Search Results - "ZHU, John Z"
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Penetration of GSK1322322 into Epithelial Lining Fluid and Alveolar Macrophages as Determined by Bronchoalveolar Lavage
Published in Antimicrobial Agents and Chemotherapy (01-01-2014)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Journal Article -
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Tyrosine sulfation: an increasingly recognised post-translational modification of secreted proteins
Published in New biotechnology (01-06-2009)“…The post-translational sulfation of tyrosine residues occurs in numerous secreted and integral membrane proteins and, in many cases, plays a crucial role in…”
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Journal Article -
3
DSCR1 interacts with FMRP and is required for spine morphogenesis and local protein synthesis
Published in The EMBO journal (12-09-2012)“…Most common genetic factors known to cause intellectual disability are Down syndrome and Fragile X syndrome. However, the underlying cellular and molecular…”
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Journal Article -
4
Safety, tolerability, and efficacy of GSK1322322 in the treatment of acute bacterial skin and skin structure infections
Published in Antimicrobial agents and chemotherapy (01-11-2014)“…GSK1322322 represents a new class of antibiotics that targets an essential bacterial enzyme required for protein maturation, peptide deformylase. This…”
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Journal Article -
5
Tyrosine Sulfation Influences the Chemokine Binding Selectivity of Peptides Derived from Chemokine Receptor CCR3
Published in Biochemistry (Easton) (08-03-2011)“…The interactions of chemokines with their G protein-coupled receptors play critical roles in the control of leukocyte trafficking in normal homeostasis and in…”
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Journal Article -
6
Estimating nitrogen exports in response to forest vegetation, age and soil types in two coastal-forested watersheds in British Columbia
Published in Forest ecology and management (05-04-2008)“…This study compared the variability in nitrogen (N) export as a function of (i) vegetation types, (ii) soil types, and (iii) both vegetation and soil types…”
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Journal Article -
7
Regulation of Chemokine Recognition by Site-Specific Tyrosine Sulfation of Receptor Peptides
Published in Chemistry & biology (27-02-2009)“…Sulfation of tyrosine is a common posttranslational modification of secreted proteins that influences numerous physiological and pathological processes…”
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Journal Article -
8
DSCR1 interacts with FMRP and is required for spine morphogenesis and local protein synthesis: Regulatory activity of DSCR1 and FMRP
Published in The EMBO journal (12-09-2012)Get full text
Journal Article -
9
Phase I/II Trial of the MEK1/2 Inhibitor Trametinib (GSK1120212) in Relapsed/Refractory Myeloid Malignancies: Evidence of Activity in Patients with RAS Mutation-Positive Disease
Published in Blood (16-11-2012)“…Abstract 677 Activating mutations of NRAS and KRAS (‘RAS') are found in 10–30% of myeloid malignancies. Evidence of constitutive activation of the…”
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10
Sulfotyrosines impart ligand specificity in a chemokine receptor model system
Published 01-01-2009“…Sulfotyrosines are an integral part of biology; they are found in numerous systems and can augment intermolecular interactions. Chemokine receptors are a…”
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Dissertation -
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Sulfotyrosines impart ligand specificity in a chemokine receptor model system
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Dissertation