Search Results - "ZHENGFANG YI"

Copper Silicate Hollow Microspheres-Incorporated Scaffolds for Chemo-Photothermal Therapy of Melanoma and Tissue Healing by Yu, Qingqing, Han, Yiming, Wang, Xiaocheng, Qin, Chen, Zhai, Dong, Yi, Zhengfang, Chang, Jiang, Xiao, Yin, Wu, Chengtie

“…The treatment of melanoma requires complete removal of tumor cells and simultaneous tissue regeneration of tumor-initiated cutaneous defects. Herein, copper…”
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Preparation of copper-containing bioactive glass/eggshell membrane nanocomposites for improving angiogenesis, antibacterial activity and wound healing by Li, Jinyan, Zhai, Dong, Lv, Fang, Yu, Qingqing, Ma, Hongshi, Yin, Jinbo, Yi, Zhengfang, Liu, Mingyao, Chang, Jiang, Wu, Chengtie

“…Copper-containing bioactive glass/eggshell membrane nanocomposites with uniform BG nanocoatings (thickness: 40nm) improving antibacterial activity, angiogenic…”
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Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression by Chen, Sujun, Zhu, Guanghui, Yang, Yue, Wang, Fubo, Xiao, Yu-Tian, Zhang, Na, Bian, Xiaojie, Zhu, Yasheng, Yu, Yongwei, Liu, Fei, Dong, Keqin, Mariscal, Javier, Liu, Yin, Soares, Fraser, Loo Yau, Helen, Zhang, Bo, Chen, Weidong, Wang, Chao, Chen, Dai, Guo, Qinghua, Yi, Zhengfang, Liu, Mingyao, Fraser, Michael, De Carvalho, Daniel D., Boutros, Paul C., Di Vizio, Dolores, Jiang, Zhou, van der Kwast, Theodorus, Berlin, Alejandro, Wu, Song, Wang, Jianhua, He, Housheng Hansen, Ren, Shancheng

“…Prostate cancer shows remarkable clinical heterogeneity, which manifests in spatial and clonal genomic diversity. By contrast, the transcriptomic heterogeneity…”
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Targeting STAT3 by a small molecule suppresses pancreatic cancer progression by Chen, Huang, Bian, Aiwu, Yang, Lian-fang, Yin, Xuan, Wang, Jie, Ti, Chaowen, Miao, Ying, Peng, Shihong, Xu, Shifen, Liu, Mingyao, Qiu, Wen-Wei, Yi, Zhengfang

“…Pancreatic cancer is lethal in over 90% of cases since it is resistant to current therapeutic strategies. The key role of STAT3 in promoting pancreatic cancer…”
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Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer by He, Yundong, Peng, Shihong, Wang, Jinhua, Chen, Huang, Cong, Xiaonan, Chen, Ang, Hu, Meichun, Qin, Min, Wu, Haigang, Gao, Shuman, Wang, Liguo, Wang, Xin, Yi, Zhengfang, Liu, Mingyao

“…Androgen receptor (AR) antagonist MDV3100 is the first therapeutic approach in treating castration-resistant prostate cancer (CRPC), but tumours frequently…”
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Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway by XIUFENG PANG, ZHENGFANG YI, JING ZHANG, BINBIN LU, BOKYUNG SUNG, WEIJING QU, AGGARWAL, Bharat B, MINGYAO LIU

“…Understanding the molecular basis and target of traditional medicine is critical for drug development. Celastrol, derived from Trypterygium wilfordii Hook F…”
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A small molecule targeting myoferlin exerts promising anti-tumor effects on breast cancer by Zhang, Tao, Li, Jingjie, He, Yuan, Yang, Feifei, Hao, Yun, Jin, Wangrui, Wu, Jing, Sun, Zhenliang, Li, Yunqi, Chen, Yihua, Yi, Zhengfang, Liu, Mingyao

“…Breast cancer is one of the most lethal cancers in women when it reaches the metastatic stage. Here, we screen a library of small molecules for inhibitors of…”
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Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer by Chen, Jing, Wang, Jieqiong, Lin, Lei, He, Lijun, Wu, Yuanyuan, Zhang, Li, Yi, Zhengfang, Chen, Yihua, Pang, Xiufeng, Liu, Mingyao

“…STAT3 has been strongly implicated in human malignancies, and constitutive activation of STAT3 serves a crucial role in cell survival, angiogenesis, immune…”
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Hispidulin, a small flavonoid molecule, suppresses the angiogenesis and growth of human pancreatic cancer by targeting vascular endothelial growth factor receptor 2‐mediated PI3K/Akt/mTOR signaling pathway by He, Lijun, Wu, Yuanyuan, Lin, Lei, Wang, Jieqiong, Wu, Yougen, Chen, Yihua, Yi, Zhengfang, Liu, Mingyao, Pang, Xiufeng

“…Hispidulin, an active component from Artemisia vestita, a traditional Tibetan medicinal plant, has been shown to possess anti‐inflammatory and anti‐oxidative…”
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Acetyl-11 -Keto-β-Boswellic Acid Inhibits Prostate Tumor Growth by Suppressing Vascular Endothelial Growth Factor Receptor 2-Mediated Angiogenesis by XIUFENG PANG, ZHENGFANG YI, XIAOLI ZHANG, BOKYUNG SUNG, WEIJING QU, XIAOYUAN LIAN, AGGARWAL, Bharat B, MINGYAO LIU

“…The role of angiogenesis in tumor growth and metastasis is well established. Identification of a small molecule that blocks tumor angiogenesis and is safe and…”
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Lycorine inhibits breast cancer growth and metastasis via inducing apoptosis and blocking Src/FAK-involved pathway by Ying, Xuexiang, Huang, Anling, Xing, Yajing, Lan, Liping, Yi, Zhengfang, He, Pingqing

“…Breast cancer is the most commonly diagnosed cancer type worldwide among women and more than 90% of patients die from tumor metastasis. Lycorine, a natural…”
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Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways by Yi, Tingfang, Cho, Sung-Gook, Yi, Zhengfang, Pang, Xiufeng, Rodriguez, Melissa, Wang, Ying, Sethi, Gautam, Aggarwal, Bharat B, Liu, Mingyao

“…Thymoquinone, a component derived from the medial plant Nigella sativa , has been used for medical purposes for more than 2,000 years. Recent studies reported…”
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Lycorine is a novel inhibitor of the growth and metastasis of hormone-refractory prostate cancer by Hu, Meichun, Peng, Shihong, He, Yundong, Qin, Min, Cong, Xiaonan, Xing, Yajing, Liu, Mingyao, Yi, Zhengfang

“…Lycorine, a natural alkaloid extracted from the Amaryllidaceae plant family, has been reported to exhibit a wide range of physiological effects, including the…”
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The synthesis and antistaphylococcal activity of 9, 13-disubstituted berberine derivatives by Wang, Jing, Yang, Teng, Chen, Huang, Xu, Yun-Nan, Yu, Li-Fang, Liu, Ting, Tang, Jie, Yi, Zhengfang, Yang, Cai-Guang, Xue, Wei, Yang, Fan

“…A series of novel 9, 13-disubstituted berberine derivatives have been synthesized and evaluated for the antibacterial activities against Staphylococcus aureus,…”
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Usnic acid inhibits breast tumor angiogenesis and growth by suppressing VEGFR2-mediated AKT and ERK1/2 signaling pathways by Song, Yajuan, Dai, Fujun, Zhai, Dong, Dong, Yanmin, Zhang, Jing, Lu, Binbin, Luo, Jian, Liu, Mingyao, Yi, Zhengfang

“…Tumor growth depends on angiogenesis and inducing angiogenesis is one of the most important hallmarks in the cancer development. Treatment with small molecules…”
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A small molecule BCL6 inhibitor as chemosensitizers in acute myeloid leukemia by Zhang, Lin, Wu, Min, Guo, Weikai, Zhu, Shuangshuang, Li, Shen, Lv, Shiyi, Li, Yan, Liu, Layang, Xing, Yajing, Chen, Huang, Liu, Mingyao, Peng, Shihong, Chen, Yihua, Yi, Zhengfang

“…BCL6 is a transcriptional repressor that regulates multiple genes involved in immune cell differentiation, DNA damage repair, cell cycle, and apoptosis, and is…”
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Gambogic Acid Inhibits Angiogenesis and Prostate Tumor Growth by Suppressing Vascular Endothelial Growth Factor Receptor 2 Signaling by TINGFANG YI, ZHENGFANG YI, CHO, Sung-Gook, JIAN LUO, PANDEY, Manoj K, AGGARWAL, Bharat B, MINGYAO LIU

“…Gambogic acid (GA), the main active compound of Gamboge hanburyi, has been previously reported to activate apoptosis in many types of cancer cell lines by…”
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Oridonin inhibits tumor growth and metastasis through anti-angiogenesis by blocking the Notch signaling by Dong, Yanmin, Zhang, Tao, Li, Jingjie, Deng, Huayun, Song, Yajuan, Zhai, Dong, Peng, Yi, Lu, Xiaoling, Liu, Mingyao, Zhao, Yongxiang, Yi, Zhengfang

“…While significant progress has been made in understanding the anti-inflammatory and anti-proliferative effects of the natural diterpenoid component Oridonin on…”
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Ailanthone: a new potential drug for castration-resistant prostate cancer by Peng, Shihong, Yi, Zhengfang, Liu, Mingyao

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Cucurbitacin E inhibits breast tumor metastasis by suppressing cell migration and invasion by Zhang, Tao, Li, Jingjie, Dong, Yanmin, Zhai, Dong, Lai, Li, Dai, Fujun, Deng, Huayun, Chen, Yihua, Liu, Mingyao, Yi, Zhengfang

“…Tumor metastasis is the main cause of cancer-related deaths of patients. Breast cancer is highly malignant with considerable metastatic potential, which urges…”
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