Search Results - "ZHIFU SUN"

CrossMap: a versatile tool for coordinate conversion between genome assemblies by Zhao, Hao, Sun, Zhifu, Wang, Jing, Huang, Haojie, Kocher, Jean-Pierre, Wang, Liguo

“…Reference genome assemblies are subject to change and refinement from time to time. Generally, researchers need to convert the results that have been analyzed…”
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Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome by Mars, Ruben A.T., Yang, Yi, Ward, Tonya, Houtti, Mo, Priya, Sambhawa, Lekatz, Heather R., Tang, Xiaojia, Sun, Zhifu, Kalari, Krishna R., Korem, Tal, Bhattarai, Yogesh, Zheng, Tenghao, Bar, Noam, Frost, Gary, Johnson, Abigail J., van Treuren, Will, Han, Shuo, Ordog, Tamas, Grover, Madhusudan, Sonnenburg, Justin, D’Amato, Mauro, Camilleri, Michael, Elinav, Eran, Segal, Eran, Blekhman, Ran, Farrugia, Gianrico, Swann, Jonathan R., Knights, Dan, Kashyap, Purna C.

“…The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. Determining its mechanistic role in disease has been…”
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Characterization of human plasma-derived exosomal RNAs by deep sequencing by Huang, Xiaoyi, Yuan, Tiezheng, Tschannen, Michael, Sun, Zhifu, Jacob, Howard, Du, Meijun, Liang, Meihua, Dittmar, Rachel L, Liu, Yong, Liang, Mingyu, Kohli, Manish, Thibodeau, Stephen N, Boardman, Lisa, Wang, Liang

“…Exosomes, endosome-derived membrane microvesicles, contain specific RNA transcripts that are thought to be involved in cell-cell communication. These RNA…”
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Exosomal miR-1290 and miR-375 as Prognostic Markers in Castration-resistant Prostate Cancer by Huang, Xiaoyi, Yuan, Tiezheng, Liang, Meihua, Du, Meijun, Xia, Shu, Dittmar, Rachel, Wang, Dian, See, William, Costello, Brian A, Quevedo, Fernando, Tan, Winston, Nandy, Debashis, Bevan, Graham H, Longenbach, Sherri, Sun, Zhifu, Lu, Yan, Wang, Tao, Thibodeau, Stephen N, Boardman, Lisa, Kohli, Manish, Wang, Liang

“…Abstract Background Extracellular microRNAs (miRNAs) embedded in circulating exosomes may serves as prognostic biomarkers in cancer. Objective To identify and…”
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Use of FFPE-derived DNA in next generation sequencing: DNA extraction methods by McDonough, Samantha J, Bhagwate, Aditya, Sun, Zhifu, Wang, Chen, Zschunke, Michael, Gorman, Joshua A, Kopp, Karla J, Cunningham, Julie M

“…Archival tissues represent a rich resource for clinical genomic studies, particularly when coupled with comprehensive medical records. Use of these in next…”
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Spectrum of EGFR aberrations and potential clinical implications: insights from integrative pan‐cancer analysis by Liu, Haijing, Zhang, Bo, Sun, Zhifu

“…Background Human epidermal growth factor receptor (EGFR) is an oncogenic gene and one of top targets of precision therapy in lung cancer with EGFR mutations…”
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Pathways Impacted by Genomic Alterations in Pulmonary Carcinoid Tumors by Asiedu, Michael K, Thomas, Jr, Charles F, Dong, Jie, Schulte, Sandra C, Khadka, Prasidda, Sun, Zhifu, Kosari, Farhad, Jen, Jin, Molina, Julian, Vasmatzis, George, Kuang, Ray, Aubry, Marie Christine, Yang, Ping, Wigle, Dennis A

“…Pulmonary carcinoid tumors account for up to 5% of all lung malignancies in adults, comprise 30% of all carcinoid malignancies, and are defined histologically…”
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Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes by Lomberk, Gwen, Blum, Yuna, Nicolle, Rémy, Nair, Asha, Gaonkar, Krutika Satish, Marisa, Laetitia, Mathison, Angela, Sun, Zhifu, Yan, Huihuang, Elarouci, Nabila, Armenoult, Lucile, Ayadi, Mira, Ordog, Tamas, Lee, Jeong-Heon, Oliver, Gavin, Klee, Eric, Moutardier, Vincent, Gayet, Odile, Bian, Benjamin, Duconseil, Pauline, Gilabert, Marine, Bigonnet, Martin, Garcia, Stephane, Turrini, Olivier, Delpero, Jean-Robert, Giovannini, Marc, Grandval, Philippe, Gasmi, Mohamed, Secq, Veronique, De Reyniès, Aurélien, Dusetti, Nelson, Iovanna, Juan, Urrutia, Raul

“…Recent studies have offered ample insight into genome-wide expression patterns to define pancreatic ductal adenocarcinoma (PDAC) subtypes, although there…”
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Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies by Wang, Junjun, Liu, Qingyun, Yuan, Shuai, Xie, Weijia, Liu, Yuan, Xiang, Ying, Wu, Na, Wu, Long, Ma, Xiangyu, Cai, Tongjian, Zhang, Yao, Sun, Zhifu, Li, Yafei

“…More than 1000 candidate-gene association studies on genetic susceptibility to lung cancer have been published over the last two decades but with few…”
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NUCLIZE for quantifying epigenome: generating histone modification data at single-nucleosome resolution using genuine nucleosome positions by Zheng, Daoshan, Trynda, Justyna, Sun, Zhifu, Li, Zhaoyu

“…Defining histone modification at single-nucleosome resolution provides accurate epigenomic information in individual nucleosomes. However, most of histone…”
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Association between ALS and retroviruses: evidence from bioinformatics analysis by Klein, Jon P, Sun, Zhifu, Staff, Nathan P

“…Emerging evidence suggests retroviruses play a role in the pathophysiology of amyotrophic lateral sclerosis (ALS). Specifically, activation of ancient viral…”
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Genetic variants and risk of lung cancer in never smokers: a genome-wide association study by Li, Yafei, PhD, Sheu, Chau-Chyun, MD, Ye, Yuanqing, PhD, de Andrade, Mariza, Prof, Wang, Liang, PhD, Chang, Shen-Chih, PhD, Aubry, Marie C, MD, Aakre, Jeremiah A, BS, Allen, Mark S, Prof, Chen, Feng, PhD, Cunningham, Julie M, PhD, Deschamps, Claude, Prof, Jiang, Ruoxiang, BS, Lin, Jie, PhD, Marks, Randolph S, MD, Pankratz, V Shane, PhD, Su, Li, BS, Li, Yan, MD, Sun, Zhifu, MD, Tang, Hui, PhD, Vasmatzis, George, PhD, Harris, Curtis C, MD, Spitz, Margaret R, Prof, Jen, Jin, PhD, Wang, Renyi, MPH, Zhang, Zuo-Feng, Prof, Christiani, David C, Prof, Wu, Xifeng, Prof, Yang, Ping, Dr, Prof

“…Summary Background Lung cancer in individuals who have never smoked tobacco products is an increasing medical and public-health issue. We aimed to unravel the…”
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Base resolution methylome profiling: considerations in platform selection, data preprocessing and analysis by Sun, Zhifu, Cunningham, Julie, Slager, Susan, Kocher, Jean-Pierre

“…Bisulfite treatment-based methylation microarray (mainly Illumina 450K Infinium array) and next-generation sequencing (reduced representation bisulfite…”
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New DNA Methylation Markers for Pancreatic Cancer: Discovery, Tissue Validation, and Pilot Testing in Pancreatic Juice by Kisiel, John B, Raimondo, Massimo, Taylor, William R, Yab, Tracy C, Mahoney, Douglas W, Sun, Zhifu, Middha, Sumit, Baheti, Saurabh, Zou, Hongzhi, Smyrk, Thomas C, Boardman, Lisa A, Petersen, Gloria M, Ahlquist, David A

“…Discriminant markers for pancreatic cancer detection are needed. We sought to identify and validate methylated DNA markers for pancreatic cancer using…”
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Apatinib Reverses Paclitaxel-resistant Lung Cancer Cells (A549) Through Blocking the Function of ABCB1 Transporter by ZHANG, QUNCHENG, SONG, YONGAN, CHENG, XIANGSONG, XU, ZHIWEI, MATTHEW, OLAJUYIN AYOBAMI, WANG, JIA, SUN, ZHIFU, ZHANG, XIAOJU

“…Background/Aim: Multidrug resistance (MDR) is often associated with overexpression of P-glycoprotein (ABCB1) in cancer cells. Apatinib is a novel Vascular…”
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Transcriptome Profiling of Acquired Gefitinib Resistant Lung Cancer Cells Reveals Dramatically Changed Transcription Programs and New Treatment Targets by Wei, Nan, Song, Yong'an, Zhang, Fan, Sun, Zhifu, Zhang, Xiaoju

“…Background: Targeted therapy for lung cancer with epidermal growth factor receptor ( EGFR ) mutations with tyrosine kinase inhibitors (TKIs) represents one of…”
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RNF20 and RNF40 regulate vitamin D receptor-dependent signaling in inflammatory bowel disease by Kosinsky, Robyn Laura, Zerche, Maria, Kutschat, Ana Patricia, Nair, Asha, Ye, Zhenqing, Saul, Dominik, von Heesen, Maximilian, Friton, Jessica J., Schwarzer, Ana Carolina, Paglilla, Nadia, Sheikh, Shehzad Z., Wegwitz, Florian, Sun, Zhifu, Ghadimi, Michael, Newberry, Rodney D., Sartor, R. Balfour, Faubion, William A., Johnsen, Steven A.

“…Despite the identification of several genetic factors linked to increased susceptibility to inflammatory bowel disease (IBD), underlying molecular mechanisms…”
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A genetic cell context-dependent role for ZEB1 in lung cancer by Zhang, Ting, Guo, Lixia, Creighton, Chad J., Lu, Qiang, Gibbons, Don L., Yi, Eunhee S., Deng, Bo, Molina, Julian R., Sun, Zhifu, Yang, Ping, Yang, Yanan

“…The Zinc-finger E-box-binding Homeobox-1 (ZEB1) is a transcription factor that promotes epithelial–mesenchymal transition (EMT) and acts as an oncogene in KRAS…”
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Chronic Caloric Restriction Preserves Mitochondrial Function in Senescence without Increasing Mitochondrial Biogenesis by Lanza, Ian R., Zabielski, Piotrek, Klaus, Katherine A., Morse, Dawn M., Heppelmann, Carrie J., Bergen, H. Robert, Dasari, Surendra, Walrand, Stephane, Short, Kevin R., Johnson, Matthew L., Robinson, Matthew M., Schimke, Jill M., Jakaitis, Daniel R., Asmann, Yan W., Sun, Zhifu, Nair, K. Sreekumaran

“…Caloric restriction (CR) mitigates many detrimental effects of aging and prolongs life span. CR has been suggested to increase mitochondrial biogenesis,…”
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Folate receptor-α (FOLR1) expression and function in triple negative tumors by Necela, Brian M, Crozier, Jennifer A, Andorfer, Cathy A, Lewis-Tuffin, Laura, Kachergus, Jennifer M, Geiger, Xochiquetzal J, Kalari, Krishna R, Serie, Daniel J, Sun, Zhifu, Moreno-Aspitia, Alvaro, Aspita, Alvaro Moreno, O'Shannessy, Daniel J, Maltzman, Julia D, McCullough, Ann E, Pockaj, Barbara A, Cunliffe, Heather E, Ballman, Karla V, Thompson, E Aubrey, Perez, Edith A

“…Folate receptor alpha (FOLR1) has been identified as a potential prognostic and therapeutic target in a number of cancers. A correlation has been shown between…”
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