Search Results - "ZEQUAN YANG"

Smooth muscle phenotypic modulation is an early event in aortic aneurysms by Ailawadi, Gorav, MD, Moehle, Christopher W., BS, Pei, Hong, MD, Walton, Sandra P., BS, Yang, Zequan, MD, PhD, Kron, Irving L., MD, Lau, Christine L., MD, Owens, Gary K., PhD

“…Objectives Vascular smooth muscle cells can undergo profound changes in phenotype, defined by coordinated repression of smooth muscle cell marker genes and…”
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Stimulation of the Beta2 Adrenergic Receptor at Reperfusion Limits Myocardial Reperfusion Injury via an Interleukin-10-Dependent Anti-Inflammatory Pathway in the Spleen by Tian, Yikui, Miao, Bin, Charles, Eric J., Wu, Di, Kron, Irving L., French, Brent A., Yang, Zequan

“…Background: In addition to the airway-relaxing effects, β2 adrenergic receptor (β2AR) agonists are also found to have broad anti-inflammatory effects. The…”
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Plasmacytoid Dendritic Cells Mediate Myocardial Ischemia/Reperfusion Injury by Secreting Type I Interferons by Lai, Lina, Zhang, Aimee, Yang, Boris, Charles, Eric J., Kron, Irving L., Yang, Zequan

“…Background We previously demonstrated that ischemically injured cardiomyocytes release cell‐free DNA and HMGB1 (high mobility group box 1 protein) into…”
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The spleen contributes importantly to myocardial infarct exacerbation during post-ischemic reperfusion in mice via signaling between cardiac HMGB1 and splenic RAGE by Tian, Yikui, Pan, Dongfeng, Chordia, Mahendra D., French, Brent A., Kron, Irving L., Yang, Zequan

“…The spleen plays a critical role in post-infarct myocardial remodeling. However, the role of the spleen in exacerbating myocardial infarction (MI) during acute…”
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Myocardial infarct-sparing effect of adenosine A2A receptor activation is due to its action on CD4+ T lymphocytes by ZEQUAN YANG, DAY, Yuan-Ji, TOUFEKTSIAN, Marie-Claire, YAQIN XU, RAMOS, Susan I, MARSHALL, Melissa A, FRENCH, Brent A, LINDEN, Joel

“…We previously used adenosine A2A receptor (A2AR) knockout (KO) mice and bone marrow transplantation to show that the infarct-sparing effect of A2AR activation…”
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BDIDA-IoT: A Blockchain-Based Decentralized Identity Architecture Enhances the Efficiency of IoT Data Flow by Yang, Zequan, Liu, Yumeng, Jin, Xiaopeng, Luo, Xiaoling, Xu, Yuan, Li, Meng, Chen, Peng, Tang, Bixia, Lin, Baohui

“…With the booming development of the Internet of Things (IoT) industry, millions of data are generated every day. How to use and manage these data safely and…”
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Topical Neck Cooling Prolongs Survival of Rats with Intra-Abdominal Feculent Sepsis by Activation of the Vagus Nerve by Zhang, Aimee Y., Marsh, Katherine M., Rastogi, Radhika, Wu, Di, Charles, Eric J., Kron, Irving L., Sawyer, Robert G., Yang, Zequan

“…Global hypothermia prolongs survival in rats with intraabdominal feculent sepsis by inhibiting inflammatory responses. We hypothesized that topical neck…”
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Adenosine 2B Receptor Activation Reduces Myocardial Reperfusion Injury by Promoting Anti-Inflammatory Macrophages Differentiation via PI3K/Akt Pathway by French, Brent A., Kron, Irving L., Piras, Bryan A., Tian, Yikui, Yang, Zequan

“…Background. Activation of the adenosine A2B receptor (A2BR) can reduce myocardial ischemia/reperfusion (IR) injury. However, the mechanism underlying the…”
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Adenosine A2A receptor activation on CD4+ T lymphocytes and neutrophils attenuates lung ischemia–reperfusion injury by Sharma, Ashish K., MBBS, Laubach, Victor E., PhD, Ramos, Susan I, Zhao, Yunge, MD, PhD, Stukenborg, George, PhD, Linden, Joel, PhD, Kron, Irving L., MD, Yang, Zequan, MD, PhD

“…Objective Adenosine A2A receptor activation potently attenuates lung ischemia–reperfusion injury. This study tests the hypothesis that adenosine A2A receptor…”
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Therapeutic Efficacy of Alpha-Lipoic Acid against Acute Myocardial Infarction and Chronic Left Ventricular Remodeling in Mice by French, Brent A., Berr, Stuart S., Tian, Yikui, Yang, Zequan

“…Background. We hypothesized that daily administration of a potent antioxidant (α-lipoic acid: ALA) would protect the heart against both acute myocardial…”
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Acute hyperglycemia enhances oxidative stress and exacerbates myocardial infarction by activating nicotinamide adenine dinucleotide phosphate oxidase during reperfusion by Yang, Zequan, MD, Laubach, Victor E., PhD, French, Brent A., PhD, Kron, Irving L., MD

“…Objective Acute hyperglycemia is independently associated with larger myocardial infarct size in both diabetic and nondiabetic patients. We hypothesized that…”
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Atorvastatin at reperfusion reduces myocardial infarct size in mice by activating eNOS in bone marrow-derived cells by Tian, Yikui, Linden, Joel, French, Brent A, Yang, Zequan

“…The current study was designed to test our hypothesis that atorvastatin could reduce infarct size in intact mice by activating eNOS, specifically the eNOS in…”
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Topical Neck Cooling Without Systemic Hypothermia Attenuates Myocardial Ischemic Injury and Post-ischemic Reperfusion Injury by Zhang, Aimee, Rastogi, Radhika, Marsh, Katherine M., Yang, Boris, Wu, Di, Kron, Irving L., Yang, Zequan

“…Background Following acute myocardial infarction (MI), irreversible damage to the myocardium can only be reduced by shortening the duration between symptom…”
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CD4+ T lymphocytes mediate acute pulmonary ischemia–reperfusion injury by Yang, Zequan, MD, PhD, Sharma, Ashish K., MBBS, Linden, Joel, PhD, Kron, Irving L., MD, Laubach, Victor E., PhD

“…Objective Postischemic reperfusion of the lung triggers proinflammatory responses that stimulate injurious neutrophil chemotaxis. We hypothesized that T…”
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Outcomes of reoperative aortic valve replacement after previous sternotomy by LaPar, Damien J., MD, Yang, Zequan, MD, Stukenborg, George J., PhD, Peeler, Benjamin B., MD, Kern, John A., MD, Kron, Irving L., MD, Ailawadi, Gorav, MD

“…Objective Increasingly, patients with previous sternotomy require aortic valve replacement. We compared outcomes of reoperative aortic valve replacement after…”
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Infarct-sparing effect of A2A-adenosine receptor activation is due primarily to its action on lymphocytes by ZEQUAN YANG, DAY, Yuan-Ji, TOUFEKTSIAN, Marie-Claire, RAMOS, Susan I, MARSHALL, Melissa, WANG, Xin-Qun, FRENCH, Brent A, LINDEN, Joel

“…A2A-adenosine receptor (A2AAR) activation on reperfusion after ischemia reduces the size of myocardial infarction, but the mechanism of action has not been…”
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Crucial role of endogenous interleukin-10 production in myocardial ischemia/reperfusion injury by ZEQUAN YANG, ZINGARELLI, B, SZABO, C

“…The anti-inflammatory cytokine interleukin-10 (IL-10) has been detected in the plasma of patients with myocardial ischemia/reperfusion. The aim of our study…”
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Cumulative sum: a proficiency metric for basic endoscopic training by Hu, Yinin, MD, Jolissaint, Joshua S., BA, Ramirez, Adriana, MD, Gordon, Ryan, BS, Yang, Zequan, MD, Sawyer, Robert G., MD

“…Abstract Background As work hour restrictions increasingly limit some operative experiences, personalized evaluative methods are needed. We prospectively…”
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Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase by Liao, James K, Hafezi-Moghadam, Ali, Simoncini, Tommaso, Yang, Zequan, Limbourg, Florian P, Plumier, Jean-Christophe, Rebsamen, Michela C, Hsieh, Chung-Ming, Chui, Dao-Shan, Thomas, Kennard L, Prorock, Alyson J, Laubach, Victor E, Moskowitz, Michael A, French, Brent A, Ley, Klaus

“…Corticosteroids have been shown to exert beneficial effects in the treatment of acute myocardial infarction, but the precise mechanisms underlying their…”
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Effect of hypothermia on splenic leukocyte modulation and survival duration in severely septic rats by Willis, Rhett N., MD, Charles, Eric J., MD, Guidry, Christopher A., MD, MSc, Chordia, Mahendra D., PhD, Davies, Stephen W., MD, MPH, Yang, Zequan, MD, Sawyer, Robert G., MD

“…Abstract Background Therapeutic hypothermia (HT) in severe septic shock is associated with prolonged survival. We hypothesized that moderate HT would prolong…”
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