Search Results - "ZHENFENG HONG"

Cofilin Inhibition by Limk1 Reduces Rod Formation and Cell Apoptosis after Ischemic Stroke by Chen, Bin, Lin, Wanqing, Qi, Wan, Li, Shibin, Hong, Zhenfeng, Zhao, Hongjia

“…•ATP depletion induced cofilin rod formation and neuronal apoptosis.•Infarct volume increased from 2 h to 24 h, then became stable from 24 h to 7 d after…”
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Ursolic acid inhibits colorectal cancer angiogenesis through suppression of multiple signaling pathways by Lin, Jiumao, Chen, Youqin, Wei, Lihui, Hong, Zhenfeng, Sferra, Thomas J, Peng, Jun

“…Angiogenesis plays a critical role in the development of solid tumors by supplying nutrients and oxygen to support continuous growth of tumor as well as…”
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Hedyotis diffusa Willd inhibits colorectal cancer growth in vivo via inhibition of STAT3 signaling pathway by Cai, Qiaoyan, Lin, Jiumao, Wei, Lihui, Zhang, Ling, Wang, Lili, Zhan, Youzhi, Zeng, Jianwei, Xu, Wei, Shen, Aling, Hong, Zhenfeng, Peng, Jun

“…Signal Transducer and Activator of Transcription 3 (STAT3), a common oncogenic mediator, is constitutively activated in many types of human cancers; therefore…”
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Hedyotis Diffusa Willd extract induces apoptosis via activation of the mitochondrion-dependent pathway in human colon carcinoma cells by JIUMAO LIN, YOUQIN CHEN, LIHUI WEI, XUZHEN CHEN, WEI XU, ZHENFENG HONG, SFERRA, Thomas J, JUN PENG

“…Hedyotis Diffusa Willd has been used as a major component in several Chinese medicine formulations for the clinical treatment of colorectal cancer. However,…”
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Qianliening Capsule Promotes Mitochondrial Pathway Mediated the Apoptosis of Benign Prostatic Hyperplasia Epithelial-1 Cells by Regulating the miRNA-181a by Zhou, Jianheng, Zhong, Xiaoyong, Lin, Jiumao, Hong, Zhenfeng

“…Our previous studies reported that Qianliening capsule (QC) has a significant therapeutic effect on BPH. Therefore, we investigated the effect QC on apoptosis…”
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Pien Tze Huang inhibits tumor cell proliferation and promotes apoptosis via suppressing the STAT3 pathway in a colorectal cancer mouse model by QUNCHUAN ZHUANG, FEI HONG, ALING SHEN, LIANGPU ZHENG, JIANWEI ZENG, WEI LIN, YOUQIN CHEN, SFERRA, Thomas J, ZHENFENG HONG, JUN PENG

“…Signal transducer and activator of transcription 3 (STAT3) plays a critical role in cell survival and proliferation. Constitutive activation of STAT3 is…”
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THE HERBAL MIXTURE XIAO-CHAI-HU TANG (XCHT) INDUCES APOPTOSIS OF HUMAN HEPATOCELLULAR CARCINOMA HUH7 CELLS IN VITRO AND IN VIVO by Zhao, Jinyan, Liu, Liya, Zhang, Yuchen, Wan, Yun, Hong, Zhenfeng

“…Background: Xiao-Chai-Hu Tang (XCHT) is an extract of seven herbs with anticancer properties, but its mechanism of action is unknown. In this study, we…”
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Pien Tze Huang suppresses IL-6-inducible STAT3 activation in human colon carcinoma cells through induction of SOCS3 by SHEN, ALING, CHEN, YOUQIN, HONG, FEI, LIN, JIUMAO, WEI, LIHUI, HONG, ZHENFENG, SFERRA, THOMAS J, PENG, JUN

“…IL-6/STAT3 is one of the most critical cellular signal transduction pathways known to malfunction in colorectal cancer (CRC). As a target gene of signal…”
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Rapid simultaneous determination of twelve major components in Pien Tze Huang by ultra-performance liquid chromatography coupled with triple quadrupole mass spectrometry by Huang, Mingqing, Zhao, Haiyu, Xu, Wei, Chu, Kedan, Hong, Zhenfeng, Peng, Jun, Chen, Lidian

“…An efficient method using ultra‐performance LC coupled with triple quadrupole MS was developed for the rapid determination of 12 major active components in…”
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Anti-proliferative effects of qianliening capsules on prostatic hyperplasia in vitro and in vivo by ZHONG, XIAOYONG, LIN, JIUMAO, ZHOU, JIANHENG, XU, WEI, HONG, ZHENFENG

“…Previous studies by our group showed that Qianliening capsules (QC), a clinically proven effective traditional Chinese formulation that has long been used in…”
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Hepatoprotection in a Rat Model of Acute Liver Damage Through Inhibition of CY2E1 Activity by Total Alkaloids Extracted From Rubus alceifolius Poir by Lin, Jiumao, Zhao, Jinyan, Li, Tianjiao, Zhou, Jianheng, Hu, Juan, Hong, Zhenfeng

“…We aimed to examine the effect of an alkaloid extract of the roots of Rubus alceifolius Poir on liver damage and cytochrome enzymes, and underlying mechanism…”
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Hepatoprotective effects of Rubus aleaefolius Poir. and identification of its active constituents by Hong, Zhenfeng, Chen, Wang, Zhao, Jinyan, Wu, Zhisheng, Zhou, JianHeng, Li, Tianjiao, Hu, Juan

“…The hepatoprotective effects of the most promising extract of Rubus aleaefolius Poir. one sterol and five triterpenoid constituents have been isolated…”
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Electro-acupuncture at points of Zusanli and Quchi exerts anti-apoptotic effect through the modulation of PI3K/Akt signaling pathway by Xue, Xiehua, You, Yongmei, Tao, Jing, Ye, Xiaoqian, Huang, Jia, Yang, Shanli, Lin, Zhicheng, Hong, Zhenfeng, Peng, Jun, Chen, Lidian

“…•LY294002 is used to investigate the neuroprotective mechanism of EA.•Intracerebroventricularly injected LY294002 depend on stereotaxic apparatus.•EA…”
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Pien Tze Huang Gan Bao attenuates carbon tetrachloride‑induced hepatocyte apoptosis in rats, associated with suppression of p53 activation and oxidative stress by Zhao, Jinyan, Zhang, Yuchen, Wan, Yun, Hu, Haixia, Hong, Zhenfeng

“…Pien Tze Huang Gan Bao (PZH‑GB), a traditional Chinese medicine, has been used for thousands of years as a protective remedy effective against liver injury…”
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Scutellaria barbata D. Don inhibits tumor angiogenesis via suppression of Hedgehog pathway in a mouse model of colorectal cancer by Wei, Lihui, Lin, Jiumao, Xu, Wei, Cai, Qiaoyan, Shen, Aling, Hong, Zhenfeng, Peng, Jun

“…Angiogenesis, which plays a critical role during tumor development, is tightly regulated by the Sonic Hedgehog (SHH) pathway, which has been known to…”
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Ethanol extract of Antrodia camphorata inhibits proliferation of HCT-8 human colorectal cancer cells by arresting cell cycle progression and inducing apoptosis by Wang, Gong, Wan, Yun, Zhao, Jinyan, Hong, Zhenfeng

“…Antrodia camphorata (AC) is well known in Taiwan as a traditional Chinese medicine, with a long history of use in treating cancer and inflammation. Previous…”
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Hedyotis diffusa Willd extract suppresses Sonic hedgehog signaling leading to the inhibition of colorectal cancer angiogenesis by LIN, JIUMAO, WEI, LIHUI, SHEN, ALING, CAI, QIAOYAN, XU, WEI, LI, HUANG, ZHAN, YOUZHI, HONG, ZHENFENG, PENG, JUN

“…Sonic hedgehog (SHH) signaling pathway promotes the process of angiogenesis, contributing to the growth and progression of many human malignancies including…”
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Pien Tze Huang Gan Bao ameliorates carbon tetrachloride-induced hepatic injury, oxidative stress and inflammation in rats by Zhao, Jinyan, Hu, Haixia, Wan, Yun, Zhang, Yuchen, Zheng, Liangpu, Hong, Zhenfeng

“…Liver damage results from a variety of insults, including hepatitis and chemical toxicity from alcohol, drugs and other toxins. The present study evaluated the…”
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Ursolic acid promotes colorectal cancer cell apoptosis and inhibits cell proliferation via modulation of multiple signaling pathways by LIN, JIUMAO, CHEN, YOUQIN, WEI, LIHUI, SHEN, ALING, SFERRA, THOMAS J, HONG, ZHENFENG, PENG, JUN

“…The development of colorectal cancer (CRC) is strongly correlated with the aberrant activation of multiple intracellular signaling transduction cascades…”
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Electroacupuncture enhances hippocampal NSCs proliferation in cerebral ischemia-reperfusion injured rats via activation of notch signaling pathway by Tao, Jing, Chen, Bin, Gao, Yanling, Yang, Shanli, Huang, Jia, Jiang, Xin, Wu, Yayin, Peng, Jun, Hong, Zhenfeng, Chen, Lidian

“…The purpose of this study was to investigate the mechanisms by which electroacupuncture (EA) enhances hippocampal neural stem cells (NSCs) proliferation in…”
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