Search Results - "ZHENGWEI DONG"
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Genomic landscape and its correlations with tumor mutational burden, PD-L1 expression, and immune cells infiltration in Chinese lung squamous cell carcinoma
Published in Journal of hematology and oncology (12-07-2019)“…To depict the genomic landscape of Chinese early-stage lung squamous cell carcinoma (LUSC) and investigate its correlation with tumor mutation burden (TMB),…”
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2
Diffuse intrapulmonary mesothelioma mimicking pulmonary lepidic adenocarcinoma: a rare case report and review of the literature
Published in Diagnostic pathology (16-05-2023)“…Mesothelioma, with various clinical manifestations, radiological features, and histomorphological types, can be divided into epithelioid, sarcomatoid, and…”
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3
Clinical Significance of Dual-Block Elastic Stain Evaluating Visceral Pleural Invasion in Peripheral Non-Small Cell Lung Cancer
Published in International journal of surgical pathology (01-04-2023)“…Visceral pleural invasion (VPI) is a critical component in the staging of peripheral non-small cell lung carcinoma (NSCLC). We aim to investigate whether…”
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4
Cribriform growth pattern in lung adenocarcinoma: More aggressive and poorer prognosis than acinar growth pattern
Published in Lung cancer (Amsterdam, Netherlands) (01-09-2020)“…•Cribriform growth pattern is more aggressive than acinar growth pattern in lung adenocarcinoma.•Cribriform component present were associated with increased…”
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5
Translating the Therapeutic Potential of AZD4547 in FGFR1-Amplified Non―Small Cell Lung Cancer through the Use of Patient-Derived Tumor Xenograft Models
Published in Clinical cancer research (15-12-2012)“…To investigate the incidence of FGFR1 amplification in Chinese non-small cell lung cancer (NSCLC) and to preclinically test the hypothesis that the novel,…”
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6
Contrast-enhanced ultrasound guided pleural biopsy improves diagnostic confidence for pleural based lesions: a 3-year prospective study
Published in BMC pulmonary medicine (12-07-2021)“…Abstract Objective To evaluate the accuracy and safety of contrast-enhanced ultrasound (CEUS) guided biopsy in the diagnosis of radiologically determined…”
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7
Improving differential diagnosis of pulmonary large cell neuroendocrine carcinoma and small cell lung cancer via a transcriptomic, biological pathway-based machine learning model
Published in Translational oncology (01-12-2021)“…•A transcriptomic, biological pathway-based machine learning model was constructed.•This classification model can predict LCNEC from borderline samples.•The…”
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8
Platelets Direct Monocyte Differentiation Into Epithelioid-Like Multinucleated Giant Foam Cells With Suppressive Capacity Upon Mycobacterial Stimulation
Published in The Journal of infectious diseases (01-12-2014)“…Background. Epithelioid, foam, and multinucleated giant cells (MNGCs) are characteristics of tuberculosis granulomas, yet the precise genesis and functions of…”
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Paradoxical development of pleural-based masses in patients with pleural tuberculosis during treatment: a clinical observational study in China
Published in BMC pulmonary medicine (04-04-2022)“…To explored the clinical, pathological, and bacteriological characteristics of pleural-based masses occurred during anti-tuberculosis (TB) treatment in…”
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10
Prevalence and Prognostic Role of BRCA1/2 Variants in Unselected Chinese Breast Cancer Patients
Published in PloS one (03-06-2016)“…The prevalence of BRCA1/2 variants in Chinese breast cancer patients varies among studies. Germline or somatic BRCA1/2 mutations are associated with…”
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11
Evaluation of cytology in lung cancer diagnosis based on EBUS-TBNA
Published in Journal of cytology (01-04-2017)“…Endobronchial ultrasound (EBUS) is a relatively new modality that can be used to guide transbronchial needle aspiration (TBNA) of mediastinal lymph nodes. At…”
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Recurrent amplification of MYC and TNFRSF11B in 8q24 is associated with poor survival in patients with gastric cancer
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-01-2016)“…Background Gastric cancer (GC) is an aggressive malignancy whose mechanisms of development and progression are poorly understood. The identification of…”
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13
Sublobectomy is a safe alternative for localized cavitary pulmonary tuberculosis
Published in Journal of cardiothoracic surgery (17-03-2021)“…Surgical resection plays an essential role in the treatment of Pulmonary Tuberculosis (PTB). There are few reports comparing lobectomy and sublobectomy for…”
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14
Heat shock does not induce γH2AX foci formation but protects cells from N-methyl- N′-nitro- N-nitrosoguanidine-induced genotoxicity
Published in Mutation research. Genetic toxicology and environmental mutagenesis (20-04-2007)“…The involvement of DNA damage in heat shock-induced cell death remains controversial. To investigate whether heat shock can induce DNA damage, we tested the…”
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15
Highly Sensitive Droplet Digital PCR Method for Detection of EGFR -Activating Mutations in Plasma Cell–Free DNA from Patients with Advanced Non–Small Cell Lung Cancer
Published in The Journal of molecular diagnostics : JMD (01-05-2015)“…Epidermal growth factor receptor ( EGFR ) mutation testing in plasma cell-free DNA from lung cancer patients is an emerging clinical tool. However, compared…”
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16
Metformin attenuates atherosclerosis and plaque vulnerability by upregulating KLF2-mediated autophagy in apoE−/- mice
Published in Biochemical and biophysical research communications (11-06-2021)“…Atherosclerosis is a chronic lipid disfunction and inflammatory disease, which is characterized with enriched foam cells and necrotic core underneath the…”
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Predictive value of oncogenic driver subtype, programmed death‐1 ligand (PD‐L1) score, and smoking status on the efficacy of PD‐1/PD‐L1 inhibitors in patients with oncogene‐driven non–small cell lung cancer
Published in Cancer (01-04-2019)“…Background This multicenter, retrospective study explored the value of oncogene driver subtype, programmed death‐1 ligand (PD‐L1) status, and smoking status…”
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18
Improving differential diagnosis of pulmonary large cell neuroendocrine carcinoma (LCNEC) and small cell lung cancer via a transcriptomic, biological pathway-based ridge regression model
Published in Journal of clinical oncology (20-05-2021)“…Abstract only 3065 Background: In clinics, it can be challenging to make correct diagnosis of LCNEC, Small cell lung cancer (SCLC), if tissues, like needle…”
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Early Identification of Fungal and Mycobacterium Infections in Pulmonary Granulomas Using Metagenomic Next-Generation Sequencing on Formalin fixation and paraffin embedding tissue
Published in Expert review of molecular diagnostics (03-04-2022)“…The purpose of the study is to assess the etiology detection ability of Metagenomic Next-Generation Sequencing (mNGS) on formalin fixation and paraffin…”
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Intraoperatively measured tumor size and frozen section results should be considered jointly to predict the final pathology for lung adenocarcinoma
Published in Modern pathology (01-09-2018)“…Invasive adenocarcinoma intraoperatively misdiagnosed as adenocarcinoma in situ or minimally invasive adenocarcinoma is more likely to undergo potentially…”
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