Search Results - "ZIATS, Mark N"

Aberrant Expression of Long Noncoding RNAs in Autistic Brain by Ziats, Mark N., Rennert, Owen M.

“…The autism spectrum disorders (ASD) have a significant hereditary component, but the implicated genetic loci are heterogeneous and complex. Consequently, there…”
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Altered glial marker expression in autistic post-mortem prefrontal cortex and cerebellum by Edmonson, Catherine, Ziats, Mark N, Rennert, Owen M

“…The cellular mechanism(s) underlying autism spectrum disorders (ASDs) are not completely understood, but ASDs are thought to ultimately result from disrupted…”
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Expression profiling of autism candidate genes during human brain development implicates central immune signaling pathways by Ziats, Mark N, Rennert, Owen M

“…The Autism Spectrum Disorders (ASD) represent a clinically heterogeneous set of conditions with strong hereditary components. Despite substantial efforts to…”
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Genotype–phenotype analysis of 523 patients by genetics evaluation and clinical exome sequencing by Ziats, Mark N., Ahmad, Ayesha, Bernat, John A., Fisher, Rachel, Glassford, Megan, Hannibal, Mark C., Jacher, Joseph E., Weiser, Natasha, Keegan, Catherine E., Lee, Kristen N., Marzulla, Tessa B., O’Connor, Bridget C., Quinonez, Shane C., Seemann, Lauren, Turner, Lauren, Bielas, Stephanie, Harris, Nicholas L., Ogle, Jacob D., Innis, Jeffrey W., Martin, Donna M.

“…Background As clinical exome sequencing (CES) becomes more common, understanding which patients are most likely to benefit and in what manner is critical for…”
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Functional genomics analysis of Phelan-McDermid syndrome 22q13 region during human neurodevelopment by Ziats, Catherine A, Grosvenor, Luke P, Sarasua, Sara M, Thurm, Audrey E, Swedo, Susan E, Mahfouz, Ahmed, Rennert, Owen M, Ziats, Mark N

“…Phelan-McDermid syndrome (PMS) is a neurodevelopmental disorder characterized by varying degrees of intellectual disability, severely delayed language…”
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A Non-inflammatory Role for Microglia in Autism Spectrum Disorders by Edmonson, Catherine A, Ziats, Mark N, Rennert, Owen M

“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interaction, difficulties with language, and…”
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The complex behavioral phenotype of 15q13.3 microdeletion syndrome by Ziats, Mark N., Goin-Kochel, Robin P., Berry, Leandra N., Ali, May, Ge, Jun, Guffey, Danielle, Rosenfeld, Jill A., Bader, Patricia, Gambello, Michael J., Wolf, Varina, Penney, Lynette S., Miller, Ryan, Lebel, Robert Roger, Kane, Jeffrey, Bachman, Kristine, Troxell, Robin, Clark, Gary, Minard, Charles G., Stankiewicz, Pawel, Beaudet, Arthur, Schaaf, Christian P.

“…Chromosome 15q13.3 represents a hotspot for genomic rearrangements due to repetitive sequences mediating nonallelic homologous recombination. Deletions of…”
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Editorial: Non-Coding RNAs in Neurodevelopmental Disorders by Rennert, Owen M, Ziats, Mark N

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A systematic variant annotation approach for ranking genes associated with autism spectrum disorders by Larsen, Eric, Menashe, Idan, Ziats, Mark N, Pereanu, Wayne, Packer, Alan, Banerjee-Basu, Sharmila

“…The search for genetic factors underlying autism spectrum disorders (ASD) has led to the identification of hundreds of genes containing thousands of variants…”
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Toward a Pathway-Driven Clinical-Molecular Framework for Classifying Autism Spectrum Disorders by Ziats, Catherine A., Rennert, Owen M., Ziats, Mark N.

“…The current classification system of neurodevelopmental disorders is based on clinical criteria; however, this method alone fails to incorporate what is now…”
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Idiopathic Autism: Cellular and Molecular Phenotypes in Pluripotent Stem Cell-Derived Neurons by Liu, Xiaozhuo, Campanac, Emilie, Cheung, Hoi-Hung, Ziats, Mark N., Canterel-Thouennon, Lucile, Raygada, Margarita, Baxendale, Vanessa, Pang, Alan Lap-Yin, Yang, Lu, Swedo, Susan, Thurm, Audrey, Lee, Tin-Lap, Fung, Kwok-Pui, Chan, Wai-Yee, Hoffman, Dax A., Rennert, Owen M.

“…Autism spectrum disorder is a complex neurodevelopmental disorder whose pathophysiology remains elusive as a consequence of the unavailability for study of…”
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The Evolving Diagnostic and Genetic Landscapes of Autism Spectrum Disorder by Ziats, Mark N, Rennert, Owen M

“…The autism spectrum disorders (ASD) are a heterogeneous set of neurodevelopmental syndromes defined by impairments in verbal and non-verbal communication,…”
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Shared Pathways Among Autism Candidate Genes Determined by Co-expression Network Analysis of the Developing Human Brain Transcriptome by Mahfouz, Ahmed, Ziats, Mark N., Rennert, Owen M., Lelieveldt, Boudewijn P.F., Reinders, Marcel J.T.

“…Autism spectrum disorder (ASD) is a neurodevelopmental syndrome known to have a significant but complex genetic etiology. Hundreds of diverse genes have been…”
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Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation by Ziats, Mark N., Comeaux, Mathew S., Yang, Yaping, Scaglia, Fernando, Elsea, Sarah H., Sun, Qin, Beaudet, Arthur L., Schaaf, Christian P.

“…Disorders of carnitine biosynthesis have recently been associated with neurodevelopmental syndromes such as autism spectrum disorder (ASD). A 4‐year‐old male…”
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Sex-biased gene expression in the developing brain: implications for autism spectrum disorders by Ziats, Mark N, Rennert, Owen M

“…Autism spectrum disorders affect significantly more males than females. Understanding sex differences in normal human brain development may provide insight…”
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The Cerebellum in Autism: Pathogenic or an Anatomical Beacon? by Ziats, Mark N., Rennert, Owen M.

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The autistic brain in the context of normal neurodevelopment by Ziats, Mark N, Edmonson, Catherine, Rennert, Owen M

“…The etiology of autism spectrum disorders (ASDs) is complex and largely unclear. Among various lines of inquiry, many have suggested convergence onto…”
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Corrigendum to "Improvement of regressive autism symptoms in a child with TMLHE deficiency following carnitine supplementation" by Ziats, Mark N., Comeaux, Matthew S., Yang, Yaping, Scaglia, Fernando, Elsea, Sarah H., Sun, Qin, Beaudet, Arthur L., Schaaf, Christian P.

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Prevalence of CYP2B6 alleles in malaria-endemic populations of West Africa and Papua New Guinea by MEHLOTRA, Rajeev K, ZIATS, Mark N, BOCKARIE, Moses J, ZIMMERMAN, Peter A

“…Cytochrome P450 2B6 (CYP2B6) is involved in the metabolism of artemisinin drugs, a novel series of antimalarials. Our aim was to analyze the prevalence of the…”
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Identification of differentially expressed microRNAs across the developing human brain by Ziats, M N, Rennert, O M

“…We present a spatio-temporal assessment of microRNA (miRNA) expression throughout early human brain development. We assessed the prefrontal cortex, hippocampus…”
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