Search Results - "ZHEN, J"
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Bosniak Classification of Cystic Renal Masses, Version 2019: An Update Proposal and Needs Assessment
Published in Radiology (01-08-2019)“…Cystic renal cell carcinoma (RCC) is almost certainly overdiagnosed and overtreated. Efforts to diagnose and treat RCC at a curable stage result in many benign…”
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Covalently circularized nanodiscs for studying membrane proteins and viral entry
Published in Nature methods (01-01-2017)“…Membrane proteins can be stabilized in a native-like setting using lipid-bilayer-based nanodiscs encircled by a membrane scaffold protein. Covalently…”
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Abbreviated MRI Protocols for the Abdomen
Published in Radiographics (01-05-2019)“…Technical advances in MRI have improved image quality and have led to expanding clinical indications for its use. However, long examination and interpretation…”
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Cryo-EM structure of an activated GPCR–G protein complex in lipid nanodiscs
Published in Nature structural & molecular biology (01-03-2021)“…G-protein-coupled receptors (GPCRs) are the largest superfamily of transmembrane proteins and the targets of over 30% of currently marketed pharmaceuticals…”
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5
Viruses inhibit TIR gcADPR signalling to overcome bacterial defence
Published in Nature (London) (10-11-2022)“…The Toll/interleukin-1 receptor (TIR) domain is a key component of immune receptors that identify pathogen invasion in bacteria, plants and animals 1 – 3 . In…”
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Opportunities for new CT contrast agents to maximize the diagnostic potential of emerging spectral CT technologies
Published in Advanced drug delivery reviews (01-04-2017)“…The introduction of spectral CT imaging in the form of fast clinical dual-energy CT enabled contrast material to be differentiated from other radiodense…”
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Crustal and uppermost mantle S velocity structure under Hi-CLIMB seismic array in central Tibetan Plateau from joint inversion of surface wave dispersion and receiver function data
Published in Tectonophysics (22-01-2013)“…Trade-off between the depth of an interface and the average velocity above the interface is well known in receiver function inversion. To resolve model…”
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CT and MRI of small renal masses
Published in British journal of radiology (01-07-2018)“…Small renal masses are increasingly detected incidentally at imaging. They vary widely in histology and aggressiveness, and include benign renal tumors and…”
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Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix
Published in The Journal of clinical investigation (01-09-2020)“…Desmoplasia describes the deposition of extensive extracellular matrix and defines primary pancreatic ductal adenocarcinoma (PDA). The acellular component of…”
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10
The αβ T Cell Receptor Is an Anisotropic Mechanosensor
Published in The Journal of biological chemistry (06-11-2009)“…Thymus-derived lymphocytes protect mammalian hosts against virus- or cancer-related cellular alterations through immune surveillance, eliminating diseased…”
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11
Protocol Optimization for Renal Mass Detection and Characterization
Published in The Radiologic clinics of North America (01-09-2020)“…Renal masses increasingly are found incidentally, largely due to the frequent use of medical imaging. Computed tomography (CT) and MR imaging are mainstays for…”
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Dynamic T 2 relaxometry of hyperpolarized [1- 13 C]pyruvate MRI in the human brain and kidneys
Published in Magnetic resonance in medicine (01-03-2024)“…This study aimed to quantify for hyperpolarized [1- C]pyruvate and metabolites in the healthy human brain and renal cell carcinoma (RCC) patients at 3 T…”
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13
Joint inversion for crustal and Pn velocities and Moho depth in Eastern Margin of the Tibetan Plateau
Published in Tectonophysics (20-08-2010)“…A classical problem in seismic tomography is the trade-off between a discontinuity location and the velocity of the medium. For that reason, crustal tomography…”
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14
Improved Sensitivity and Reader Confidence in CT Colonography Using Dual-Layer Spectral CT: A Phantom Study
Published in Radiology (01-10-2020)“…Background Limited cathartic preparations for CT colonography with fecal tagging can improve patient comfort but may result in nondiagnostic examinations from…”
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15
Initial Experience of Metabolic Imaging With Hyperpolarized [1- 13 C]pyruvate MRI in Kidney Transplant Patients
Published in Journal of magnetic resonance imaging (06-09-2024)“…Kidney transplant is the treatment of choice for patients with end-stage renal disease. Early detection of allograft injury is important to delay or prevent…”
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Consensus-based technical recommendations for clinical translation of renal BOLD MRI
Published in Magma (New York, N.Y.) (01-02-2020)“…Harmonization of acquisition and analysis protocols is an important step in the validation of BOLD MRI as a renal biomarker. This harmonization initiative…”
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17
Characterization of the novel HLA-A02:431 allele identified in a Chinese Han individual
Published in HLA (01-02-2016)“…HLA‐A*02:431 differs from the closest allele HLA‐A*02:03:01 by a nonsynonymous mutation at nucleotide 317 in exon 2…”
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Dynamic T2 relaxometry of hyperpolarized [1‐13C]pyruvate MRI in the human brain and kidneys
Published in Magnetic resonance in medicine (01-03-2024)“…Purpose This study aimed to quantify T2*$$ {T}_2^{\ast } $$ for hyperpolarized [1‐13C]pyruvate and metabolites in the healthy human brain and renal cell…”
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Bowel Peristalsis Artifact on Dual-Energy CT: In Vitro Study on the Influence of Different Dual-Energy CT Platforms and Enteric Contrast Agents
Published in American journal of roentgenology (1976) (01-02-2022)“… The value of dual-energy CT (DECT) for bowel wall assessment is increasingly recognized. Although technical improvements reduce peristalsis artifact in…”
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Cross-Metathesis Approach to the Tricyclic Marine Alkaloids (−)-Fasicularin and (−)-Lepadiformine A
Published in Journal of organic chemistry (18-08-2017)“…A cross-metathesis protocol has been developed to provide facile access to highly hindered trisubstituted α-branched olefins, which when coupled with a…”
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