1 receptor (VR1). Further analysis of the bovine striatal…”
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Identification of a New Class of Molecules, the Arachidonyl Amino Acids, and Characterization of One Member That Inhibits Pain
Published in The Journal of biological chemistry (16-11-2001)“…In mammals, specific lipids and amino acids serve as crucial signaling molecules. In bacteria, conjugates of lipids and amino acids (referred to as lipoamino…”
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Rest/exercise thallium myocardial perfusion imaging: a new and rapid technique to evaluate coronary artery disease
Published in Nuclear medicine communications (01-06-1993)“…Twenty-six patients underwent conventional exercise/4-h redistribution thallium myocardial perfusion imaging as well as rest/exercise imaging on different…”
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Mitral valve replacement in dilated canine hearts with chronic mitral regurgitation. Importance of the mitral subvalvular apparatus
Published in Circulation (New York, N.Y.) (01-11-1991)“…The importance of the mitral subvalvular apparatus in terms of left ventricular (LV) mechanics and energetic efficiency in the chronically dilated canine heart…”
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A general and stereocontrolled total synthesis of leukotriene B4 and analogs
Published in Journal of the American Chemical Society (01-06-1984)Get full text
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Preparation of omega trideuterated sulfidopeptide leukotrienes: analysis by FAB/MS
Published in Prostaglandins (01-02-1989)“…C-20 Trideuterated leukotriene A4 methyl ester was prepared by Wittig condensation of a deuterated C9-phosphonium salt with a C11-epoxydienal. It was then…”
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Pentoxifylline and aplastic anemia
Published in Annals of internal medicine (01-09-1987)Get more information
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Desensitization of the leukotriene B4 receptor by partial agonists
Published in Advances in prostaglandin, thromboxane, and leukotriene research (1991)Get more information
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Metabolism of cyclooxygenase and lipoxygenase products by 15-prostaglandin dehydrogenase from human HL-60 leukemia cells
Published in Agents and Actions (01-08-1987)“…A number of prostaglandins and mono-hydroxylated fatty acids were investigated as substrates for NAD-dependent 15-prostaglandin dehydrogenase (15-PGDH)…”
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Development and application of a membrane receptor assay for leukotriene B4
Published in Agents and Actions (01-06-1989)“…5(S),12(R)-dihydroxy-6-cis-8,10 trans-14-cis-eicosatetraenoic acid (LTB4) is a potent inflammatory mediator generated by human cells. A receptor assay using…”
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Direct cardiovascular actions of two metabolites of linoleic acid
Published in Life sciences (1973) (1990)“…Two newly discovered oxidation products of linoleic acid (i.e., 9,10-epoxy-12-octadecenoate termed Leukotoxin A, and 12,13-epoxy-9-octadecenoate termed…”
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Rabbit and human liver contain a novel pentacyclic triterpene ester with acyl-CoA: cholesterol acyltransferase inhibitory activity
Published in The Journal of biological chemistry (15-05-1990)“…Acyl-coenzyme A (CoA):cholesterol acyltransferase (ACAT) catalyzes the intracellular fatty acid esterification of cholesterol and is thought to play a key role…”
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Comparative study of the angiographic morphology of coronary artery lesions treated with PTCA, directional coronary atherectomy, or high-speed rotational ablation
Published in Catheterization and cardiovascular diagnosis (01-09-1994)“…To evaluate trends in morphology-based intervention selection, series of 110 consecutive procedures of each of three devices, percutaneous transluminal balloon…”
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