Search Results - "ZHUBI, Adrian"
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Characterization of Brain Neurons That Express Enzymes Mediating Neurosteroid Biosynthesis
Published in Proceedings of the National Academy of Sciences - PNAS (26-09-2006)“…Allopregnanolone (ALLO) and tetrahydrodeoxycorticosterone (THDOC) are potent positive allosteric modulators of GABA action at$GABA_{A}$receptors. ALLO and…”
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Epigenetic mechanisms in autism spectrum disorder
Published in International review of neurobiology (2014)“…Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by impaired social interactions, language deficits, as well as restrictive or…”
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Gene expression of methylation cycle and related genes in lymphocytes and brain of patients with schizophrenia and non-psychotic controls
Published in Biomarkers in neuropsychiatry (01-12-2021)“…•Sex influenced the extent to differences in mRNAs in lymphocytes (PBLs) between schizophrenics (CSZ) and controls (NPC). There were differences between in CSZ…”
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Imidazenil and Diazepam Increase Locomotor Activity in Mice Exposed to Protracted Social Isolation
Published in Proceedings of the National Academy of Sciences - PNAS (14-03-2006)“…In cortex and hippocampus, protracted (>4 weeks) social isolation of adult male mice alters the subunit expression of GABA type A receptors ($GABA_{A}-RS$) as…”
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Epigenetic regulation of RELN and GAD1 in the frontal cortex (FC) of autism spectrum disorder (ASD) subjects
Published in International journal of developmental neuroscience (01-11-2017)“…•The RELN and GAD1 mRNA levels were reduced in ASD PFC.•TET 1, 2, and 3 mRNAs were increased in ASD PFC.•There was increased DNMT1 and MECP2 promoter…”
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Selective alpha sub(4) beta sub(2) Nicotinic Acetylcholine Receptor Agonists Target Epigenetic Mechanisms in Cortical GABAergic Neurons
Published in Neuropsychopharmacology (New York, N.Y.) (01-06-2011)“…Nicotine improves cognitive performance and attention in both experimental animals and in human subjects, including patients affected by neuropsychiatric…”
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Selective [alpha]4[beta]2 Nicotinic Acetylcholine Receptor Agonists Target Epigenetic Mechanisms in Cortical GABAergic Neurons
Published in Neuropsychopharmacology (New York, N.Y.) (01-06-2011)“…Nicotine improves cognitive performance and attention in both experimental animals and in human subjects, including patients affected by neuropsychiatric…”
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Selective α4β2 nicotinic acetylcholine receptor agonists target epigenetic mechanisms in cortical GABAergic neurons
Published in Neuropsychopharmacology (New York, N.Y.) (01-06-2011)“…Nicotine improves cognitive performance and attention in both experimental animals and in human subjects, including patients affected by neuropsychiatric…”
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GABAergic promoter hypermethylation as a model to study the neurochemistry of schizophrenia vulnerability
Published in Expert review of neurotherapeutics (01-01-2009)“…The neuronal GABAergic mechanisms that mediate the symptomatic beneficial effects elicited by a combination of antipsychotics with valproate (a histone…”
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Varenicline treatment decreases DNMT1 mRNA expression in lymphocytes of schizophrenic patients who are cigarette smokers
Published in Schizophrenia research (01-06-2010)Get full text
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