Search Results - "ZIENOLDDINY, Shan"
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Chrono-modulated effects of external stressors on oxidative stress and damage in humans: A scoping review on night shift work
Published in Environment international (01-08-2023)“…[Display omitted] Oxidative stress and tissue damage (OSD) play a pivotal role as an early-stage process in chronic disease pathogenesis. However, there has…”
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In vitro-in vivo correlations of pulmonary inflammogenicity and genotoxicity of MWCNT
Published in Particle and fibre toxicology (23-07-2021)“…Abstract Background Multi-walled carbon nanotubes (MWCNT) have received attention due to extraordinary properties, resulting in concerns for occupational…”
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Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma
Published in Frontiers of medicine (01-04-2021)“…Although genome-wide association studies have identified more than eighty genetic variants associated with non-small cell lung cancer (NSCLC) risk, biological…”
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Systematic review of mechanistic evidence for TiO2 nanoparticle-induced lung carcinogenicity
Published in Nanotoxicology (01-08-2024)“…Nano-sized titanium dioxide particles (TiO2 NPs) are a high-production volume nanomaterial widely used in the paints, cosmetics, food and photovoltaics…”
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Particulate matter constituents trigger the formation of extracellular amyloid β and Tau -containing plaques and neurite shortening in vitro
Published in Nanotoxicology (01-06-2024)“…Air pollution is an environmental factor associated with an increased risk of neurodegenerative diseases, such as Alzheimer's and Parkinson's, characterized by…”
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High aspect ratio nanomaterial-induced macrophage polarization is mediated by changes in miRNA levels
Published in Frontiers in immunology (27-01-2023)“…Inhalation of nanomaterials may induce inflammation in the lung which if left unresolved can manifest in pulmonary fibrosis. In these processes, alveolar…”
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Impact of individual level uncertainty of lung cancer polygenic risk score (PRS) on risk stratification
Published in Genome medicine (05-02-2024)“…Although polygenic risk score (PRS) has emerged as a promising tool for predicting cancer risk from genome-wide association studies (GWAS), the…”
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Abstract A01: Mechanisms of breast cancer risk in shift workers: Epigenetic changes in the circadian pathway
Published in Cancer research (Chicago, Ill.) (15-11-2017)“…Abstract Occupational factors such as shiftwork and especially night work that involves disruption of the circadian rhythm can increase breast cancer risk…”
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Advanced Respiratory Models for Hazard Assessment of Nanomaterials—Performance of Mono-, Co- and Tricultures
Published in Nanomaterials (Basel, Switzerland) (29-07-2022)“…Advanced in vitro models are needed to support next-generation risk assessment (NGRA), moving from hazard assessment based mainly on animal studies to the…”
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O-125 THE ROLE OF STAKEHOLDERS ENGAGEMENT TO DEFINE EUROPEAN TRAINING PRACTICES ON NANOMATERIALS AND ADVANCED MATERIALS SAFETY AND HEALTH AT WORK
Published in Occupational medicine (Oxford) (05-07-2024)“…Abstract Introduction Training of personnel engaged in the research, production, and use of nanomaterials (NMs) and advanced materials (AdMa), as well as those…”
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Night Work and Breast Cancer Risk Among Norwegian Nurses: Assessment by Different Exposure Metrics
Published in American journal of epidemiology (01-06-2011)“…Associations between night work and breast cancer risk were investigated in a nested case-control study within a cohort of 49,402 Norwegian nurses. A total of…”
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CYP2A6 Activity and Cigarette Consumption Interact in Smoking-Related Lung Cancer Susceptibility
Published in Cancer research (Chicago, Ill.) (15-02-2024)“…Cigarette smoke, containing both nicotine and carcinogens, causes lung cancer. However, not all smokers develop lung cancer, highlighting the importance of the…”
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O5B.1 Workplace exposure assessment (WEA), skin barrier function, and occurrence of hand eczema among workers handling drilling waste in norway
Published in Occupational and environmental medicine (London, England) (01-04-2019)“…IntroductionKnowledge on skin exposure and the occurrence of hand eczema (HE) among workers handling drilling waste from oil and gas drilling is scarce.M and…”
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Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk
Published in Human molecular genetics (23-08-2022)“…Abstract Differences by sex in lung cancer incidence and mortality have been reported which cannot be fully explained by sex differences in smoking behavior,…”
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Toxicoproteomic effects of carbon nanotubes on chronically exposed human lung cells
Published in Toxicology letters (20-10-2017)Get full text
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Genome‐wide association study of INDELs identified four novel susceptibility loci associated with lung cancer risk
Published in International journal of cancer (15-05-2020)“…Genome‐wide association studies (GWAS) have identified 45 susceptibility loci associated with lung cancer. Only less than SNPs, small insertions and deletions…”
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Mosaic Chromosomal Alterations Are Associated With Increased Lung Cancer Risk: Insight From the INTEGRAL-ILCCO Cohort Analysis
Published in Journal of thoracic oncology (01-08-2023)“…Mosaic chromosomal alterations (mCAs) detected in white blood cells represent a type of clonal hematopoiesis (CH) that is understudied compared with CH-related…”
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Abstract 932: Molecular characterization of transcription factors binding to the cancer-related interleukin-1 B gene polymorphisms
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Pulmonary inflammation together with chemical exposure may potentiate the carcinogenic process, underlining the importance of inflammation in cancer…”
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Breast Cancer Among Nurses: Is the Intensity of Night Work Related to Hormone Receptor Status?
Published in American journal of epidemiology (01-07-2013)“…The aim of this study was to investigate whether night work is related to breast cancer receptor status. The effect of night work on the risk of estrogen…”
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97 Transferability and Reproducibility of Exposed Air-Liquid Interface co-Culture Lung Models
Published in Annals of work exposures and health (10-05-2023)“…Abstract The establishment of reliable and robust in vitro models for hazard assessment, moving away from animal testing, requires evaluation of model…”
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